PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159JSNZLGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 03-AUG-2016

Views

• Read

More

• Edit
• History
• Edit source

⊟Summary

• organism: Staphylococcus aureus NCTC8325
locus tag: SAOUHSC_02050
pan locus tag^?: SAUPAN001674000
symbol: SAOUHSC_02050
pan gene symbol^?: —
• synonym:
• product: terminase small subunit

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SAOUHSC_02050
• symbol: SAOUHSC_02050
• product: terminase small subunit
• replicon: chromosome
• strand: -
• coordinates: 1950046..1950486
• length: 441
• essential: no DEG

⊟Accession numbers

• Gene ID: 3920500 NCBI
• RefSeq: YP_500543 NCBI
• BioCyc: G1I0R-1940 BioCyc
• MicrobesOnline: 1290499 MicrobesOnline

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  
  ATGAACGAAAAACAAAAGAGATTCGCAGATGAATATATAATGAATGGATGTAATGGTAAA
  AAAGCAGCAATTACAGCAGGTTATAGTAAGAAAACAGCAGAGTCTTTAGCAAGTCGATTG
  TTAAGAAATGTTAATGTTTCGGAATATATTAAAGAACGATTAGAACAGATACAAGAAGAG
  CGTTTAATGAGTATTACAGAAGCTTTAGCGTTATCTGCTTCTATTGCTAGAGGAGAACCT
  CAAGAGGCTTACAGTAAGAAATATGACCATTTAAACGATGAAGTGGAAAAAGAGGTTACT
  TACACAATCACACCAACTTTTGAAGAGCGTCAGAGATCTATTGACCACATACTAAAAGTA
  CATGGTGCGTATATCGATAAAAAAGAAATTACTCAGAAGAATATTGAGATTAATATTGGT
  GAGTACGATGACGAAAGTTAA
  60
  120
  180
  240
  300
  360
  420
  441
  

⊟Protein

⊟General

• locus tag: SAOUHSC_02050
• symbol: SAOUHSC_02050
• description: terminase small subunit
• length: 146
• theoretical pI: 5.13029
• theoretical MW: 16806.7
• GRAVY: -0.819863

⊟Function

• TIGRFAM:
• TheSEED  :
  • Phage terminase, small subunit
  Phages, Prophages, Transposable elements Phages, Prophages Phage head and packaging  Phage terminase, small subunit
• ⊞PFAM:
  no clan defined Terminase_2; Terminase small subunit (PF03592; HMM-score: 117.8)
  and 1 more
  DSRM (CL0196) dsrm; Double-stranded RNA binding motif (PF00035; HMM-score: 14.3)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• ⊞PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• ⊞DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.964
  • Cytoplasmic Membrane Score: 0.0004
  • Cell wall & surface Score: 0.0002
  • Extracellular Score: 0.0354
• ⊞LocateP: Intracellular
  • Prediction by SwissProt Classification: Cytoplasmic
  • Pathway Prediction: No pathway
  • Intracellular possibility: 1
  • Signal peptide possibility: -1
  • N-terminally Anchored Score: 1
  • Predicted Cleavage Site: No CleavageSite
• ⊞SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.013094
  • TAT(Tat/SPI): 0.000975
  • LIPO(Sec/SPII): 0.007163
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 88195734 NCBI
• RefSeq: YP_500543 NCBI
• UniProt: Q2FX50 UniProt
• STRING: 93061.SAOUHSC_02050 STRING

⊟Protein sequence

• MNEKQKRFADEYIMNGCNGKKAAITAGYSKKTAESLASRLLRNVNVSEYIKERLEQIQEERLMSITEALALSASIARGEPQEAYSKKYDHLNDEVEKEVTYTITPTFEERQRSIDHILKVHGAYIDKKEITQKNIEINIGEYDDES

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: SAOUHSC_02047 < SAOUHSC_02048 < SAOUHSC_02049 < SAOUHSC_02050
  predicted SigA promoter  : S810 < SAOUHSC_02019 < SAOUHSC_02020 < SAOUHSC_02021 < SAOUHSC_02022 < SAOUHSC_02023 < SAOUHSC_02025 < SAOUHSC_02026 < SAOUHSC_02027 < SAOUHSC_02028 < SAOUHSC_02029 < SAOUHSC_02030 < SAOUHSC_02031 < SAOUHSC_02033 < SAOUHSC_02034 < SAOUHSC_02035 < SAOUHSC_02036 < SAOUHSC_02037 < SAOUHSC_02038 < SAOUHSC_02040 < SAOUHSC_02041 < SAOUHSC_02042 < SAOUHSC_02043 < SAOUHSC_02044 < S811 < SAOUHSC_02046 < SAOUHSC_02047 < SAOUHSC_02048 < SAOUHSC_02049 < SAOUHSC_02050 < S812 < SAOUHSC_02051 < SAOUHSC_02052 < SAOUHSC_02053 < SAOUHSC_02054 < SAOUHSC_02055 < SAOUHSC_02056 < SAOUHSC_02057 < SAOUHSC_02058 < SAOUHSC_02059 < SAOUHSC_02060 < SAOUHSC_02061 < SAOUHSC_02062 < SAOUHSC_02063 < SAOUHSC_02064 < SAOUHSC_02065 < SAOUHSC_02066 < SAOUHSC_02067 < SAOUHSC_02068 < SAOUHSC_02069 < SAOUHSC_02070 < SAOUHSC_02071 < S813 < SAOUHSC_02072 < SAOUHSC_02073 < SAOUHSC_02074 < SAOUHSC_02075 < SAOUHSC_02076 < SAOUHSC_02077 < SAOUHSC_02078 < SAOUHSC_02079 < SAOUHSC_02080 < S816 < SAOUHSC_02081 < SAOUHSC_02083

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser:   
  
  ⊟Multi-gene expression profiles

  Compare with:

  Conditions

  Select all flucRPMI-exp RPMI-exp-A2 vancRPMI-exp RPMI-exp-A1 TSB-exp-A TSB-exp-C ciproTSB-exp T/SmxTSB-exp clindTSB-exp lineTSB-exp eryTSB-exp TSB-exp-B3 flucTSB-exp TSB-exp-B2 vancTSB-exp TSB-exp-B1 RPMI/FCS-exp colist-exp intTHP1-2h intTHP1-6h intS9-6h intS9-2h TSB-t2-C TSB-t4-C flucTSB-t4 TSB-t2-B1 TSB-t4-B1 CDM-t2 CDM-t4 T/SmxTSB-t4 TSB-t4-B3 lineTSB-t4 TSB-t4-B2 vancTSB-t4 eryTSB-t4 clindTSB-t4 ciproTSB-t4 pMEM-t2-C1 pMEM-t4-C1 CO2-6h CO2-2h anaer-2h nonad50-1h CO2-1h nonad25-1h pMEM-exp-C2 pMEM-exp-C1 CDM-exp plasma-t4 vancRPMI-t4 flucRPMI-t4 RPMI-t4-A2 RPMI-t2-A1 plasma-exp

  
  
  Click on any data point to display a description of the corresponding condition!

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊞Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊞Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications