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NCBI: 06-JUL-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus Newman
- locus tag: NWMN_0786 [new locus tag: NWMN_RS04445 ]
- pan locus tag?: SAUPAN002895000
- symbol: sufD
- pan gene symbol?: sufD
- synonym:
- product: FeS assembly protein SufD
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: NWMN_0786 [new locus tag: NWMN_RS04445 ]
- symbol: sufD
- product: FeS assembly protein SufD
- replicon: chromosome
- strand: +
- coordinates: 875281..876588
- length: 1308
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 5332519 NCBI
- RefSeq: YP_001331820 NCBI
- BioCyc:
- MicrobesOnline: 3706335 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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1261ATGACAACTGATATTTTGAACATTTCTGAAGAACAACTTGTTGATTATTCTAAAGCCCAC
AATGAACCTTCTTGGATGACAGAATTACGTAAAAAAGCTTTGAAATTAACAGAAACTTTA
GAAATGCCAAAACCTGATAAAACAAAATTAAGAAAATGGGATTTTGATTCTTTTAAACAA
CACGATGTAAAAGGTGATGTTTATCAATCTTTATCACAATTACCTGAGTCAGTAAGAGAA
ATTATTGACGTAGATCATTCTAAAAACTTAGTAATTCAACATAATAATACGATTGCGTAC
ACACAAGTTGATGATAATGCATCGAAAGATGGCGTTATCGTTGAAGGTTTAGCAGACGCT
CTTATGAACCATAGTGATTTAGTACAAAAGTACTTTATGAAAGATGCAGTAACAGTAGAT
GAACATCGTATCACAGCGCTACACACGGCATTAGTTAATGGTGGCGTATTTGTTTATGTT
CCTAAAAATGTAGTTGTAGAACATCCAGTACAATACGTTGTGTTGCACGACGACGAAAAT
GCAAGCTTTTATAACCATGTTATCATCGTTACTGAAGAAAGCGCCGAAGTCACATATGTT
GAAAATTACTTATCAAATGCATCTGGTGAAGGAAATCAATTAAATATTATTTCTGAAGTG
ATTGCTGGTGCAAATTCAAATATCACATATGGCTCAGTGGACTATATGGATAAAGGCTTT
ACAGGTCATATCATTCGACGTGGTATTACTGAAGCGGATGCCTCAATTAATTGGGCACTA
GGTTTAATGAATGAGGGTAGCCAAATTATTGATAATACAACAAATTTATTTGGTGATCGT
TCAACAAGTTCACTTAAATCAGTAGTTGTAGGTACAGGCGAACAAAAAATTAATCTAACA
TCTAAAATCGTACAATATGGTAAAGAAACAGATGGTTATATCCTTAAACATGGTGTTATG
AAAGAACATGCATCGTCTGTATTTAATGGTATCGGCTACATTAAGCATGGTGGAACTAAA
TCAATTGCTAATCAGGAATCACGTGTATTAATGTTATCTGAACATGCTCGTGGTGACGCG
AATCCTATTTTATTAATTGATGAAGATGATGTACAAGCTGGTCATGCTGCATCAGTAGGT
CGTGTTGATCCAGATCAACTTTACTATTTAATGAGTCGTGGTATTTCTCAAAGAGAAGCG
GAACGTCTTGTTATACATGGTTTCTTAGATCCAGTAGTACGTGAATTACCTATCGAAGAC
GTTAAACGTCAATTGAGAGAAGTAATTGAACGCAAAGTTTCTAAATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: NWMN_0786 [new locus tag: NWMN_RS04445 ]
- symbol: SufD
- description: FeS assembly protein SufD
- length: 435
- theoretical pI: 5.20929
- theoretical MW: 48548.3
- GRAVY: -0.353103
⊟Function[edit | edit source]
- TIGRFAM: Biosynthesis of cofactors, prosthetic groups, and carriers Other FeS assembly protein SufD (TIGR01981; HMM-score: 239.2)Biosynthesis of cofactors, prosthetic groups, and carriers Other FeS assembly protein SufB (TIGR01980; HMM-score: 232.9)
- TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
- PFAM: no clan defined UPF0051; Uncharacterized protein family (UPF0051) (PF01458; HMM-score: 195.1)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- LocateP: Intracellular
- Prediction by SwissProt Classification: Cytoplasmic
- Pathway Prediction: No pathway
- Intracellular possibility: 1
- Signal peptide possibility: -1
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.003227
- TAT(Tat/SPI): 0.000212
- LIPO(Sec/SPII): 0.000472
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQVDDNASKDGVIVEGLADALMNHSDLVQKYFMKDAVTVDEHRITALHTALVNGGVFVYVPKNVVVEHPVQYVVLHDDENASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIISEVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNLFGDRSTSSLKSVVVGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYIKHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMSRGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulators: PerR* (repression) regulon, SigB (activation) regulon
PerR* (TF) important in Oxidative stress response; RegPrecise transcription unit transferred from N315 data RegPrecise SigB (sigma factor) controlling a large regulon involved in stress/starvation response and adaptation; [1] other strains
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Bettina Schulthess, Dominik A Bloes, Patrice François, Myriam Girard, Jacques Schrenzel, Markus Bischoff, Brigitte Berger-Bächi
The σB-dependent yabJ-spoVG operon is involved in the regulation of extracellular nuclease, lipase, and protease expression in Staphylococcus aureus.
J Bacteriol: 2011, 193(18);4954-62
[PubMed:21725011] [WorldCat.org] [DOI] (I p)