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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000445
  • pan locus tag?: SAUPAN002246000
  • symbol: JSNZ_000445
  • pan gene symbol?: —
  • synonym:
  • product: MazG nucleotide pyrophosphohydrolase domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000445
  • symbol: JSNZ_000445
  • product: MazG nucleotide pyrophosphohydrolase domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 478209..479402
  • length: 1194
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGGCACATACCATTACGATTGTTGGCTTAGGAAACTATGGCATTGATGATTTGCCGCTA
    GGGATATATAAATTTTTAAAGACACAAGATAAAGTTTATGCAAGAACGTTAAATCATCCA
    GTTATAGAATCATTGCAAGATGAATTAACATTTCAGAGTTTTGACCATGTTTATGAAACA
    CATGACCAATTTGAAGATGTCTATAATGATATTGTGGCGCAATTGGTTGAAGCTGCTAAT
    GAAAAAGATATTGTCTATGCGGTTCCGGGTCATCCTAGAGTTGCTGAGACAACTACAGTG
    AAATTACTGGCTTTAGCAAAGGACAATACTGATATAGATGTGAAAGTTTTAGGTGGTAAA
    AGCTTTATTGATGATGTGTTTGAAGCAGTTAATGTAGATCCAAATGATGGCTTCACACTG
    TTAGATGCGACATCATTACAAGAAGTAACACTTAATGTTAGAACGCATACATTGATTACA
    CAAGTTTATAGTGCAATGGTTGCTGCTAATTTGAAAATCACTTTAATGGAACGATATCCT
    GATGATTACCCTGTTCAAATTGTCACTGGTGCACGAAGCGATGGTGCGGATAACGTTGTG
    ACATGCCCATTATATGAATTGGATCATGATGAAAATGCATTCAATAATTTGACGAGTGTA
    TTCGTACCAAAAATCATAACATCGACATATTTGTATCATGACTTTGATTTTGCAACGGAA
    GTGATTGATACTTTAGTTGATGAAGATAAAGGTTGTCCATGGGATAAAGTGCAAACGCAT
    GAAACGCTTAAGCGTTATTTACTTGAAGAAACATTTGAATTGTTCGAAGCTATTGACAAT
    GAAGATGATTGGCATATGATTGAAGAGCTAGGAGATATTTTATTACAAGTGTTATTGCAT
    ACTAGTATTGGTAAAAAAGAAGGGTATATCGACATTAAAGAAGTGATTACAAGTCTTAAT
    GCTAAAATGATTCGTAGACACCCACACATATTTGGTGATGCCAATGCTGAAACTATCGAT
    GACTTAAAAGAAATTTGGTCTAAGGCGAAAGATGCTGAAGGTAAACAGCCAAGAGTTAAA
    TTTGAAAAAGTATTTGCAGAGCATTTTTTAAATTTATATGAGAAGACGAAGGATAAGTCA
    TTTGATGAGGCCTCGTTAAAGCAGTGGCTAGAAAAAGGGGAGAGTAATACATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1194

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_000445
  • symbol: JSNZ_000445
  • description: MazG nucleotide pyrophosphohydrolase domain-containing protein
  • length: 397
  • theoretical pI: 4.36138
  • theoretical MW: 45156.4
  • GRAVY: -0.307809

⊟Function[edit | edit source]

  • TIGRFAM:
    Unknown function General MazG family protein (TIGR00444; HMM-score: 132.4)
    and 2 more
    Genetic information processing Protein fate Protein modification and repair diphthine synthase (TIGR00522; EC 2.1.1.98; HMM-score: 31.1)
    Unknown function Enzymes of unknown specificity encapsulated protein (TIGR04536; HMM-score: 13.5)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    MazG (CL0231) MazG; MazG nucleotide pyrophosphohydrolase domain (PF03819; HMM-score: 100.9)
    and 3 more
    no clan defined TP_methylase; Tetrapyrrole (Corrin/Porphyrin) Methylases (PF00590; HMM-score: 66.1)
    MazG (CL0231) PRA-PH; Phosphoribosyl-ATP pyrophosphohydrolase (PF01503; HMM-score: 14.9)
    MazG-like; MazG-like family (PF12643; HMM-score: 13.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9983
    • Cytoplasmic Membrane Score: 0.0005
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0011
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003015
    • TAT(Tat/SPI): 0.000119
    • LIPO(Sec/SPII): 0.000255
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MAHTITIVGLGNYGIDDLPLGIYKFLKTQDKVYARTLNHPVIESLQDELTFQSFDHVYETHDQFEDVYNDIVAQLVEAANEKDIVYAVPGHPRVAETTTVKLLALAKDNTDIDVKVLGGKSFIDDVFEAVNVDPNDGFTLLDATSLQEVTLNVRTHTLITQVYSAMVAANLKITLMERYPDDYPVQIVTGARSDGADNVVTCPLYELDHDENAFNNLTSVFVPKIITSTYLYHDFDFATEVIDTLVDEDKGCPWDKVQTHETLKRYLLEETFELFEAIDNEDDWHMIEELGDILLQVLLHTSIGKKEGYIDIKEVITSLNAKMIRRHPHIFGDANAETIDDLKEIWSKAKDAEGKQPRVKFEKVFAEHFLNLYEKTKDKSFDEASLKQWLEKGESNT

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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