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NCBI: 26-AUG-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus N315
- locus tag: SA1679 [new locus tag: SA_RS09635 ]
- pan locus tag?: SAUPAN004842000
- symbol: SA1679
- pan gene symbol?: —
- synonym:
- product: hypothetical protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SA1679 [new locus tag: SA_RS09635 ]
- symbol: SA1679
- product: hypothetical protein
- replicon: chromosome
- strand: -
- coordinates: 1925167..1926117
- length: 951
- essential: no DEG other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 1124562 NCBI
- RefSeq: NP_374969 NCBI
- BioCyc: see SA_RS09635
- MicrobesOnline: 103995 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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901ATGAAAGTTGTTGGGTTAAATCGTATGCGTGAAGTTGAAACTGAATTACAACAACGCTTT
TCAGATTTAGATTTTAAATTTTATAAAAAAGCATCAGAAATACCTGAGAGTGACTTGGCT
GATTTAGATATATTAGTTGGTTATGATGGCGGTATCAATGAGGCATTTTTACAACGTTGC
CCGAATTTAAAATGGATTGCATGGTTTGCAACGGGTGTAAATACATTACCGTTAGATTAT
ATTGCAGATCACGGCATACTTTTAACTAATGGAAAAGGTGTTCAAGCTAAACAATTATCT
GAATACATTTTAGCTTTCATTTTAGATGATTATAAAAAGATGAAACTATCATATGATAAC
CAAAGACAACATATATATGATTCGAAAATAACTGGTAAACGCCTATCAGGACAAACAGTT
TTATTTTTAGGTACAGGTGCAATTGCTACTAGAACTGCGAAGTTAGCAAAGGCTTTTAAT
ATGAATTTAATTGGTCTGAGCAAGTCAGGTCAGAACAAAGATGAGTTTGACGAGATATAT
ACTATCGAATCACTTGAAAGCACATTACCAAATGCTGACATTATTATAAATGCTTTACCA
GAAACGCAAGAAACGATTCATTTACTAAAGAAAAAACATTTTGAATTAATGAAAGATGAA
GCACTTTTTATAAATATAGGACGAGGTAGCATAGTTAAAGAAGCGCTCTTAATAGAAGTA
TTAAAAAGTAAAGTTATTCGACATGCATATTTAGATGTGTTTGAAAATGAACCTTTGAAA
CCTAATCATGAATTATATGAATTGGAAAATGTAACTATAACAGCGCATATAACTGGTAAT
GATTATGAGGCAAAGTATGACTTATTAGATATTTTTAAAAACAATCTAGTTAATTTTCTC
AATAAGAATGGTCTAATTGAGAATGAAGTTGATGCTAAAAAAGGCTATTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SA1679 [new locus tag: SA_RS09635 ]
- symbol: SA1679
- description: hypothetical protein
- length: 316
- theoretical pI: 5.46726
- theoretical MW: 35938.9
- GRAVY: -0.262658
⊟Function[edit | edit source]
- TIGRFAM: Amino acid biosynthesis Serine family phosphoglycerate dehydrogenase (TIGR01327; EC 1.1.1.95; HMM-score: 128.8)and 1 moreEnergy metabolism Amino acids and amines adenosylhomocysteinase (TIGR00936; EC 3.3.1.1; HMM-score: 16.4)
- TheSEED :
- Phosphoglycerate dehydrogenase-like protein
- PFAM: NADP_Rossmann (CL0063) 2-Hacid_dh_C; D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain (PF02826; HMM-score: 168.4)and 5 moreForm_Glyc_dh (CL0325) 2-Hacid_dh; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (PF00389; HMM-score: 46.4)DpaA_N; Dipicolinate synthase subunit A N-terminal domain (PF16924; HMM-score: 16)NADP_Rossmann (CL0063) Shikimate_DH; Shikimate / quinate 5-dehydrogenase (PF01488; HMM-score: 15.7)AdoHcyase_NAD; S-adenosyl-L-homocysteine hydrolase, NAD binding domain (PF00670; HMM-score: 14.7)AlaDh_PNT_C; Alanine dehydrogenase/PNT, C-terminal domain (PF01262; HMM-score: 11.8)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- LocateP: Intracellular
- Prediction by SwissProt Classification: Cytoplasmic
- Pathway Prediction: No pathway
- Intracellular possibility: 1
- Signal peptide possibility: -1
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.008652
- TAT(Tat/SPI): 0.000253
- LIPO(Sec/SPII): 0.000782
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MKVVGLNRMREVETELQQRFSDLDFKFYKKASEIPESDLADLDILVGYDGGINEAFLQRCPNLKWIAWFATGVNTLPLDYIADHGILLTNGKGVQAKQLSEYILAFILDDYKKMKLSYDNQRQHIYDSKITGKRLSGQTVLFLGTGAIATRTAKLAKAFNMNLIGLSKSGQNKDEFDEIYTIESLESTLPNADIIINALPETQETIHLLKKKHFELMKDEALFINIGRGSIVKEALLIEVLKSKVIRHAYLDVFENEPLKPNHELYELENVTITAHITGNDYEAKYDLLDIFKNNLVNFLNKNGLIENEVDAKKGY
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: SA1678 < SA1679 < SA1680
⊟Regulation[edit | edit source]
- regulator: PerR* (repression) regulon
PerR* (TF) important in Oxidative stress response; RegPrecise
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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