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NCBI: 26-AUG-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus N315
- locus tag: SA1678 [new locus tag: SA_RS09630 ]
- pan locus tag?: SAUPAN004840000
- symbol: SA1678
- pan gene symbol?: perR
- synonym:
- product: hypothetical protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SA1678 [new locus tag: SA_RS09630 ]
- symbol: SA1678
- product: hypothetical protein
- replicon: chromosome
- strand: -
- coordinates: 1924624..1925070
- length: 447
- essential: no DEG other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 1124561 NCBI
- RefSeq: NP_374968 NCBI
- BioCyc: see SA_RS09630
- MicrobesOnline: 103994 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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421ATGAGTGTTGAAATAGAATCAATTGAACATGAACTAGAAGAATCAATTGCATCATTGCGA
CAAGCAGGCATAAGAATTACACCTCAAAGACAAGCAATATTACGTTATTTAATTTCTTCA
CATACTCATCCAACAGCTGATGAAATTTATCAAGCACTTTCACCTGATTTTCCAAATATA
AGTGTTGCGACAATATATAATAACTTAAGAGTGTTTAAAGATATTGGAATTGTAAAAGAA
TTAACATATGGAGACTCATCAAGTCGATTCGACTTTAATACACATAATCATTATCATATT
ATATGTGAACAATGTGGTAAGATTGTTGATTTTCAATATCCACAGTTAAATGAAATTGAA
AGATTAGCTCAGCATATGACTGACTTTGACGTAACACATCATCGAATGGAAATTTATGGA
GTTTGTAAAGAATGCCAAGATAAATAA60
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447
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SA1678 [new locus tag: SA_RS09630 ]
- symbol: SA1678
- description: hypothetical protein
- length: 148
- theoretical pI: 5.47242
- theoretical MW: 17197.2
- GRAVY: -0.419595
⊟Function[edit | edit source]
- TIGRFAM:
- TheSEED :
- Peroxide stress regulator PerR, FUR family
- PFAM: HTH (CL0123) FUR; Ferric uptake regulator family (PF01475; HMM-score: 137.8)and 11 moreHTH_20; Helix-turn-helix domain (PF12840; HMM-score: 17.2)no clan defined Type2_restr_D3; Type-2 restriction enzyme D3 domain (PF16902; HMM-score: 16.5)SR1P; SR1 protein (PF13790; HMM-score: 14.9)C2H2-zf (CL0361) zf-BED; BED zinc finger (PF02892; HMM-score: 13.8)no clan defined E6; Early Protein (E6) (PF00518; HMM-score: 13.6)HTH (CL0123) HTH_11; HTH domain (PF08279; HMM-score: 13.5)no clan defined DASH_Hsk3; DASH complex subunit Hsk3 like (PF08227; HMM-score: 12.4)Zn_Beta_Ribbon (CL0167) zf-dskA_traR; Prokaryotic dksA/traR C4-type zinc finger (PF01258; HMM-score: 11.1)no clan defined DUF2039; Uncharacterized conserved protein (DUF2039) (PF10217; HMM-score: 10.8)Zn_Beta_Ribbon (CL0167) TF_Zn_Ribbon; TFIIB zinc-binding (PF08271; HMM-score: 10.5)Ribosomal_L37e; Ribosomal protein L37e (PF01907; HMM-score: 10.4)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors: Hydrogen peroxide; Iron ion (Fe2+) and Manganese ion (Mn2+) act as corepressor
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- LocateP: Intracellular
- Prediction by SwissProt Classification: Cytoplasmic
- Pathway Prediction: No pathway
- Intracellular possibility: 1
- Signal peptide possibility: -1
- N-terminally Anchored Score: -1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.008604
- TAT(Tat/SPI): 0.003454
- LIPO(Sec/SPII): 0.001341
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MSVEIESIEHELEESIASLRQAGIRITPQRQAILRYLISSHTHPTADEIYQALSPDFPNISVATIYNNLRVFKDIGIVKELTYGDSSSRFDFNTHNHYHIICEQCGKIVDFQYPQLNEIERLAQHMTDFDVTHHRMEIYGVCKECQDK
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: SA1678 < SA1679 < SA1680
⊟Regulation[edit | edit source]
- regulators: FapR* (repression) regulon, PerR* (repression) regulon
FapR* (TF) important in Fatty acid biosynthesis; RegPrecise PerR* (TF) important in Oxidative stress response; RegPrecise
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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