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⊟Summary[edit | edit source]
- pan ID?: SAUPAN002146000
- symbol?: —
- synonym:
- description?: membrane protein
- membrane protein
- lipase family protein
- pseudogene
descriptions from strain specific annotations:
- strand?: +
- coordinates?: 2653297..2662055
- synteny block?: BlockID0014520
- occurrence?: in 85% of 34 strains
tslA : type VIIb-secreted phospholipase toxin TslA [1]
⊟Orthologs[edit | edit source]
04-02981:
SA2981_0422
08BA02176:
—
11819-97:
MS7_0420
6850:
RSAU_000376
71193:
—
ECT-R 2:
ECTR2_381
ED133:
SAOV_0459
ED98:
SAAV_0389
HO 5096 0412:
SAEMRSA15_03710
JH1:
SaurJH1_0481
JH9:
SaurJH9_0469
JKD6008:
SAA6008_00449
JKD6159:
—
LGA251:
SARLGA251_03810
M013:
M013TW_0409
MRSA252:
SAR0446
MSHR1132:
—
MSSA476:
SAS0404
Mu3:
SAHV_0444
Mu50:
SAV0446
MW2:
MW0402
RF122:
SAB0397
ST398:
—
T0131:
SAT0131_00484
TCH60:
HMPREF0772_10076
TW20:
SATW20_05150
USA300_TCH1516:
USA300HOU_0448
VC40:
SAVC_01825
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 | |
| JSNZ |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL -MSRKYKIDLKAINQNTESTSAISKASYEVENANNNGLSKRDVINQFNDLKKMKKFPSNL
N315 -MKDKYKIDPGIIKNNTEETTAISKISYEVENANLYGADSEDITRQIEYLKAKKKFPSNL
NCTC8325 MLSRKYKIDLKAINQNTESTSAISKASYEVENANNNGLSKRDVINQFNDLKKMKKFPSNL
Newman MLSRKYKIDLKAINQNTESTSAISKASYEVENANNNGLSKRDVINQFNDLKKMKKFPSNL
USA300_FPR3757 MLSRKYKIDLKAINQNTESTSAISKASYEVENANNNGLSKRDVINQFNDLKKMKKFPSNL
:. ***** *::***.*:**** ******** * ...*: .*:: ** *******
COL EYVDSYTDSLTGVTTSAFLNKDTGKVTLGMTGTNLQDEAFKKLKEGEFSRQNVTNALETV
N315 EYVDSYTDSLNGVTTSAFLNKDTGKVTLGMTGTNIQGEAFKKLKEGEFSRQNVTNALETV
NCTC8325 EYVDSYTDSLTGVTTSAFLNKDTGKVTLGMTGTNLQDEAFKKLKEGEFSRQNVTNALETV
Newman EYVDSYTDSLTGVTTSAFLNKDTGKVTLGMTGTNLQDEAFKKLKEGEFSRQNVTNALETV
USA300_FPR3757 EYVDSYTDSLTGVTTSAFLNKDTGKVTLGMTGTNLQDEAFKKLKEGEFSRQNVTNALETV
**********.***********************:*.***********************
COL KDGYADLKILYSPASDQNYRYANTQEFINKIKSKYDIDFITGHSLGGRDAVVLGMSNGIP
N315 KDGYADLKILYSPASDQNYRYANTQEFINKIKSKYDIDFITGHSLGGRDAVVLGMSNGIP
NCTC8325 KDGYADLKILYSPASDQNYRYANTQEFINKIKSKYDIDFITGHSLGGRDAVVLGMSNGIP
Newman KDGYADLKILYSPASDQNYRYANTQEFINKIKSKYDIDFITGHSLGGRDAVVLGMSNGIP
USA300_FPR3757 KDGYADLKILYSPASDQNYRYANTQEFINKIKSKYDIDFITGHSLGGRDAVVLGMSNGIP
************************************************************
COL NIVVYNPAPISITSLNPNSPDGKRLLELYKNYKGNITRFVAENDALTENLKKYKHYVFFG
N315 NIVVYNPAPISINSLNPNSPDGKRLLELYKNYKGNITRFVAENDALTENLKKYKHYVFFG
NCTC8325 NIVVYNPAPISITSLNPNSPDGKRLLELYKNYKGNITRFVAENDALTENLKKYKHYVFFG
Newman NIVVYNPAPISITSLNPNSPDGKRLLELYKNYKGNITRFVAENDALTENLKKYKHYVFFG
USA300_FPR3757 NIVVYNPAPISITSLNPNSPDGKRLLELYKNYKGNITRFVAENDALTENLKKYKHYVFFG
************.***********************************************
COL NDKVFKNGKGHEMEGFLTEEEQKAIKKELKKLQGYAEENNKSFVKNSNNAISKLASIELL
N315 NDKVFKNGKGHEMEGFLTEEEQKAIKKELKKLQGYAEENNKSFVKNSNNAISKLASIELL
NCTC8325 NDKVFKNGKGHEMEGFLTEEEQKAIKKELKKLQGYAEENNKSFVKNSNNAISKLASIELL
Newman NDKVFKNGKGHEMEGFLTEEEQKAIKKELKKLQGYAEENNKSFVKNSNNAISKLASIELL
USA300_FPR3757 NDKVFKNGKGHEMEGFLTEEEQKAIKKELKKLQGYAEENNKSFVKNSNNAISKLASIELL
************************************************************
COL RANMMTTNGGGLSSSQQKVLESLTALTIAQSFSQLIDDEINQIKKMYNEKKKKFGKNWED
N315 RANMMTTNGGGLSSSQQKVLESLTALTIAQSFSQLIDDEINQIKKMYNEKKKEFGKNWED
NCTC8325 RANMMTTNGGGLSSSQQKVLESLTALTIAQSFSQLIDDEINQIKKMYNEKKKKFGKNWED
Newman RANMMTTNGGGLSSSQQKVLESLTALTIAQSFSQLIDDEINQIKKMYNEKKKKFGKNWED
USA300_FPR3757 RANMMTTNGGGLSSSQQKVLESLTALTIAQSFSQLIDDEINQIKKMYNEKKKKFGKNWED
****************************************************:*******
COL AQKAGKAVGEDLSVNGVLNALDEGQVNESSMVREPEQMISAKERQLSTIGSSVSNYIMRV
N315 AQKAGKAVGEDLSVNGVLNALDEGQVNESSMVREPEQMISAKERQLSTIGSSVSNYIMRV
NCTC8325 AQKAGKAVGEDLSVNGVLNALDEGQVNESSMVREPEQMISAKERQLSTIGSSVSNYIMRV
Newman AQKAGKAVGEDLSVNGVLNALDEGQVNESSMVREPEQMISAKERQLSTIGSSVSNYIMRV
USA300_FPR3757 AQKAGKAVGEDLSVNGVLNALDEGQVNESSMVREPEQMISAKERQLSTIGSSVSNYIMRV
************************************************************
COL RLSINEIVDKDQVLASQIGGLL
N315 RLSINEIVDKDQVLASQIGGLL
NCTC8325 RLSINEIVDKDQVLASQIGGLL
Newman RLSINEIVDKDQVLASQIGGLL
USA300_FPR3757 RLSINEIVDKDQVLASQIGGLL
**********************
- ↑ Stephen R Garrett, Nicole Mietrach, Justin Deme, Alina Bitzer, Yaping Yang, Fatima R Ulhuq, Dorothee Kretschmer, Simon Heilbronner, Terry K Smith, Susan M Lea, Tracy Palmer
A type VII-secreted lipase toxin with reverse domain arrangement.
Nat Commun: 2023, 14(1);8438
[PubMed:38114483] [WorldCat.org] [DOI] (I e)