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⊟Summary[edit | edit source]
- pan ID?: SAUPAN005398000
- symbol?: atpF
- synonym:
- description?: F0F1 ATP synthase subunit B
- F0F1 ATP synthase subunit B
- ATP synthase subunit B
- ATP synthase F0F1 subunit B
- ATP synthase FO, subunit B
- ATP synthase B chain
- ATP synthase F0, B subunit
- ATP synthase F0 subunit B
- ATP synthase subunit beta, AtpB_1
- putative ATP synthase subunit b
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 5560444..5560965
- synteny block?: BlockID0041940
- occurrence?: in 100% of 34 strains
atpF : F0F1 ATP synthase subunit B [1]
ATP synthases couple proton translocation across membranes to rotational energy, conformational change and, ultimately, ATP generation. The F0 portion is a multimeric membrane-embedded proton channel (ab2c10) while the F1 portion is a multimeric cytoplasmic structure (α3β3γδε) that binds ADP and phosphate. When necessary, this process can also be run in reverse to generate a proton gradient at the expense of ATP. AtpF encodes F0 subunit B, the brace that connects the non-rotatory proton channel stator and the cytoplasmic F1 complex via the δ subunit. This brace prevents free rotation of the F1 subunit when coupled to the F0 C-ring flywheel.
⊟Orthologs[edit | edit source]
04-02981:
SA2981_2047 (atpF)
08BA02176:
C248_2121 (atpF)
11819-97:
MS7_2123 (atpF)
6850:
RSAU_001945 (atpF)
71193:
ST398NM01_2149
ECT-R 2:
ECTR2_1963 (atpF)
ED133:
SAOV_2148c
ED98:
SAAV_2162 (atpF)
HO 5096 0412:
SAEMRSA15_20150 (atpF)
JH1:
SaurJH1_2181
JH9:
SaurJH9_2143
JKD6008:
SAA6008_02145 (atpB_1)
JKD6159:
SAA6159_02021 (atpB_1)
JSNZ:
JSNZ_002068
LGA251:
SARLGA251_19080 (atpF)
M013:
M013TW_2066
MRSA252:
SAR2195 (atpF)
MSHR1132:
SAMSHR1132_19300
MSSA476:
SAS2010
Mu3:
SAHV_2091 (atpF)
Mu50:
SAV2107 (atpF)
MW2:
MW2031 (atpF)
RF122:
SAB1991c (atpF)
ST398:
SAPIG2149 (atpF)
T0131:
SAT0131_02269 (oppC)
TCH60:
HMPREF0772_11084 (atpF)
TW20:
SATW20_22450 (atpF)
USA300_TCH1516:
USA300HOU_2097 (atpF)
VC40:
SAVC_09410
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MTETANLFVLGAAGGVEWGTVIVQVLTFIVLLALLKKFAWGPLKDVMDKRERDINRDIDD
N315 MTETANLFVLGAAGGVEWGTVIVQVLTFIVLLALLKKFAWGPLKDVMDKRERDINRDIDD
NCTC8325 MTETANLFVLGAAGGVEWGTVIVQVLTFIVLLALLKKFAWGPLKDVMDKRERDINRDIDD
Newman MTETANLFVLGAAGGVEWGTVIVQVLTFIVLLALLKKFAWGPLKDVMDKRERDINRDIDD
USA300_FPR3757 MTETANLFVLGAAGGVEWGTVIVQVLTFIVLLALLKKFAWGPLKDVMDKRERDINRDIDD
************************************************************
COL AEQAKLNAQKLEEENKQKLKETQEEVQKILEDAKVQARQQQEQIIHEANVRANGMIETAQ
N315 AEQAKLNAQKLEEENKQKLKETQEEVQKILEDAKVQARQQQEQIIHEANVRANGMIETAQ
NCTC8325 AEQAKLNAQKLEEENKQKLKETQEEVQKILEDAKVQARQQQEQIIHEANVRANGMIETAQ
Newman AEQAKLNAQKLEEENKQKLKETQEEVQKILEDAKVQARQQQEQIIHEANVRANGMIETAQ
USA300_FPR3757 AEQAKLNAQKLEEENKQKLKETQEEVQKILEDAKVQARQQQEQIIHEANVRANGMIETAQ
************************************************************
COL SEINSQKERAIADINNQVSELSVLIASKVLRKEISEQDQKALVDKYLKEAGDK
N315 SEINSQKERAIADINNQVSELSVLIASKVLRKEISEQDQKALVDKYLKEAGDK
NCTC8325 SEINSQKERAIADINNQVSELSVLIASKVLRKEISEQDQKALVDKYLKEAGDK
Newman SEINSQKERAIADINNQVSELSVLIASKVLRKEISEQDQKALVDKYLKEAGDK
USA300_FPR3757 SEINSQKERAIADINNQVSELSVLIASKVLRKEISEQDQKALVDKYLKEAGDK
*****************************************************
- ↑ G Deckers-Hebestreit, K Altendorf
The F0F1-type ATP synthases of bacteria: structure and function of the F0 complex.
Annu Rev Microbiol: 1996, 50;791-824
[PubMed:8905099] [WorldCat.org] [DOI] (P p)Martin Vestergaard, Sahar Roshanak, Hanne Ingmer
Targeting the ATP Synthase in Staphylococcus aureus Small Colony Variants, Streptococcus pyogenes and Pathogenic Fungi.
Antibiotics (Basel): 2021, 10(4);
[PubMed:33918382] [WorldCat.org] [DOI] (P e)