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NCBI: 06-JUL-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_0468 [new locus tag: NWMN_RS02675 ]
  • pan locus tag?: SAUPAN002246000
  • symbol: NWMN_0468
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_0468 [new locus tag: NWMN_RS02675 ]
  • symbol: NWMN_0468
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 532689..533885
  • length: 1197
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    TTGATGGCACATACCATTACGATTGTTGGCTTAGGAAACTATGGCATTGATGATTTGCCG
    CTAGGGATATATAAATTTTTAAAGACACAAGATAAAGTTTATGCAAGAACGTTAGATCAT
    CCAGTTATAGAATCATTGCAAGATGAATTAACATTTCAGAGTTTTGACCATGTTTATGAA
    GCACATAACCAATTTGAAGATGTCTATATTGATATTGTGGCGCAATTGGTTGAAGCTGCT
    AATGAAAAAGATATTGTCTATGCGGTTCCGGGTCATCCTAGAGTTGCTGAGACAACTACA
    GTGAAATTACTGGCTTTAGCAAAGGACAATACTGATATAGATGTGAAAGTTTTAGGTGGG
    AAAAGCTTTATTGATGATGTGTTTGAAGCAGTTAATGTAGATCCAAATGATGGCTTCACA
    CTGTTAGATGCGACATCATTACAAGAAGTAACACTTAATGTTAGAACGCATACATTGATT
    ACGCAAGTTTATAGTGCAATGGTTGCTGCTAATTTGAAAATCACTTTAATGGAACGATAT
    CCTGATGATTACCCTGTTCAAATTGTCACTGGTGCACGAAGCGATGGTGCGGATAACGTT
    GTGACATGCCCATTATATGAATTGGATCATGATGAAAATGCATTCAATAATTTGACGAGT
    GTATTCGTACCAAAAATCATAACATCGACATATTTGTATCATGACTTTGATTTTGCAACG
    GAAGTGATTGATACTTTAGTTGATGAAGATAAAGGTTGTCCATGGGATAAAGTGCAAACG
    CATGAAACGCTAAAGCGTTATTTACTTGAAGAAACATTTGAATTGTTCGAAGCTATTGAC
    AATGAAGATGATTGGCATATGATTGAAGAACTAGGAGATATTTTATTACAAGTGTTATTG
    CATACTAGTATTGGTAAAAAAGAAGGGTATATCGACATTAAAGAAGTGATTACAAGTCTT
    AATGCTAAAATGATTCGTAGACACCCACACATATTTGGTGATGCCAATGCTGAAACTATC
    GATGACTTAAAAGAAATTTGGTCTAAGGCGAAAGATGCTGAAGGTAAACAGCCAAGAGTT
    AAATTTGAAAAAGTATTTGCAGAGCATTTTTTAAATTTATATGAGAAGACGAAGGATAAG
    TCATTTGATGAGGCCGCGTTAAAGCAGTGGCTAGAAAAAGGGGAGAGTAATACATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1197

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_0468 [new locus tag: NWMN_RS02675 ]
  • symbol: NWMN_0468
  • description: hypothetical protein
  • length: 398
  • theoretical pI: 4.36138
  • theoretical MW: 45240.7
  • GRAVY: -0.269347

Function[edit | edit source]

  • TIGRFAM:
    Unknown function General MazG family protein (TIGR00444; HMM-score: 132.3)
    and 1 more
    Genetic information processing Protein fate Protein modification and repair diphthine synthase (TIGR00522; EC 2.1.1.98; HMM-score: 30.3)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    MazG (CL0231) MazG; MazG nucleotide pyrophosphohydrolase domain (PF03819; HMM-score: 93.3)
    and 2 more
    no clan defined TP_methylase; Tetrapyrrole (Corrin/Porphyrin) Methylases (PF00590; HMM-score: 66.8)
    MazG (CL0231) MazG-like; MazG-like family (PF12643; HMM-score: 13)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005404
    • TAT(Tat/SPI): 0.000134
    • LIPO(Sec/SPII): 0.000427
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MMAHTITIVGLGNYGIDDLPLGIYKFLKTQDKVYARTLDHPVIESLQDELTFQSFDHVYEAHNQFEDVYIDIVAQLVEAANEKDIVYAVPGHPRVAETTTVKLLALAKDNTDIDVKVLGGKSFIDDVFEAVNVDPNDGFTLLDATSLQEVTLNVRTHTLITQVYSAMVAANLKITLMERYPDDYPVQIVTGARSDGADNVVTCPLYELDHDENAFNNLTSVFVPKIITSTYLYHDFDFATEVIDTLVDEDKGCPWDKVQTHETLKRYLLEETFELFEAIDNEDDWHMIEELGDILLQVLLHTSIGKKEGYIDIKEVITSLNAKMIRRHPHIFGDANAETIDDLKEIWSKAKDAEGKQPRVKFEKVFAEHFLNLYEKTKDKSFDEAALKQWLEKGESNT

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]