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⊟Summary[edit | edit source]
- pan ID?: SAUPAN005397000
- symbol?: atpH
- synonym:
- description?: F0F1 ATP synthase subunit delta
- F0F1 ATP synthase subunit delta
- ATP synthase subunit delta
- ATP synthase F0F1 subunit delta
- FOF1-ATP synthase, subunit delta
- ATP synthase delta chain
- ATP synthase F1, delta subunit
- ATP synthase F1 sector delta subunit
- ATP synthase F1 subunit delta
- putative ATP synthase delta chain
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 5559905..5560444
- synteny block?: BlockID0041930
- occurrence?: in 100% of 34 strains
atpH : F0F1 ATP synthase subunit delta [1]
ATP synthases couple proton translocation across membranes to rotational energy, conformational change and, ultimately, ATP generation. The F0 portion is a multimeric membrane-embedded proton channel (ab2c10) while the F1 portion is a multimeric cytoplasmic structure (α3β3γδε) that binds ADP and phosphate. When necessary, this process can also be run in reverse to generate a proton gradient at the expense of ATP. AtpH encodes F1 subunit δ, the "solder" protein linking F0 and F1 complexes through binding the F0 subunit B "brace" protein and the F1 α3β3 hexamer. This maintains a functional association counteracting the free-rotation torque applied by the central stalk rotor.
⊟Orthologs[edit | edit source]
04-02981:
SA2981_2046 (atpH)
08BA02176:
C248_2120 (atpH)
11819-97:
MS7_2122 (atpH)
6850:
RSAU_001944 (atpH)
71193:
ST398NM01_2148
ECT-R 2:
ECTR2_1962 (atpH)
ED133:
SAOV_2147c
ED98:
SAAV_2161 (atpH)
HO 5096 0412:
SAEMRSA15_20140 (atpH)
JH1:
SaurJH1_2180
JH9:
SaurJH9_2142
JKD6008:
SAA6008_02144 (atpD)
JKD6159:
SAA6159_02020 (atpD)
JSNZ:
JSNZ_002067
LGA251:
SARLGA251_19070 (atpH)
M013:
M013TW_2065
MRSA252:
SAR2194 (atpH)
MSHR1132:
SAMSHR1132_19290
MSSA476:
SAS2009
Mu3:
SAHV_2090 (atpH)
Mu50:
SAV2106 (atpH)
MW2:
MW2030 (atpH)
RF122:
SAB1990c (atpH)
ST398:
SAPIG2148 (atpH)
T0131:
SAT0131_02268 (oppB)
TCH60:
HMPREF0772_11085 (atpH)
TW20:
SATW20_22440 (atpH)
USA300_TCH1516:
USA300HOU_2096 (atpH)
VC40:
SAVC_09405
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MVKVANKYAKALFDVSLDTNNLETINEELTVINEAVKDKIEQLRMVDSNPTQTAEQRREL
N315 MVKVANKYAKALFDVSLDTNNLETINEELTVINEAVKDKIEQLKMVDSNPTQTAEQRREL
NCTC8325 MVKVANKYAKALFDVSLDTNNLETINEELTVINEAVKDKIEQLRMVDSNPTQTAEQRREL
Newman MVKVANKYAKALFDVSLDTNNLETINEELTVINEAVKDKIEQLRMVDSNPTQTAEQRREL
USA300_FPR3757 MVKVANKYAKALFDVSLDTNNLETINEELTVINEAVKDKIEQLRMVDSNPTQTAEQRREL
*******************************************:****************
COL INGVFTDINPYIKNMMYVLADNRHISLIADVFKAFQSLYNGHYNQDFATIESTYELSQEE
N315 INGVFTDINPYIKNMMYVLADNRHISLIADVFKAFQSLYNGHYNQDFATIESTYELSQEE
NCTC8325 INGVFTDINPYIKNMMYVLADNRHISLIADVFKAFQSLYNGHYNQDFATIESTYELSQEE
Newman INGVFTDINPYIKNMMYVLADNRHISLIADVFKAFQSLYNGHYNQDFATIESTYELSQEE
USA300_FPR3757 INGVFTDINPYIKNMMYVLADNRHISLIADVFKAFQSLYNGHYNQDFATIESTYELSQEE
************************************************************
COL LDKIVKLVTQQTKLSKVIVDTKINPDLIGGFRVKVGTTVLDGSVRNDLVQLQRKFRRVN
N315 LDKIVKLVTQQTKLSKVIVDTKINPDLIGGFRVKVGTTVLDGSVRNDLVQLQRKFRRVN
NCTC8325 LDKIVKLVTQQTKLSKVIVDTKINPDLIGGFRVKVGTTVLDGSVRNDLVQLQRKFRRVN
Newman LDKIVKLVTQQTKLSKVIVDTKINPDLIGGFRVKVGTTVLDGSVRNDLVQLQRKFRRVN
USA300_FPR3757 LDKIVKLVTQQTKLSKVIVDTKINPDLIGGFRVKVGTTVLDGSVRNDLVQLQRKFRRVN
***********************************************************
- ↑ G Deckers-Hebestreit, K Altendorf
The F0F1-type ATP synthases of bacteria: structure and function of the F0 complex.
Annu Rev Microbiol: 1996, 50;791-824
[PubMed:8905099] [WorldCat.org] [DOI] (P p)Martin Vestergaard, Sahar Roshanak, Hanne Ingmer
Targeting the ATP Synthase in Staphylococcus aureus Small Colony Variants, Streptococcus pyogenes and Pathogenic Fungi.
Antibiotics (Basel): 2021, 10(4);
[PubMed:33918382] [WorldCat.org] [DOI] (P e)