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FunGene: 08-OCT-2024
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus JSNZ
- locus tag: JSNZ_001449
- pan locus tag?: SAUPAN003924000
- symbol: aroA
- pan gene symbol?: aroA
- synonym:
- product: 3-phosphoshikimate 1-carboxyvinyltransferase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: JSNZ_001449
- symbol: aroA
- product: 3-phosphoshikimate 1-carboxyvinyltransferase
- replicon: chromosome
- strand: -
- coordinates: 1496059..1497357
- length: 1299
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID:
- RefSeq:
- BioCyc:
- MicrobesOnline:
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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1261ATGGTAAATGAACAAATCATTGATATTTCAGGTCCGTTAAAGGGCGAAATAGAAGTGCCG
GGCGATAAGTCAATGACACACCGTGCAATCATGTTGGCGTCGCTAGCTGAAGGTGTATCT
ACTATATATAAGCCACTACTTGGCGAAGATTGTCGTCGTACGATGGACATTTTCCGACTG
TTAGGTGTAGAAATCAAAGAAGATGATGAAAAATTAGTTGTGACTTCCCCAGGATATCAA
TCTTTTAACACGCCACATCAAGTATTGTATACAGGTAATTCTGGTACGACAACACGATTA
TTAGCTGGTTTGTTAAGTGGTTTAGGTATTGAAAGTGTTTTGTCTGGCGATGTTTCAATT
GGTAAAAGGCCAATGGATCGTGTCTTGAGACCATTGAAACTTATGGATGCGAATATTGAA
GGTATTGAAGATAATTATACACCATTAATTATTAAGCCATCTGTCATAAAAGGTATAAAT
TATCAAATGGAAGTTGCAAGTGCACAAGTGAAAAGTGCCATTTTATTTGCAAGTTTGTTT
TCTAAGGAACCGACCATCATTAAAGAATTAGATGTAAGTCGAAATCATACTGAGACGATG
TTCAAACATTTTAATATTCCAATTGAAGCAGAAGGGTTATCAATAACTACAACCCCTGAT
GCCATTCAACATATTAAACCTGCAGATTTTCATGTTCCTGGCGATATTTCATCTGCAGCG
TTCTTTATTGTTGCAGCACTTATCACACCAGGAAGTGATGTAACAATTCATAATGTTGGA
ATCAATCCAACACGTTCAGGTATTATTGATATTGTTGAAAAAATGGGCGGTAATATCCAA
CTTTTCAATCAAACAACTGGTGCTGAACCTACTGCTTCTATTCGTATTCAATACACACCA
ATGCTTCAACCAATAACAATCGAAGGAGAATTAGTGCCAAAAGCAATTGATGAACTGCCT
GTAATAGCATTACTTTGTACACAAGCAGTTGGCACGAGTACAATTAAAGATGCCGAGGAA
TTAAAAGTAAAAGAAACAAATAGAATTGATACAACGGCTGATATGTTAAACTTGTTAGGG
TTTGAATTACAACCAACTAATGATGGATTGATTATTCATCCGTCAGAATTTAAAACAAAT
GCAACAGTTGATAGTTTAACTGATCATCGAATAGGAATGATGCTTGCAGTTGCTTCTCTA
CTTTCAAGCGAGCCTGTCAAAATCAAACAATTTGATGCTGTAAATGTATCATTTCCAGGA
TTTTTACCAAAACTAAAGCTTTTAGAAAATGAGGGATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: JSNZ_001449
- symbol: AroA
- description: 3-phosphoshikimate 1-carboxyvinyltransferase
- length: 432
- theoretical pI: 4.77214
- theoretical MW: 46921.8
- GRAVY: 0.0453704
⊟Function[edit | edit source]
- reaction: EC 2.5.1.19? ExPASy3-phosphoshikimate 1-carboxyvinyltransferase Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate
- TIGRFAM: Amino acid biosynthesis Aromatic amino acid family 3-phosphoshikimate 1-carboxyvinyltransferase (TIGR01356; EC 2.5.1.19; HMM-score: 379.4)and 1 moreCell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan UDP-N-acetylglucosamine 1-carboxyvinyltransferase (TIGR01072; EC 2.5.1.7; HMM-score: 74.8)
- TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
- PFAM: EPT_RTPC (CL0290) EPSP_synthase; EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) (PF00275; HMM-score: 448.7)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9978
- Cytoplasmic Membrane Score: 0.001
- Cell wall & surface Score: 0.0002
- Extracellular Score: 0.0009
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.004546
- TAT(Tat/SPI): 0.001018
- LIPO(Sec/SPII): 0.000446
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq:
- UniProt:
⊟Protein sequence[edit | edit source]
- MVNEQIIDISGPLKGEIEVPGDKSMTHRAIMLASLAEGVSTIYKPLLGEDCRRTMDIFRLLGVEIKEDDEKLVVTSPGYQSFNTPHQVLYTGNSGTTTRLLAGLLSGLGIESVLSGDVSIGKRPMDRVLRPLKLMDANIEGIEDNYTPLIIKPSVIKGINYQMEVASAQVKSAILFASLFSKEPTIIKELDVSRNHTETMFKHFNIPIEAEGLSITTTPDAIQHIKPADFHVPGDISSAAFFIVAALITPGSDVTIHNVGINPTRSGIIDIVEKMGGNIQLFNQTTGAEPTASIRIQYTPMLQPITIEGELVPKAIDELPVIALLCTQAVGTSTIKDAEELKVKETNRIDTTADMLNLLGFELQPTNDGLIIHPSEFKTNATVDSLTDHRIGMMLAVASLLSSEPVKIKQFDAVNVSFPGFLPKLKLLENEG
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- Operon-mapper [1] : JSNZ_001446 < JSNZ_001447 < JSNZ_001448 < aroA < aroB < aroC
⊟Regulation[edit | edit source]
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
Bioinformatics: 2018, 34(23);4118-4120
[PubMed:29931111] [WorldCat.org] [DOI] (I p) - ↑ Hannes Wolfgramm, Larissa Milena Busch, Jöran Tebben, Henry Mehlan, Lisa Hagenau, Thomas Sura, Tilly Hoffmüller, Elisa Bludau, Manuela Gesell Salazar, Alexander Reder, Stephan Michalik, Leif Steil, Kristin Surmann, Ulrike Mäder, Silva Holtfreter, Uwe Völker
Integrated genomic and proteomic analysis of the mouse-adapted Staphylococcus aureus strain JSNZ.
Curr Res Microb Sci: 2025, 9;100489
[PubMed:41146725] [WorldCat.org] [DOI] (I e)