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NCBI: 26-AUG-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA0480 [new locus tag: SA_RS02825 ]
  • pan locus tag?: SAUPAN002287000
  • symbol: ctsR
  • pan gene symbol?: ctsR
  • synonym:
  • product: hypothetical protein

⊟Additional information (user-provided)[edit | edit source]

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA0480 [new locus tag: SA_RS02825 ]
  • symbol: ctsR
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 560629..561090
  • length: 462
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGCACAATATGTCTGACATCATAGAACAATACATCAAACGTTTATTTGAAGAGTCGAAT
    GAAGATGTCGTTGAAATTCAGAGAGCGAATATCGCACAGCGTTTTGATTGTGTACCATCA
    CAATTAAATTATGTAATCAAAACACGATTCACTAATGAACATGGTTATGAAATCGAAAGT
    AAACGTGGTGGTGGTGGTTACATCCGAATCACTAAAATTGAAAATAAAGATGCAACAGGT
    TATATTAATCATTTGCTTCAGCTGATTGGACCTTCTATTTCTCAACAACAAGCTTATTAT
    ATTATTGATGGGCTTTTAGATAAAATGTTAATAAATGAACGTGAAGCTAAAATGATTCAA
    GCAGTTATTGATAGAGAAACGCTATCAATGGATATGGTTTCTAGAGATATTATTAGAGCA
    AATATTTTAAAACGTTTGTTACCAGTTATAAATTATTACTAA
    60
    120
    180
    240
    300
    360
    420
    462


⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA0480 [new locus tag: SA_RS02825 ]
  • symbol: CtsR
  • description: hypothetical protein
  • length: 153
  • theoretical pI: 6.26841
  • theoretical MW: 17841.4
  • GRAVY: -0.333333

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • Transcriptional regulator CtsR
  • PFAM:
    HTH (CL0123) CtsR; CtsR N-terminal HTH domain (PF05848; HMM-score: 123.3)
    and 2 more
    no clan defined CtsR_C; CtsR C-terminal dimerization domain (PF17727; HMM-score: 81.7)
    HTH (CL0123) CENP-B_N; CENP-B N-terminal DNA-binding domain (PF04218; HMM-score: 13)

⊟Structure, modifications & cofactors[edit | edit source]

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.8314
    • Cytoplasmic Membrane Score: 0.0998
    • Cell wall & surface Score: 0.0009
    • Extracellular Score: 0.0679
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006698
    • TAT(Tat/SPI): 0.000733
    • LIPO(Sec/SPII): 0.000878
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MHNMSDIIEQYIKRLFEESNEDVVEIQRANIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQAYYIIDGLLDKMLINEREAKMIQAVIDRETLSMDMVSRDIIRANILKRLLPVINYY

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: CtsR (repression) regulon
    CtsR(TF)important in Heat shock response; RegPrecise 

⊟Additional information (user-provided)[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟Other information (user-provided)[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]


⊟Relevant publications[edit | edit source]

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