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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS11030 [old locus tag: SACOL2108 ]
  • pan locus tag?: SAUPAN005407000
  • symbol: SACOL_RS11030
  • pan gene symbol?: —
  • synonym:
  • product: threonylcarbamoyl-AMP synthase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS11030 [old locus tag: SACOL2108 ]
  • symbol: SACOL_RS11030
  • product: threonylcarbamoyl-AMP synthase
  • replicon: chromosome
  • strand: -
  • coordinates: 2167902..2168999
  • length: 1098
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002951 (2167902..2168999) NCBI
  • BioCyc: SACOL_RS11030 BioCyc
  • MicrobesOnline: see SACOL2108

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    GTGCATAGCTTTTTGCTTTATATTATGATAAATAAGAAAGGCGTGATTAAGTTGGATACT
    AAAATTTGGGATGTTAGAGAATATAATGAAGATTTACAGCAATATCCTAAAATTAATGAA
    ATAAAAGACATTGTTTTAAACGGTGGTTTAATAGGTTTACCAACTGAAACAGTTTATGGA
    CTTGCAGCAAATGCGACAGATGAAGAAGCTGTAGCTAAAATATATGAAGCTAAAGGCCGT
    CCATCTGACAATCCGCTTATTGTTCATATACACAGTAAAGGTCAATTAAAAGATTTTACA
    TATACTTTGGATCCACGCGTAGAAAAGTTAATGCAGGCATTCTGGCCGGGCCCTATTTCG
    TTTATATTGCCGTTAAAGCTAGGCTATCTATGTCGAAAAGTTTCTGGAGGTTTATCATCA
    GTTGCTGTTAGAATGCCAAGCCATTCTGTAGGTAGACAATTATTACAAATCATAAATGAA
    CCTCTAGCTGCTCCAAGTGCTAATTTAAGTGGTAGACCTTCACCAACAACTTTCAATCAT
    GTATATCAAGATTTGAATGGCCGTATCGATGGTATTGTTCAAGCTGAACAAAGTGAAGAA
    GGATTAGAAAGTACGGTTTTAGATTGCACATCTTTTCCTTATAAAATTGCAAGACCTGGT
    TCTATAACAGCAGCAATGATTACAGAAATACTTCCGAATAGTATCGCCCATGCTGATTAT
    AATGATACTGAACAGCCAATTGCACCAGGTATGAAGTATAAGCATTACTCACCCAATACA
    CCACTTACAATTATTACAGATATTGAGAGCAAAATTGGAAATGACGGTAAAGATTGGTCT
    TCTATAGCTTTTATTGTGCCGAGTAATAAGGTGGCGTTTATACCAAGTGAAGCGCAATTC
    ATTCAATTATGTCAGGATGACAATGATGTTAAACAAGCAAGTCATAATCTTTATGATGTG
    TTACATTCACTTGATGAAAATGAAAATATTTCAGCGGCGTATATATACGGCTTTGAGCTG
    AATGATAATACAGAAGCAATTATGAATCGCATGTTAAAAGCTGCAGGTAATCACATTATT
    AAAGGATGTGAACTATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1098

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL_RS11030 [old locus tag: SACOL2108 ]
  • symbol: SACOL_RS11030
  • description: threonylcarbamoyl-AMP synthase
  • length: 365
  • theoretical pI: 5.23175
  • theoretical MW: 40444.8
  • GRAVY: -0.22137

⊟Function[edit | edit source]

  • ⊞reaction:
    EC 2.7.7.87?  ExPASy
    L-threonylcarbamoyladenylate synthase L-threonine + ATP + HCO3(-) = L-threonylcarbamoyladenylate + diphosphate + H2O
  • ⊞TIGRFAM:
    Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family (TIGR00057; HMM-score: 194.3)
    and 1 more
    Genetic information processing Protein fate Protein modification and repair carbamoyltransferase HypF (TIGR00143; HMM-score: 27.2)
  • TheSEED: see SACOL2108
  • ⊞PFAM:
    no clan defined Sua5_yciO_yrdC; Telomere recombination (PF01300; HMM-score: 193.2)
    and 1 more
    GT-B (CL0113) Sua5_C; Threonylcarbamoyl-AMP synthase, C-terminal domain (PF03481; HMM-score: 90.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9833
    • Cytoplasmic Membrane Score: 0.0028
    • Cell wall & surface Score: 0.0003
    • Extracellular Score: 0.0136
  • LocateP:
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004616
    • TAT(Tat/SPI): 0.000177
    • LIPO(Sec/SPII): 0.000577
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MHSFLLYIMINKKGVIKLDTKIWDVREYNEDLQQYPKINEIKDIVLNGGLIGLPTETVYGLAANATDEEAVAKIYEAKGRPSDNPLIVHIHSKGQLKDFTYTLDPRVEKLMQAFWPGPISFILPLKLGYLCRKVSGGLSSVAVRMPSHSVGRQLLQIINEPLAAPSANLSGRPSPTTFNHVYQDLNGRIDGIVQAEQSEEGLESTVLDCTSFPYKIARPGSITAAMITEILPNSIAHADYNDTEQPIAPGMKYKHYSPNTPLTIITDIESKIGNDGKDWSSIAFIVPSNKVAFIPSEAQFIQLCQDDNDVKQASHNLYDVLHSLDENENISAAYIYGFELNDNTEAIMNRMLKAAGNHIIKGCEL

⊟Experimental data[edit | edit source]

  • experimentally validated: see SACOL2108
  • protein localization: see SACOL2108
  • quantitative data / protein copy number per cell: see SACOL2108
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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