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NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus N315
- locus tag: SA_RS08500 [old locus tag: SA1509 ]
- pan locus tag?: SAUPAN004308000
- symbol: SA_RS08500
- pan gene symbol?: nrdR
- synonym:
- product: transcriptional regulator NrdR
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
⊟Accession numbers[edit | edit source]
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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421ATGAAATGCCCGAAATGTAATTCTACACAATCTAAAGTTGTAGATTCAAGGCATGCCGAT
GAATTAAATGCCATTCGAAGACGAAGAGAATGTGAAAATTGTGGAACACGTTTCACTACA
TTTGAACATATCGAAGTTAGTCAGCTTATAGTTGTGAAAAAAGATGGCACAAGAGAGCAG
TTTTCAAGAGAAAAAATACTTAATGGACTTGTGCGTTCTTGTGAGAAACGACCAGTTAGA
TATCAACAACTTGAAGACATAACAAACAAGGTTGAATGGCAATTACGAGATGAAGGTCAT
ACGGAAGTGTCTTCACGAGATATAGGTGAACACGTTATGAACTTGTTAATGCATGTTGAT
CAAGTTTCATATGTTAGATTTGCATCAGTCTATAAAGAATTTAAAGATGTTGATCAATTG
TTAGCATCGATGCAAGGGATTTTAAGCGAAAACAAACGGAGTGATGCTTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SA_RS08500 [old locus tag: SA1509 ]
- symbol: SA_RS08500
- description: transcriptional regulator NrdR
- length: 156
- theoretical pI: 7.89688
- theoretical MW: 18203.5
- GRAVY: -0.744872
⊟Function[edit | edit source]
- TIGRFAM: Regulatory functions DNA interactions transcriptional regulator NrdR (TIGR00244; HMM-score: 187.7)and 4 moreCys-rich peptide, TIGR04165 family (TIGR04165; HMM-score: 16.4)Regulatory functions DNA interactions putative regulatory protein, FmdB family (TIGR02605; HMM-score: 14.6)MJ0042 family finger-like domain (TIGR02098; HMM-score: 12)cxxc_20_cxxc protein (TIGR04104; HMM-score: 8.7)
- TheSEED: see SA1509
- PFAM: no clan defined ATP-cone; ATP cone domain (PF03477; HMM-score: 65.1)and 11 moreC2H2-zf (CL0361) zf-DBF; DBF zinc finger (PF07535; HMM-score: 19.1)Zn_Beta_Ribbon (CL0167) TF_Zn_Ribbon; TFIIB zinc-binding (PF08271; HMM-score: 16.3)Zn_Tnp_IS1595; Transposase zinc-ribbon domain (PF12760; HMM-score: 15.4)Zn-ribbon_8; Zinc ribbon domain (PF09723; HMM-score: 14.6)zinc_ribbon_5; zinc-ribbon domain (PF13719; HMM-score: 14.1)zf-FYVE-PHD (CL0390) FYVE; FYVE zinc finger (PF01363; HMM-score: 14)Zn_Beta_Ribbon (CL0167) Elf1; Transcription elongation factor Elf1 like (PF05129; HMM-score: 13.8)TFIIS_C; Transcription factor S-II (TFIIS) (PF01096; HMM-score: 12.2)C2H2-zf (CL0361) zf-C2H2; Zinc finger, C2H2 type (PF00096; HMM-score: 11.1)Zn_Beta_Ribbon (CL0167) zinc_ribbon_2; zinc-ribbon domain (PF13240; HMM-score: 8.7)zinc_ribbon_4; zinc-ribbon domain (PF13717; HMM-score: 8.6)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors: Zn2+
- effectors:
- genes regulated by NrdR, TF important in Deoxyribonucleotide biosynthesis: see SA1509
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.016516
- TAT(Tat/SPI): 0.00067
- LIPO(Sec/SPII): 0.005624
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MKCPKCNSTQSKVVDSRHADELNAIRRRRECENCGTRFTTFEHIEVSQLIVVKKDGTREQFSREKILNGLVRSCEKRPVRYQQLEDITNKVEWQLRDEGHTEVSSRDIGEHVMNLLMHVDQVSYVRFASVYKEFKDVDQLLASMQGILSENKRSDA
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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