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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_1514 [new locus tag: SAUSA300_RS08265 ]
  • pan locus tag?: SAUPAN004135000
  • symbol: fur
  • pan gene symbol?: zur
  • synonym:
  • product: ferric uptake regulation protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_1514 [new locus tag: SAUSA300_RS08265 ]
  • symbol: fur
  • product: ferric uptake regulation protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1664812..1665222
  • length: 411
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGAATACAAATGATGCTATTAAAATTTTAAAAGAGAACGGTTTAAAATATACAGATAAA
    CGTAAAGATATGTTAGATATTTTTGTCGAAGAAGATAAGTATATAAACGCAAAGTATATA
    CAACAAGTTATGGATGAAAATTATCCTGGAATTTCATTCGACACAATATATAGAAACCTG
    CACTTATTTAAAGATTTAGGAATTATTGAAAATACAGAACTTGATGGTGAAATGAAGTTT
    AGAATCGCTTGTACAAACCATCATCATCATCATTTTATCTGTGAAAAGTGTGGAGATACA
    AAGGTAATAGATTATTGTCCAATAGATCAGATAAAATTATCACTACCTGGTGTTAATATT
    CACAAACACAAACTTGAAGTTTATGGTGTATGTGAGTCTTGCCAAGATTAA
    60
    120
    180
    240
    300
    360
    411

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SAUSA300_1514 [new locus tag: SAUSA300_RS08265 ]
  • symbol: Fur
  • description: ferric uptake regulation protein
  • length: 136
  • theoretical pI: 6.07084
  • theoretical MW: 15922.1
  • GRAVY: -0.516912

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • Zinc uptake regulation protein Zur
    Stress Response Oxidative stress Oxidative stress  Zinc uptake regulation protein ZUR
  • PFAM:
    HTH (CL0123) FUR; Ferric uptake regulator family (PF01475; HMM-score: 111.5)
    and 1 more
    no clan defined F-protein; Negative factor, (F-Protein) or Nef (PF00469; HMM-score: 12.6)

⊟Structure, modifications & cofactors[edit | edit source]

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002478
    • TAT(Tat/SPI): 0.000134
    • LIPO(Sec/SPII): 0.000435
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MNTNDAIKILKENGLKYTDKRKDMLDIFVEEDKYINAKYIQQVMDENYPGISFDTIYRNLHLFKDLGIIENTELDGEMKFRIACTNHHHHHFICEKCGDTKVIDYCPIDQIKLSLPGVNIHKHKLEVYGVCESCQD

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: Zur* (repression) regulon
    Zur*(TF)important in Zinc homeostasis; RegPrecise    transcription unit transferred from N315 data RegPrecise 

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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