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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_001451
  • pan locus tag?: SAUPAN003926000
  • symbol: aroC
  • pan gene symbol?: aroC
  • synonym:
  • product: chorismate synthase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_001451
  • symbol: aroC
  • product: chorismate synthase
  • replicon: chromosome
  • strand: -
  • coordinates: 1498457..1499623
  • length: 1167
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGAGATATCTAACTTCAGGAGAATCACATGGACCTCAATTAACAGTTATTGTCGAAGGT
    ATACCAGCAAATTTAGAAATTAAGGTTGAGGATATTAATAAAGAAATGTTCAAGCGTCAA
    GGGGGTTATGGTCGTGGCCGACGTATGCAAATTGAGAAAGATACAGTAGAAATAGTATCA
    GGCGTTAGAAATGGTTATACATTAGGTAGTCCAATTACTATGGTTGTAACCAATGATGAC
    TTTACGCATTGGAGAAAAATTATGGGAGCAGCTCCAATAAGTGAAGAAGAACGTGAAAAT
    ATGAAACGTACTATTACAAAACCAAGACCTGGTCATGCAGATTTGGTTGGAGGTATGAAA
    TATAATCATCGTGATTTACGAAATGTGCTAGAGCGATCATCTGCTAGAGAAACAGCAGCT
    CGAGTTGCAGTCGGTGCCTTATGTAAAGTGTTATTACAACAGTTAGATATCGATATATAC
    AGTCGTGTTGTTGAAATAGGTGGAATTAAAGATAAAGATTTTTATGATTCAGAAACATTT
    AAAGCAAATCTTGATCGTAATGATGTTCGTGTAATTGATGACAGTATCGCACAAGCAATG
    CGAGATAAAATTGACGAAGCTAAAAATGAAGGAGATTCAATTGGCGGTGTCGTTCAAGTT
    GTAGTTGAAAATATGCCTGTTGGTGTTGGTAGTTATGTGCATTATGATCGTAAGTTAGAT
    GGCAAGATTGCACAAGGTGTTGTCAGCATAAATGCTTTTAAAGGTGTAAGCTTTGGTGAA
    GGATTTAAAGCAGCTGAAAAGCCAGGTAGTGAGATTCAAGATGAAATTCTATATAATAGT
    GAAATTGGTTATTATCGTGGATCTAATCATTTAGGTGGTTTAGAGGGTGGTATGTCAAAT
    GGTATGCCAATTATTGTAAATGGTGTAATGAAACCTATTCCTACGTTATATAAACCATTA
    AATTCAGTTGATATAAATACTAAAGAAGACTTTAAGGCAACAATTGAACGTTCTGATAGT
    TGTGCTGTACCTGCAGCAAGTATAGTGTGTGAACACGTTGTTGCATTTGAAATAGCGAAA
    GCATTACTTGAAGAGTTTCAATCAAACCATATTGAACAACTTCAACAACAAATTGCTGAC
    CGCAGACAATTAAATGTTGAGTTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1167

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_001451
  • symbol: AroC
  • description: chorismate synthase
  • length: 388
  • theoretical pI: 5.52122
  • theoretical MW: 42990.5
  • GRAVY: -0.371649

⊟Function[edit | edit source]

  • reaction:
    EC 4.2.3.5?  ExPASy
    Chorismate synthase 5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate
  • TIGRFAM:
    Metabolism Amino acid biosynthesis Aromatic amino acid family chorismate synthase (TIGR00033; EC 4.2.3.5; HMM-score: 405.8)
    and 1 more
    Unknown function Enzymes of unknown specificity archaeal radical SAM protein, PTO1314 family (TIGR03961; HMM-score: 12.6)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    no clan defined Chorismate_synt; Chorismate synthase (PF01264; HMM-score: 400.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9631
    • Cytoplasmic Membrane Score: 0.0004
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0364
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.01452
    • TAT(Tat/SPI): 0.000669
    • LIPO(Sec/SPII): 0.001711
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MRYLTSGESHGPQLTVIVEGIPANLEIKVEDINKEMFKRQGGYGRGRRMQIEKDTVEIVSGVRNGYTLGSPITMVVTNDDFTHWRKIMGAAPISEEERENMKRTITKPRPGHADLVGGMKYNHRDLRNVLERSSARETAARVAVGALCKVLLQQLDIDIYSRVVEIGGIKDKDFYDSETFKANLDRNDVRVIDDSIAQAMRDKIDEAKNEGDSIGGVVQVVVENMPVGVGSYVHYDRKLDGKIAQGVVSINAFKGVSFGEGFKAAEKPGSEIQDEILYNSEIGYYRGSNHLGGLEGGMSNGMPIIVNGVMKPIPTLYKPLNSVDINTKEDFKATIERSDSCAVPAASIVCEHVVAFEIAKALLEEFQSNHIEQLQQQIADRRQLNVEF

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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