PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

FunGene: 08-OCT-2024

⊟Summary

• organism: Staphylococcus aureus JSNZ
• locus tag: JSNZ_000374
• pan locus tag^?: SAUPAN002146000
• symbol: JSNZ_000374
• pan gene symbol^?: —
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: JSNZ_000374
• symbol: JSNZ_000374
• product: hypothetical protein
• replicon: chromosome
• strand: +
• coordinates: 407220..408542
• length: 1323
• essential: unknown other strains

⊟Accession numbers

• Gene ID:
• RefSeq:
• BioCyc:
• MicrobesOnline:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  961
  1021
  1081
  1141
  1201
  1261
  1321
  
  ATGAGTAATAAATTTCGCTTAGATCATAGTTTTATAAATAATAAGACTGAGACAACTAGT
  GCAGTTTCTAAATTATCATATGAAATTGAAAATGCTAATCTCAATGGATTGCCAAAAACT
  AATTTGCAATTGCAGTTTGATAGATTAAAAGTAACTAATGAATTCCCTTCTAATCTTGAA
  TATATAGATAGTCACACAGATAAAAAGTACGGTGTGACAGCATCAGCTTTCTTAAACAAA
  GATACTGGGAAAGTGATTATTGGCATGACTGGAACAAACTTCAAAAAAGAAGCTCTTGCG
  AAGCAACTTTTGCTACCAGGGTTTGCAACAACAAAACAAGATAAAATTGACTCAGCTGAG
  ACTAGAAAGGATTTAATTTCCGATGTCCAAATTGGAACATTTCCTCCGTCTGATAAAAGC
  AAACATTATGAAGAAACACAAGAGTTCATCAAAAAAATAAAAAATAAGTATGATATTGAT
  TTTATTACTGGGCATTCATTAGGCGGTAGAGAAGCGGTAATATTAGGTATGAGTAATGGT
  ATTCCTAATATCGTTGTTTATAATCCAGCTCCCATATCAGCTATTGGCTTAGACCCTAAT
  TCTCGATTATTTAAATTATATAAAGGATATAAAGGTAACATTACTAGAGTTGTATCTAAT
  AAAGATGAGTTAACTAATTTTATTCAGGGATATACGAAATATGTTTATTTTGGACATGAG
  ATAGTGATTGAAAATGGTAAAGGTCATTCAATGGATGGATTCTTAACTGAACAAGAACAA
  AAAGCTATAAAAAAAGAACTTAAAAAACTACAAGGTTATGTAGAAGAAAATAATAAGTCA
  TTTGTAAAGCATTCTAATAATGCCATATCTAAATTAGCTAGTATAGAATTACTTAGAACA
  AATATGATGACTACAAATGGAGGTTGGTTATCTTCTTCGCAACAAAAAGCTTTAGAAAGT
  TTATCAGCTTTAACAATTGCGCAGTCATTCAGTCAACTGATAGATGATGAAATTAATCAA
  ATTAAAAAAATGTATAATGAAAAGGAAAAGAAATTTGAAAAAAATTGGGAAGACGCGCAA
  AAAGCTGGAAACGCTGTAGGTAAAGATATAACTGTGAGTGAAGTGCTAGAAGCTTTAGAT
  GAAGGTCATGTGAATGAAAGTAGTATGGTAGGAGATCCTGAACAAATGATATCTGCAAAA
  GAAAGACAACTTTCAACGATAGGGTCTTCTGTATCAAATTATATTCTAAGAGTTAGATCT
  AGTATTAATGAAATCGTTGATAAAGATCAAGTGCTTGCATCACAAATAGGTGGATTACTA
  TGA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  780
  840
  900
  960
  1020
  1080
  1140
  1200
  1260
  1320
  1323
  

⊟Protein

⊟General

• locus tag: JSNZ_000374
• symbol: JSNZ_000374
• description: hypothetical protein
• length: 440
• theoretical pI: 7.90119
• theoretical MW: 49118.3
• GRAVY: -0.511591

⊟Function

• TIGRFAM:
  Metabolism Energy metabolism Other tetrahydromethanopterin S-methyltransferase, subunit G (TIGR01149; EC 2.1.1.86; HMM-score: 16.4)
  Cellular processes Cellular processes Detoxification S-formylglutathione hydrolase (TIGR02821; EC 3.1.2.12; HMM-score: 13.8)
  Metabolism Fatty acid and phospholipid metabolism Degradation esterase, PHB depolymerase family (TIGR01840; EC 3.1.1.-; HMM-score: 13.4)
• TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
• PFAM:
  AB_hydrolase (CL0028) Lipase_3; Lipase (class 3) (PF01764; HMM-score: 17.2)
  UPF0227; Uncharacterised protein family (UPF0227) (PF05728; HMM-score: 16.9)
  AlbA (CL0441) SLFN_AlbA_2; Schlafen, AlbA_2 (PF04326; HMM-score: 14.8)
  AB_hydrolase (CL0028) Abhydrolase_11; Alpha/beta hydrolase domain (PF20408; HMM-score: 14.4)
  NADP_Rossmann (CL0063) MOLO1; Modulator of levamisole receptor-1 (PF17175; HMM-score: 14.2)
  and 6 more
  no clan defined MtrG; Tetrahydromethanopterin S-methyltransferase, subunit G (PF04210; HMM-score: 12.7)
  Perilipin_sf (CL0718) Perilipin; Perilipin family (PF03036; HMM-score: 12.3)
  Apolipoprotein (CL0725) Apo-CIII; Apolipoprotein CIII (Apo-CIII) (PF05778; HMM-score: 11.3)
  no clan defined AbiH; Bacteriophage abortive infection AbiH (PF14253; HMM-score: 11.2)
  DUF3574; Protein of unknown function (DUF3574) (PF12098; HMM-score: 10.1)
  Wx5_PLAF3D7; Protein of unknown function (Wx5_PLAF3D7) (PF09688; HMM-score: 8.1)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: unknown (no significant prediction)
  • Cytoplasmic Score: 2.5
  • Cytoplasmic Membrane Score: 2.5
  • Cellwall Score: 2.5
  • Extracellular Score: 2.5
  • Internal Helices: 0
• DeepLocPro: Extracellular
  • Cytoplasmic Score: 0.0001
  • Cytoplasmic Membrane Score: 0.0001
  • Cell wall & surface Score: 0.0005
  • Extracellular Score: 0.9993
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.006703
  • TAT(Tat/SPI): 0.000911
  • LIPO(Sec/SPII): 0.001172
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq:
• UniProt:

⊟Protein sequence

• MSNKFRLDHSFINNKTETTSAVSKLSYEIENANLNGLPKTNLQLQFDRLKVTNEFPSNLEYIDSHTDKKYGVTASAFLNKDTGKVIIGMTGTNFKKEALAKQLLLPGFATTKQDKIDSAETRKDLISDVQIGTFPPSDKSKHYEETQEFIKKIKNKYDIDFITGHSLGGREAVILGMSNGIPNIVVYNPAPISAIGLDPNSRLFKLYKGYKGNITRVVSNKDELTNFIQGYTKYVYFGHEIVIENGKGHSMDGFLTEQEQKAIKKELKKLQGYVEENNKSFVKHSNNAISKLASIELLRTNMMTTNGGWLSSSQQKALESLSALTIAQSFSQLIDDEINQIKKMYNEKEKKFEKNWEDAQKAGNAVGKDITVSEVLEALDEGHVNESSMVGDPEQMISAKERQLSTIGSSVSNYILRVRSSINEIVDKDQVLASQIGGLL

⊟Experimental data

• experimentally validated: data available for COL, NCTC8325
• protein localization: data available for COL
• quantitative data / protein copy number per cell: data available for COL
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications