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NCBI: 26-AUG-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA1941 [new locus tag: SA_RS11150 ]
  • pan locus tag?: SAUPAN005436000
  • symbol: dps
  • pan gene symbol?: dps
  • synonym:
  • product: general stress protein 20U

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA1941 [new locus tag: SA_RS11150 ]
  • symbol: dps
  • product: general stress protein 20U
  • replicon: chromosome
  • strand: -
  • coordinates: 2190733..2191176
  • length: 444
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGAGTAATCAACAAGATGTTGTAAAAGAATTGAATCAACAAGTAGCAAACTGGACAGTA
    GCTTACACAAAGCTACATAATTTCCACTGGTATGTGAAAGGACCTAACTTCTTCTCATTA
    CACGTTAAATTTGAAGAATTATATAATGAAGCAAGCCAATATGTAGACGAATTAGCTGAA
    AGAATTTTAGCGGTAGGAGGAAACCCTGTAGGTACATTAACTGAATGCTTAGAGCAATCA
    ATTGTTAAAGAAGCTGCGAAAGGTTACTCTGCAGAACAAATGGTTGAAGAATTATCACAA
    GACTTCACAAATATCTCAAAACAATTAGAAAACGCAATCGAAATTGCTGGTAATGCTGGC
    GATGATGTATCAGAAGATATGTTTATAGGTATGCAAACATCAGTAGATAAACATAATTGG
    ATGTTTAAATCTTACTTAAGCTAA
    60
    120
    180
    240
    300
    360
    420
    444

⊟Protein[edit | edit source]

Protein Data Bank: 2D5K

⊟General[edit | edit source]

  • locus tag: SA1941 [new locus tag: SA_RS11150 ]
  • symbol: Dps
  • description: general stress protein 20U
  • length: 147
  • theoretical pI: 4.29468
  • theoretical MW: 16691.5
  • GRAVY: -0.394558

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Cations and iron carrying compounds bacterioferritin (TIGR00754; HMM-score: 17.9)
  • TheSEED  :
    • DNA protection during starvation protein
    Stress Response Oxidative stress Oxidative stress  Ferroxidase (EC 1.16.3.1)
    and 2 more
    Stress Response Oxidative stress Oxidative stress  Iron-binding ferritin-like antioxidant protein
    Stress Response Oxidative stress Oxidative stress  Non-specific DNA-binding protein Dps
  • PFAM:
    Ferritin (CL0044) Ferritin; Ferritin-like domain (PF00210; HMM-score: 110.4)
    and 5 more
    no clan defined Lipase_bact_N; Bacterial virulence factor lipase N-terminal (PF12262; HMM-score: 17.1)
    Ferritin (CL0044) DUF2383; Domain of unknown function (DUF2383) (PF09537; HMM-score: 15.1)
    no clan defined DUF4455; Domain of unknown function (DUF4455) (PF14643; HMM-score: 13.5)
    BST2; Bone marrow stromal antigen 2 (PF16716; HMM-score: 13)
    SlyX; SlyX (PF04102; HMM-score: 11.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.67
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 0.15
    • Extracellular Score: 0.17
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004322
    • TAT(Tat/SPI): 0.000179
    • LIPO(Sec/SPII): 0.000538
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: PerR* (repression) regulon
    PerR*(TF)important in Oxidative stress response; RegPrecise 

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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