PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

FunGene: 08-OCT-2024

⊟Summary

• organism: Staphylococcus aureus JSNZ
• locus tag: JSNZ_001204
• pan locus tag^?: SAUPAN003522000
• symbol: ftsY
• pan gene symbol^?: ftsY
• synonym:
• product: signal recognition particle-docking protein FtsY

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: JSNZ_001204
• symbol: ftsY
• product: signal recognition particle-docking protein FtsY
• replicon: chromosome
• strand: +
• coordinates: 1210562..1211812
• length: 1251
• essential: unknown other strains

⊟Accession numbers

• Gene ID:
• RefSeq:
• BioCyc:
• MicrobesOnline:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  961
  1021
  1081
  1141
  1201
  
  ATGAGCTTTTTTAAACGCTTAAAAGATAAGTTTGCAACAAATAAAGAAAATGAAGAAGTT
  AAATCCTTAACAGAAGAACAAGGCCAAGACAAATTAGAAGATACACATTCTGAAGGTTCA
  ACGCAGGACGTAAATGATTTAGCAGGAAATGCTGAAGTGAAAAAGAAGCCACGCAAGTTG
  AGTGAAGCGGATTTTGATGACGATGGCTTAATATCAATTGAAGATTTTGAAGAAATTGAA
  GCTCAAAAAATGGGTGCTAAATTTAAAGCAGGACTCGAAAAATCTCGTCAAAATTTCCAA
  GAACAATTAAATAATTTGATAGCGAGATATCGTAAAGTAGATGAAGACTTTTTTGAAGCT
  TTAGAAGAAATGTTAATCACTGCAGACGTCGGTTTTAATACAGTGATGACGTTAACTGAA
  GAATTACGTATGGAAGCACAACGACGTAATATTCAAGATACTGAAGATTTGCGTGAAGTC
  ATTGTTGAAAAAATCGTAGAGATTTACCATCAAGAAGATGATAATTCAGAAGCTATGAAC
  TTAGAAGATGGTCGTTTAAATGTCATTTTAATGGTTGGTGTGAATGGTGTTGGTAAAACA
  ACAACAATTGGAAAATTAGCTTACCGATATAAAATGGAAGGTAAAAAAGTAATGTTAGCT
  GCGGGCGATACTTTTAGAGCGGGTGCTATTGATCAATTGAAAGTTTGGGGCGAACGTGTT
  GGTGTAGATGTAATTAGCCAAAGTGAAGGTTCTGATCCAGCTGCTGTTATGTATGATGCG
  ATTAATGCCGCTAAAAACAAAGGTGTTGATATTTTAATCTGTGATACCGCTGGACGTTTA
  CAAAATAAAACAAATCTAATGCAAGAATTAGAAAAAGTTAAGCGTGTAATTAATCGAGCA
  GTGCCAGATGCGCCTCATGAAGCATTACTATGTTTAGATGCTACAACTGGTCAGAATGCG
  TTGTCACAAGCTAGAAACTTTAAAGAAGTAACAAATGTTACAGGTATTGTATTAACGAAA
  TTAGATGGTACAGCCAAAGGTGGTATCGTATTAGCCATTCGTAATGAATTGCACATTCCA
  GTTAAATATGTAGGTTTAGGTGAGCAATTAGATGACTTACAACCATTTAACCCTGAAAGT
  TATGTCTACGGCTTATTCGCTGATATGATTGAACAAAATGAAGAAATAACAACAGTTGAA
  AATGATCAAATTGTAACAGAAGTAAAGGACGATAATCATGGGGCAAAATGA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  780
  840
  900
  960
  1020
  1080
  1140
  1200
  1251
  

⊟Protein

⊟General

• locus tag: JSNZ_001204
• symbol: FtsY
• description: signal recognition particle-docking protein FtsY
• length: 416
• theoretical pI: 4.426
• theoretical MW: 46500
• GRAVY: -0.507692

⊟Function

• TIGRFAM:
  Genetic information processing Protein fate Protein and peptide secretion and trafficking signal recognition particle-docking protein FtsY (TIGR00064; HMM-score: 389.3)
  and 11 more
  Genetic information processing Protein fate Protein and peptide secretion and trafficking signal recognition particle protein (TIGR00959; HMM-score: 233.6)
  signal recognition particle protein SRP54 (TIGR01425; HMM-score: 185.8)
  Cellular processes Cellular processes Chemotaxis and motility flagellar biosynthesis protein FlhF (TIGR03499; HMM-score: 90.4)
  Unknown function General small GTP-binding protein domain (TIGR00231; HMM-score: 18.1)
  Metabolism Transport and binding proteins Amino acids, peptides and amines LAO/AO transport system ATPase (TIGR00750; EC 2.7.-.-; HMM-score: 16.8)
  Signal transduction Regulatory functions Protein interactions LAO/AO transport system ATPase (TIGR00750; EC 2.7.-.-; HMM-score: 16.8)
  arsenical pump-driving ATPase (TIGR04291; EC 3.6.1.-; HMM-score: 15.9)
  Genetic information processing Protein fate Protein modification and repair hydrogenase accessory protein HypB (TIGR00073; HMM-score: 15.7)
  Metabolism Transport and binding proteins Cations and iron carrying compounds cobalt ABC transporter, ATP-binding protein (TIGR01166; HMM-score: 13.2)
  Unknown function General putative selenium-dependent hydroxylase accessory protein YqeC (TIGR03172; HMM-score: 12.8)
  thiol reductant ABC exporter, CydD subunit (TIGR02857; HMM-score: 12)
• TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
• PFAM:
  P-loop_NTPase (CL0023) SRP54; SRP54-type protein, GTPase domain (PF00448; HMM-score: 272.1)
  and 20 more
  no clan defined SRP54_N; SRP54-type protein, helical bundle domain (PF02881; HMM-score: 51)
  P-loop_NTPase (CL0023) AAA_30; AAA domain (PF13604; HMM-score: 19)
  nSTAND3; Novel STAND NTPase 3 (PF20720; HMM-score: 18.7)
  AAA_22; AAA domain (PF13401; HMM-score: 18.4)
  MeaB; Methylmalonyl Co-A mutase-associated GTPase MeaB (PF03308; HMM-score: 18.3)
  ABC_tran; ABC transporter (PF00005; HMM-score: 17.7)
  AAA_17; AAA domain (PF13207; HMM-score: 16.4)
  AAA_16; AAA ATPase domain (PF13191; HMM-score: 16.1)
  AAA_31; AAA domain (PF13614; HMM-score: 15.7)
  AAA_33; AAA domain (PF13671; HMM-score: 15.1)
  Zeta_toxin; Zeta toxin (PF06414; HMM-score: 14.3)
  CbiA; CobQ/CobB/MinD/ParA nucleotide binding domain (PF01656; HMM-score: 14)
  RsgA_GTPase; RsgA GTPase (PF03193; HMM-score: 13.7)
  no clan defined Scm3; Centromere protein Scm3 (PF10384; HMM-score: 13.2)
  P-loop_NTPase (CL0023) APS_kinase; Adenylylsulphate kinase (PF01583; HMM-score: 13.1)
  AAA_24; AAA domain (PF13479; HMM-score: 13)
  YqeC; YqeC protein (PF19842; HMM-score: 12.9)
  Thymidylate_kin; Thymidylate kinase (PF02223; HMM-score: 11.5)
  MMR_HSR1; 50S ribosome-binding GTPase (PF01926; HMM-score: 11.1)
  AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 10.3)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 1.05
  • Cytoplasmic Membrane Score: 8.78
  • Cellwall Score: 0.08
  • Extracellular Score: 0.09
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.6948
  • Cytoplasmic Membrane Score: 0.267
  • Cell wall & surface Score: 0.0005
  • Extracellular Score: 0.0378
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.008211
  • TAT(Tat/SPI): 0.002047
  • LIPO(Sec/SPII): 0.002734
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq:
• UniProt:

⊟Protein sequence

• MSFFKRLKDKFATNKENEEVKSLTEEQGQDKLEDTHSEGSTQDVNDLAGNAEVKKKPRKLSEADFDDDGLISIEDFEEIEAQKMGAKFKAGLEKSRQNFQEQLNNLIARYRKVDEDFFEALEEMLITADVGFNTVMTLTEELRMEAQRRNIQDTEDLREVIVEKIVEIYHQEDDNSEAMNLEDGRLNVILMVGVNGVGKTTTIGKLAYRYKMEGKKVMLAAGDTFRAGAIDQLKVWGERVGVDVISQSEGSDPAAVMYDAINAAKNKGVDILICDTAGRLQNKTNLMQELEKVKRVINRAVPDAPHEALLCLDATTGQNALSQARNFKEVTNVTGIVLTKLDGTAKGGIVLAIRNELHIPVKYVGLGEQLDDLQPFNPESYVYGLFADMIEQNEEITTVENDQIVTEVKDDNHGAK

⊟Experimental data

• experimentally validated: data available for COL, NCTC8325
• protein localization: data available for COL
• quantitative data / protein copy number per cell: data available for COL
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications