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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

organism: Staphylococcus aureus USA300_FPR3757
locus tag: SAUSA300_RS11400 [old locus tag: SAUSA300_2070 ]
pan locus tag^?: SAUPAN005407000
symbol: SAUSA300_RS11400
pan gene symbol^?: —
synonym:
product: threonylcarbamoyl-AMP synthase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

type: CDS
locus tag: SAUSA300_RS11400 [old locus tag: SAUSA300_2070 ]
symbol: SAUSA300_RS11400
product: threonylcarbamoyl-AMP synthase
replicon: chromosome
strand: -
coordinates: 2231704..2232801
length: 1098
essential: unknown other strains

⊟Accession numbers[edit | edit source]

Location: NC_007793 (2231704..2232801) NCBI
BioCyc: SAUSA300_RS11400 BioCyc
MicrobesOnline: see SAUSA300_2070

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

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GTGCATAGCTTTTTGCTTTATATTATGATAAATAAGAAAGGCGTGATTAAGTTGGATACT
AAAATTTGGGATGTTAGAGAATATAATGAAGATTTACAGCAATATCCTAAAATTAATGAA
ATAAAAGACATTGTTTTAAACGGTGGTTTAATAGGTTTACCAACTGAAACAGTTTATGGA
CTTGCAGCAAATGCGACAGATGAAGAAGCTGTAGCTAAAATATATGAAGCTAAAGGCCGT
CCATCTGACAATCCGCTTATTGTTCATATACACAGTAAAGGTCAATTAAAAGATTTTACA
TATACTTTGGATCCACGCGTAGAAAAGTTAATGCAGGCATTCTGGCCGGGCCCTATTTCG
TTTATATTGCCGTTAAAGCTAGGCTATCTATGTCGAAAAGTTTCTGGAGGTTTATCATCA
GTTGCTGTTAGAATGCCAAGCCATTCTGTAGGTAGACAATTATTACAAATCATAAATGAA
CCTCTAGCTGCTCCAAGTGCTAATTTAAGTGGTAGACCTTCACCAACAACTTTCAATCAT
GTATATCAAGATTTGAATGGCCGTATCGATGGTATTGTTCAAGCTGAACAAAGTGAAGAA
GGATTAGAAAGTACGGTTTTAGATTGCACATCTTTTCCTTATAAAATTGCAAGACCTGGT
TCTATAACAGCAGCAATGATTACAGAAATACTTCCGAATAGTATCGCCCATGCTGATTAT
AATGATACTGAACAGCCAATTGCACCAGGTATGAAGTATAAGCATTACTCACCCAATACA
CCACTTACAATTATTACAGATATTGAGAGCAAAATTGGAAATGACGGTAAAGATTGGTCT
TCTATAGCTTTTATTGTGCCGAGTAATAAGGTGGCGTTTATACCAAGTGAAGCGCAATTC
ATTCAATTATGTCAGGATGACAATGATGTTAAACAAGCAAGTCATAATCTTTATGATGTG
TTACATTCACTTGATGAAAATGAAAATATTTCAGCGGCGTATATATACGGCTTTGAGCTG
AATGATAATACAGAAGCAATTATGAATCGCATGTTAAAAGCTGCAGGTAATCACATTATT
AAAGGATGTGAACTATGA
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⊟Protein[edit | edit source]

⊟General[edit | edit source]

locus tag: SAUSA300_RS11400 [old locus tag: SAUSA300_2070 ]
symbol: SAUSA300_RS11400
description: threonylcarbamoyl-AMP synthase
length: 365
theoretical pI: 5.23175
theoretical MW: 40444.8
GRAVY: -0.22137

⊟Function[edit | edit source]

reaction:
EC 2.7.7.87? ExPASy
L-threonylcarbamoyladenylate synthase L-threonine + ATP + HCO₃(-) = L-threonylcarbamoyladenylate + diphosphate + H₂O
TIGRFAM:
Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family (TIGR00057; HMM-score: 194.3)
and 1 more
Genetic information processing Protein fate Protein modification and repair carbamoyltransferase HypF (TIGR00143; HMM-score: 27.2)
TheSEED: see SAUSA300_2070
PFAM:
no clan defined Sua5_yciO_yrdC; Telomere recombination (PF01300; HMM-score: 179.2)
and 1 more
GT-B (CL0113) SUA5; Putative GTP-binding controlling metal-binding (PF03481; HMM-score: 76.3)

⊟Structure, modifications & cofactors[edit | edit source]

domains:
modifications:
cofactors:
effectors:

⊟Localization[edit | edit source]

PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
LocateP:
SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.004616
- TAT(Tat/SPI): 0.000177
- LIPO(Sec/SPII): 0.000577
predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

GI: see SAUSA300_2070
RefSeq: WP_011447046 NCBI
UniProt: see SAUSA300_2070

⊟Protein sequence[edit | edit source]

MHSFLLYIMINKKGVIKLDTKIWDVREYNEDLQQYPKINEIKDIVLNGGLIGLPTETVYGLAANATDEEAVAKIYEAKGRPSDNPLIVHIHSKGQLKDFTYTLDPRVEKLMQAFWPGPISFILPLKLGYLCRKVSGGLSSVAVRMPSHSVGRQLLQIINEPLAAPSANLSGRPSPTTFNHVYQDLNGRIDGIVQAEQSEEGLESTVLDCTSFPYKIARPGSITAAMITEILPNSIAHADYNDTEQPIAPGMKYKHYSPNTPLTIITDIESKIGNDGKDWSSIAFIVPSNKVAFIPSEAQFIQLCQDDNDVKQASHNLYDVLHSLDENENISAAYIYGFELNDNTEAIMNRMLKAAGNHIIKGCEL

⊟Experimental data[edit | edit source]

experimentally validated: data available for COL, NCTC8325
protein localization: data available for COL
quantitative data / protein copy number per cell: data available for COL
interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

regulator:

⊟Transcription pattern[edit | edit source]

S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

Aureolib: no data available

⊟Protein stability[edit | edit source]

half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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