⊟IsrR[edit | edit source]
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⊟Genome View[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Regulation[edit | edit source]
⊟Transcription pattern[edit | edit source]
- data available for NCTC8325
- S.aureus Expression Data Browser
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ 1.0 1.1 1.2 Rodrigo H Coronel-Tellez, Mateusz Pospiech, Maxime Barrault, Wenfeng Liu, Valérie Bordeau, Christelle Vasnier, Brice Felden, Bruno Sargueil, Philippe Bouloc
sRNA-controlled iron sparing response in Staphylococci.
Nucleic Acids Res: 2022, 50(15);8529-8546
[PubMed:35904807] [WorldCat.org] [DOI] (I p) - ↑ Maxime Barrault, Elise Leclair, Etornam Kofi Kumeko, Eric Jacquet, Philippe Bouloc
Staphylococcal sRNA IsrR downregulates methylthiotransferase MiaB under iron-deficient conditions.
Microbiol Spectr: 2024;e0388823
[PubMed:39162503] [WorldCat.org] [DOI] (I a) - ↑ 3.0 3.1 Maxime Barrault, Svetlana Chabelskaya, Rodrigo H Coronel-Tellez, Claire Toffano-Nioche, Eric Jacquet, Philippe Bouloc
Staphylococcal aconitase expression during iron deficiency is controlled by an sRNA-driven feedforward loop and moonlighting activity.
Nucleic Acids Res: 2024;
[PubMed:38869061] [WorldCat.org] [DOI] (I a) - ↑ 4.0 4.1 4.2 4.3 4.4 Gustavo Rios-Delgado, Aubrey K G McReynolds, Emma A Pagella, Javiera Norambuena, Paul Briaud, Vincent Zheng, Matthew J Munneke, Jisun Kim, Hugo Racine, Ronan K Carroll, Ehud Zelzion, Eric Skaar, Jeffrey L Bose, Dane Parker, David Lalaouna, Jeffrey M Boyd
The Staphylococcus aureus non-coding RNA IsrR regulates TCA cycle activity and virulence.
Nucleic Acids Res: 2025, 53(4);
[PubMed:39704109] [WorldCat.org] [DOI] (I p) - ↑ Gustavo Rios-Delgado, Riley McFarlane, Vincent Zheng, Jisun Kim, Dane Parker, Thomas Kehl-Fie, David Lalaouna, Jeffrey M Boyd
The iron-regulated small regulatory RNA IsrR modulates expression of genes utilized for dioxygen metabolism and heme synthesis in Staphylococcus aureus.
mBio: 2025;e0141525
[PubMed:41042061] [WorldCat.org] [DOI] (I a) - ↑ 6.0 6.1 6.2 6.3 6.4 6.5 6.6 6.7 Gustavo Rios-Delgado, Riley McFarlane, Vincent Zheng, Jisun Kim, Dane Parker, Thomas Kehl-Fie, David Lalaouna, Jeffrey M Boyd
The iron-regulated small regulatory RNA IsrR modulates expression of genes utilized for dioxygen metabolism and heme synthesis in Staphylococcus aureus.
mBio: 2025;e0141525
[PubMed:41042061] [WorldCat.org] [DOI] (I a) - ↑ Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
PLoS Genet: 2016, 12(4);e1005962
[PubMed:27035918] [WorldCat.org] [DOI] (I e)
⊟Relevant publications[edit | edit source]
Alexander Ganske, Larissa Milena Busch, Christian Hentschker, Alexander Reder, Stephan Michalik, Kristin Surmann, Uwe Völker, Ulrike Mäder
Exploring the targetome of IsrR, an iron-regulated sRNA controlling the synthesis of iron-containing proteins in Staphylococcus aureus.
Front Microbiol: 2024, 15;1439352
[PubMed:39035440] [WorldCat.org] [DOI] (P e)
Larissa M Busch, Alexander Ganske, Sebastian Reißel, Lisa Bleul, Christian Hentschker, Hannes Wolfgramm, Leif Steil, Manuela Gesell Salazar, Marc Schaffer, Alexander Reder, Stephan Michalik, Christiane Wolz, Kristin Surmann, Uwe Völker, Ulrike Mäder
Linking Virulence and Iron Limitation Response in Staphylococcus aureus: The sRNA IsrR Is Involved in SaeRS Activation.
J Proteome Res: 2025, 24(7);3324-3342
[PubMed:40456523] [WorldCat.org] [DOI] (I p)