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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_001454
  • pan locus tag?: SAUPAN003930000
  • symbol: JSNZ_001454
  • pan gene symbol?: hepT
  • synonym:
  • product: polyprenyl synthetase family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_001454
  • symbol: JSNZ_001454
  • product: polyprenyl synthetase family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1500961..1501920
  • length: 960
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    GTGGCAAAGTTAAACATGAACAATGAAATTAAGAAAGTGGAACAACGACTTGAAAAGGCA
    ATAAAAAGTAAAGATTCTGTATTAGAACAGGCATCATTACACTTATTGTCTTCTGGTGGT
    AAAAGAGTACGCCCAGCATTTGTTATTCTGAGTAGCCAATTTGGCAAAGATGAACAAACG
    TCTGAACAAACGTATCAAGTTGCAGTCGCATTAGAGTTAATTCATATGGCAACACTTGTT
    CATGATGACGTTATTGATAAAAGCGACAAGCGTCGAGGCAAGTTAACCATATCAAAGAAA
    TGGGATCAGACAACTGCTATTTTAACTGGGAATTTTTTATTGGCATTAGGACTTGAACAC
    TTAATGGCAGTTAAAGATAATCGTGTACATCAATTAATATCTGAATCTATCGTTGATGTT
    TGTAGAGGGGAACTTTTCCAATTTCAAGACCAATTTAACAGTCAACAGACAATTATCAAT
    TATTTACGACGTATCAATCGCAAAACAGCACTGTTAATTCAATTATCAACTGAAGTTGGT
    GCAATTACATCTCAATCTGATAAAGAGACTGTACGAAAATTGAAAATGATTGGTCATTAT
    ATAGGTATGAGCTTCCAAATCATTGATGATGTATTAGACTTCACAAGTACCGAAAAGAAA
    TTAGGTAAGCCGGTCGGAAGTGATTTGCTTAATGGTCATATTACGTTACCGATTTTATTA
    GAAATGCGTAAAAACCCAGACTTCAAATTGAAAATTGAACAATTACGTCGTGATAGTGAA
    CGTAAAGAATTTGAAGAATGTATCCAAATCATTAGAAAATCTGACAGCATCGATGAGGCT
    AAGGCAGTAAGTTCGAAGTATTTAAGTAAAGCTTTGGATTTGATTTCTGAGTTACCAGAT
    GGACATCCGAAATCACTACTTTTAAGTTTGACGAAAAAAATGGGTTCAAGAAACACGTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_001454
  • symbol: JSNZ_001454
  • description: polyprenyl synthetase family protein
  • length: 319
  • theoretical pI: 9.78585
  • theoretical MW: 36143.6
  • GRAVY: -0.353605

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone heptaprenyl diphosphate synthase component II (TIGR02748; EC 2.5.1.30; HMM-score: 377.7)
    and 1 more
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone solanesyl diphosphate synthase (TIGR02749; EC 2.5.1.-; HMM-score: 242.3)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    Terp_synthase (CL0613) polyprenyl_synt; Polyprenyl synthetase (PF00348; HMM-score: 239.4)
    and 4 more
    HEPPP_synt_1; Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 (PF07307; HMM-score: 28.1)
    bHLH (CL0827) bHLH_INO2; INO2 bHLH domain (PF23179; HMM-score: 17.9)
    no clan defined Baculo_p33; Baculovirus P33 (PF05214; HMM-score: 16.5)
    NADP_Rossmann (CL0063) Pyr_redox_3; Pyridine nucleotide-disulphide oxidoreductase (PF13738; HMM-score: 15.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.8706
    • Cytoplasmic Membrane Score: 0.1193
    • Cell wall & surface Score: 0.0013
    • Extracellular Score: 0.0089
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006431
    • TAT(Tat/SPI): 0.001573
    • LIPO(Sec/SPII): 0.000712
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MAKLNMNNEIKKVEQRLEKAIKSKDSVLEQASLHLLSSGGKRVRPAFVILSSQFGKDEQTSEQTYQVAVALELIHMATLVHDDVIDKSDKRRGKLTISKKWDQTTAILTGNFLLALGLEHLMAVKDNRVHQLISESIVDVCRGELFQFQDQFNSQQTIINYLRRINRKTALLIQLSTEVGAITSQSDKETVRKLKMIGHYIGMSFQIIDDVLDFTSTEKKLGKPVGSDLLNGHITLPILLEMRKNPDFKLKIEQLRRDSERKEFEECIQIIRKSDSIDEAKAVSSKYLSKALDLISELPDGHPKSLLLSLTKKMGSRNT

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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