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NCBI: 26-AUG-2013

⊟Summary[edit | edit source]

organism: Staphylococcus aureus N315

locus tag: SA1918 [new locus tag: SA_RS11030 ]

pan locus tag^?: SAUPAN005407000

symbol: SA1918

pan gene symbol^?: —

synonym:
product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

type: CDS
locus tag: SA1918 [new locus tag: SA_RS11030 ]
symbol: SA1918
product: hypothetical protein
replicon: chromosome
strand: -
coordinates: 2166362..2167408
length: 1047
essential: no DEG other strains

⊟Accession numbers[edit | edit source]

Gene ID: 1124819 NCBI
RefSeq: NP_375223 NCBI
BioCyc: see SA_RS11030
MicrobesOnline: 104249 MicrobesOnline

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

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1021
TTGGATACTAAAATTTGGGATGTTAGAGAATATAATGAAGATTTACAGCAATATCCTAAA
ATTAATGAAATAAAAGACATTGTTTTAAACGGTGGTTTAATAGGTTTACCAACTGAAACA
GTTTATGGACTTGCAGCAAATGCGACAGATGAAGAAGCTGTAGCTAAAATATATGAAGCT
AAAGGCCGTCCATCTGACAATCCGCTTATTGTTCATATACACAGTAAAGTTCAATTAAAA
GATTTTACATATACTTTGGATCCACGCGTAGAAAAGTTAATGCAGGCATTCTGGCCGGGC
CCTATTTCGTTTATATTGCCGCTAAAGCCAGGCTATCTATGTCGAAAAGTTTCTGGAGGT
TTATCATCAGTTGCTGTTAGAATGCCAAGCCATTCTGTAGGTAGACAATTATTACAAATC
ATAAATGAACCTCTAGCTGCTCCAAGTGCTAATTTAAGTGGTAGACCTTCACCAACAACT
TTCAATCATGTATATCAAGATTTGAATGCCCGTATAGATGGTATTGTTCAAGCTGAACAA
AGTGAAGAAGGATTAGAAAGTACGGTTTTAGATTGCACATCTTTTCCTTATAAAATTGCA
AGACCTGGTTCTATAACAGCAGCAATGATTACAGAAATACTTCCGAATAGTATCGCCCAT
GCTGATTATAATGATACTGAACAGCCAATTGCACCAGGTATGAAGTATAAGCATTACTCA
CCCAATACACCACTTACAATTATTACAGATATTGAGAGCAAAATTGGAAATGACGGTAAA
GATTGGTCTTCTATAGCTTTTATTGTGCCGAGTAATAAGGTGGCGTTTATACCAAGTGAA
GCGCAATTCATTCAATTATGTCAGGATGACAATGATGTTAAACAAGCAAGTCATAATCTT
TATGATGTGTTACATTCACTTGATGAAAATGAAAATATTTCAGCGGCGTATATATACGGC
TTTGAGCTGAATGATAATACAGAAGCAATTATGAATCGCATGTTAAAAGCTGCAGGTAAT
CACATTATTAAAGGATGTGAACTATGA
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1047

⊟Protein[edit | edit source]

⊟General[edit | edit source]

locus tag: SA1918 [new locus tag: SA_RS11030 ]
symbol: SA1918
description: hypothetical protein
length: 348
theoretical pI: 4.80011
theoretical MW: 38485.3
GRAVY: -0.26523

⊟Function[edit | edit source]

⊞reaction:
EC 2.7.7.87? ExPASy
L-threonylcarbamoyladenylate synthase L-threonine + ATP + HCO₃(-) = L-threonylcarbamoyladenylate + diphosphate + H₂O
⊞TIGRFAM:
Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family (TIGR00057; HMM-score: 195.4)
and 1 more
Genetic information processing Protein fate Protein modification and repair carbamoyltransferase HypF (TIGR00143; HMM-score: 25.4)
⊞
TheSEED :
- SUA5 domain fused to TsaC
- Threonylcarbamoyl-AMP synthase (EC 2.7.7.87)
RNA Metabolism RNA processing and modification YrdC-YciO TsaC protein (YrdC-Sua5 domains) required for threonylcarbamoyladenosine t(6)A37 modification in tRNA
and 1 more
RNA Metabolism RNA processing and modification YrdC-YciO-Sua5 and associated protein families TsaC protein (YrdC-Sua5 domains) required for threonylcarbamoyladenosine t(6)A37 modification in tRNA
⊞PFAM:
no clan defined Sua5_yciO_yrdC; Telomere recombination (PF01300; HMM-score: 193.3)
and 1 more
GT-B (CL0113) Sua5_C; Threonylcarbamoyl-AMP synthase, C-terminal domain (PF03481; HMM-score: 90.7)

⊟Structure, modifications & cofactors[edit | edit source]

domains:
modifications:
cofactors:
effectors:

⊟Localization[edit | edit source]

⊞
PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
⊞
DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9841
- Cytoplasmic Membrane Score: 0.0024
- Cell wall & surface Score: 0.0004
- Extracellular Score: 0.0131
⊞
LocateP: Intracellular
- Prediction by SwissProt Classification: Cytoplasmic
- Pathway Prediction: No pathway
- Intracellular possibility: 1
- Signal peptide possibility: -1
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: No CleavageSite
⊞
SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.041162
- TAT(Tat/SPI): 0.011825
- LIPO(Sec/SPII): 0.000612
predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

GI: 15927690 NCBI
RefSeq: NP_375223 NCBI
UniProt: A0A0H3JM49 UniProt

⊟Protein sequence[edit | edit source]

MDTKIWDVREYNEDLQQYPKINEIKDIVLNGGLIGLPTETVYGLAANATDEEAVAKIYEAKGRPSDNPLIVHIHSKVQLKDFTYTLDPRVEKLMQAFWPGPISFILPLKPGYLCRKVSGGLSSVAVRMPSHSVGRQLLQIINEPLAAPSANLSGRPSPTTFNHVYQDLNARIDGIVQAEQSEEGLESTVLDCTSFPYKIARPGSITAAMITEILPNSIAHADYNDTEQPIAPGMKYKHYSPNTPLTIITDIESKIGNDGKDWSSIAFIVPSNKVAFIPSEAQFIQLCQDDNDVKQASHNLYDVLHSLDENENISAAYIYGFELNDNTEAIMNRMLKAAGNHIIKGCEL

⊟Experimental data[edit | edit source]

experimentally validated: data available for COL, NCTC8325
protein localization: data available for COL
quantitative data / protein copy number per cell: data available for COL
interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

MicrobesOnline: SA1917 < SA1918 < SA1919 < prfA < tdk

⊟Regulation[edit | edit source]

regulator:

⊟Transcription pattern[edit | edit source]

S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

Aureolib: no data available

⊟Protein stability[edit | edit source]

half-life: no data available

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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