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FunGene: 08-OCT-2024

Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000954
  • pan locus tag?: SAUPAN003152000
  • symbol: opp4B
  • pan gene symbol?: opp4B
  • synonym:
  • product: oligopeptide ABC transporter permease

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000954
  • symbol: opp4B
  • product: oligopeptide ABC transporter permease
  • replicon: chromosome
  • strand: +
  • coordinates: 959378..960340
  • length: 963
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGGTTAAATTAATATTAAAGAGATTAGGTTTAATGATTCCGTTACTAATTTTAATTTCT
    ATTGTTGTATTTTCATTAGGTATCATTCAACCAGGAGATCCATTTTCAGATTTACAAAAC
    GGTAAAATAAAACAAGAAGCAATAAATGCACAAAGGGAAAAGTTAGGCCTCAACGACTCT
    ATACCACATCAATACATTAGATGGGTCAATCATGTTATACACGGTGATTTAGGAGAGTCA
    ATCAAATATAAAAGGCCGGTAATTGATGTTATTGAGGAAAGAATTCCAAATACAATATTA
    CTCGGTGCTATGTCATTAATTATTACTTATATTATCTCATTTGCTTTAGGAATAACGTCA
    GGTCGATATTCTTACAGTTTGACTGATTATACTGTGCAAATATTTAATTATTTGATGTTA
    GCTATTCCATCTTTTATTGCGGGAGTATTTGCAATTTTTATTTTTTCTTTTGAATTACAA
    TGGTTTCCGTTTCAAGGTTCTGTTGATATTAACCTTAAAGAAGGTACTTTTGAATATTAT
    ATGAGTAAAATTTATCATACATTTTTGCCTGCATTAACTTTAGGATTATTATCTACTGCT
    GGTTATATTCAATATTTACGTAATGATATTATTGAAAATTCTAAAAAAGATTATGTATTG
    ACGGCAAGGTCAAAAGGATTATCTATGAATAAAATTTATAATAAACATATACTGAGAAAT
    TCTTTAATACCTATTATTACATTTTTAGGTGCTGATATTGTAAGTATTTTAGGTGGAGCT
    GTGATTACTGAGACTATCTTTTCATATAACGGTATCGGTAAATTATTTTTAGAATCGGTA
    ATAGGTCAAGACTATCCATTAATGATGGCATTAACGTTATTTTTCTCATTTTTAGGTTTA
    CTGGGTAATTTGATTTCTGATATTACTTATGGATTTATAGATCCAAGAATTAGAAGTAAC
    TAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    963

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: JSNZ_000954
  • symbol: Opp4B
  • description: oligopeptide ABC transporter permease
  • length: 320
  • theoretical pI: 8.94727
  • theoretical MW: 36061.2
  • GRAVY: 0.454375

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Cations and iron carrying compounds nickel ABC transporter, permease subunit NikB (TIGR02789; EC 3.6.3.24; HMM-score: 236.8)
    and 3 more
    Metabolism Transport and binding proteins Cations and iron carrying compounds nickel ABC transporter, permease subunit NikC (TIGR02790; EC 3.6.3.24; HMM-score: 23.3)
    Metabolism Transport and binding proteins Anions phosphate ABC transporter, permease protein PstA (TIGR00974; HMM-score: 19.9)
    Metabolism Transport and binding proteins Anions phosphate ABC transporter, permease protein PstC (TIGR02138; HMM-score: 19)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    BPD_transp_1 (CL0404) BPD_transp_1; Binding-protein-dependent transport system inner membrane component (PF00528; HMM-score: 141)
    and 2 more
    no clan defined BPD_transp_1_N; Binding-prot-dependent transport system membrane comp, N-term (PF19300; HMM-score: 44.4)
    Inovirus_G7P_2; Tail virion protein G7P (PF19978; HMM-score: 8)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 1
    • Cell wall & surface Score: 0
    • Extracellular Score: 0
  • LocateP:
  • SignalP: Signal peptide SP(Sec/SPI) length 34 aa
    • SP(Sec/SPI): 0.494092
    • TAT(Tat/SPI): 0.001447
    • LIPO(Sec/SPII): 0.049725
    • Cleavage Site: CS pos: 34-35. GDP-FS. Pr: 0.0650
  • predicted transmembrane helices (TMHMM): 6

Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

Protein sequence[edit | edit source]

  • MVKLILKRLGLMIPLLILISIVVFSLGIIQPGDPFSDLQNGKIKQEAINAQREKLGLNDSIPHQYIRWVNHVIHGDLGESIKYKRPVIDVIEERIPNTILLGAMSLIITYIISFALGITSGRYSYSLTDYTVQIFNYLMLAIPSFIAGVFAIFIFSFELQWFPFQGSVDINLKEGTFEYYMSKIYHTFLPALTLGLLSTAGYIQYLRNDIIENSKKDYVLTARSKGLSMNKIYNKHILRNSLIPIITFLGADIVSILGGAVITETIFSYNGIGKLFLESVIGQDYPLMMALTLFFSFLGLLGNLISDITYGFIDPRIRSN

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator: CodY (repression) regulon
    CodY(TF)important in Amino acid metabolism;  regulation predicted or transferred from N315 and NCTC 8325  [2]

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

  1. Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)
  2. Hannes Wolfgramm, Larissa Milena Busch, Jöran Tebben, Henry Mehlan, Lisa Hagenau, Thomas Sura, Tilly Hoffmüller, Elisa Bludau, Manuela Gesell Salazar, Alexander Reder, Stephan Michalik, Leif Steil, Kristin Surmann, Ulrike Mäder, Silva Holtfreter, Uwe Völker
    Integrated genomic and proteomic analysis of the mouse-adapted Staphylococcus aureus strain JSNZ.
    Curr Res Microb Sci: 2025, 9;100489
    [PubMed:41146725] [WorldCat.org] [DOI] (I e)

Relevant publications[edit | edit source]