PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA_RS07400 [old locus tag: SA1308 ]
• pan locus tag^?: SAUPAN003937000
• symbol: SA_RS07400
• pan gene symbol^?: rpsA
• synonym:
• product: 30S ribosomal protein S1

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA_RS07400 [old locus tag: SA1308 ]
• symbol: SA_RS07400
• product: 30S ribosomal protein S1
• replicon: chromosome
• strand: -
• coordinates: 1513700..1514875
• length: 1176
• essential: no DEG other strains

⊟Accession numbers

• Location: NC_002745 (1513700..1514875) NCBI
• BioCyc: SA_RS07400 BioCyc
• MicrobesOnline: see SA1308

⊟Phenotype

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⊟DNA sequence

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  ATGACTGAAGAATTCAATGAATCAATGATTAACGATATTAAAGAAGGTGACAAAGTCACT
  GGCGAGGTACAACAAGTTGAAGACAAGCAAGTTGTTGTTCATATCAACGGTGGTAAATTT
  AATGGGATTATTCCTATTAGTCAACTATCTACGCATCATATTGATAGCCCAAGTGAAGTT
  GTAAAAGAGGGCGACGAAGTTGAAGCATATGTCACTAAAGTTGAGTTTGATGAAGAAAAT
  GAAACTGGAGCTTACATCTTATCTAGAAGACAACTTGAAACTGAGAAGTCTTATAGTTAT
  TTACAAGAAAAATTAGATAATAATGAAATCATCGAAGCGAAAGTAACAGAAGTAGTTAAA
  GGTGGTTTGGTTGTTGATGTAGGACAAAGAGGTTTTGTTCCGGCTTCACTAATTTCAACA
  GACTTCATTGAGGATTTCTCTGTGTTTGATGGACAAACAATTCGTATTAAAGTTGAAGAA
  TTGGATCCTGAAAATAATAGAGTCATTTTAAGCCGTAAAGCAGTTGAACAAGAAGAAAAC
  GATGCTAAAAAAGATCAATTATTACAATCTTTAAATGAAGGCGATGTTATTCATGGTAAA
  GTAGCGCGTTTAACTCAATTTGGTGCATTTATAGACATTGGTGGTGTTGATGGTTTAGTG
  CATGTATCTGAACTTTCTCACGAACATGTTCAAACACCAGAAGAAGTAGTTTCAATTGGT
  CAAGATGTTAAAGTTAAAATTAAATCTATTGATAGAGATACAGAACGTATTTCATTATCA
  ATCAAAGATACGTTACCAACACCTTTCGAAAATATTAAAGGTCAATTCCACGAAAATGAT
  GTCATTGAAGGTGTCGTAGTAAGATTGGCAAACTTTGGTGCATTTGTTGAAATTGCACCA
  GGTGTACAAGGACTTGTACATATTTCTGAAATTGCACACAAACACATTGGTACGCCAGGT
  GAAGTGTTAGAACCTGGTCAACAAGTAAATGTTAAAATATTAGGTATTGATGAAGAGAAT
  GAAAGAGTATCACTATCTATTAAAGCAACATTACCAAACGAAGATGTTGTTGAAAGTGAT
  CCTTCTACGACTAAGGCGTACTTAGAAAACGAAGAAGAAGATAATCCAACAATTGGCGAT
  ATGATTGGTGATAAACTTAAAAATCTTAAACTATAA
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⊟Protein

⊟General

• locus tag: SA_RS07400 [old locus tag: SA1308 ]
• symbol: SA_RS07400
• description: 30S ribosomal protein S1
• length: 391
• theoretical pI: 4.27604
• theoretical MW: 43309
• GRAVY: -0.38977

⊟Function

• TIGRFAM:
  Genetic information processing Protein synthesis Ribosomal proteins: synthesis and modification ribosomal protein bS1 (TIGR00717; HMM-score: 286.7)
  and 8 more
  Genetic information processing Transcription Degradation of RNA polyribonucleotide nucleotidyltransferase (TIGR03591; EC 2.7.7.8; HMM-score: 147.6)
  guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase (TIGR02696; EC 2.7.-.-,2.7.7.8; HMM-score: 59.4)
  Genetic information processing Transcription DNA-dependent RNA polymerase DNA-directed RNA polymerase (TIGR00448; EC 2.7.7.6; HMM-score: 44)
  Genetic information processing Transcription Degradation of RNA ribonuclease R (TIGR02063; EC 3.1.-.-; HMM-score: 37)
  MAST domain (TIGR04204; HMM-score: 14.1)
  Metabolism Energy metabolism Glycolysis/gluconeogenesis carbon storage regulator (TIGR00202; HMM-score: 9.8)
  Signal transduction Regulatory functions RNA interactions carbon storage regulator (TIGR00202; HMM-score: 9.8)
  Genetic information processing Protein fate Protein and peptide secretion and trafficking preprotein translocase, YajC subunit (TIGR00739; HMM-score: 9.6)
• TheSEED: see SA1308
• PFAM:
  OB (CL0021) S1; S1 RNA binding domain (PF00575; HMM-score: 251)
  and 8 more
  CusF_Ec; Copper binding periplasmic protein CusF (PF11604; HMM-score: 17.1)
  Cdc48_2-like (CL0402) CDC48_2; Cell division protein 48 (CDC48), domain 2 (PF02933; HMM-score: 16)
  OB (CL0021) S1_2; S1 domain (PF13509; HMM-score: 15.6)
  EXOSC1; Exosome component EXOSC1/CSL4 (PF10447; HMM-score: 13.4)
  RuvA_N; RuvA N terminal domain (PF01330; HMM-score: 11.5)
  no clan defined DUF1967; Domain of unknown function (DUF1967) (PF09269; HMM-score: 9.9)
  CsrA; Global regulator protein family (PF02599; HMM-score: 7.9)
  KOW (CL0107) KOW; KOW motif (PF00467; HMM-score: 7)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 9.97
  • Cytoplasmic Membrane Score: 0
  • Cellwall Score: 0.01
  • Extracellular Score: 0.02
  • Internal Helices: 0
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.021822
  • TAT(Tat/SPI): 0.000535
  • LIPO(Sec/SPII): 0.000886
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 446056106 NCBI
• RefSeq: WP_000133961 NCBI
• UniProt: see SA1308

⊟Protein sequence

• MTEEFNESMINDIKEGDKVTGEVQQVEDKQVVVHINGGKFNGIIPISQLSTHHIDSPSEVVKEGDEVEAYVTKVEFDEENETGAYILSRRQLETEKSYSYLQEKLDNNEIIEAKVTEVVKGGLVVDVGQRGFVPASLISTDFIEDFSVFDGQTIRIKVEELDPENNRVILSRKAVEQEENDAKKDQLLQSLNEGDVIHGKVARLTQFGAFIDIGGVDGLVHVSELSHEHVQTPEEVVSIGQDVKVKIKSIDRDTERISLSIKDTLPTPFENIKGQFHENDVIEGVVVRLANFGAFVEIAPGVQGLVHISEIAHKHIGTPGEVLEPGQQVNVKILGIDEENERVSLSIKATLPNEDVVESDPSTTKAYLENEEEDNPTIGDMIGDKLKNLKL

⊟Experimental data

• experimentally validated: data available for COL, NCTC8325
• protein localization: data available for COL
• quantitative data / protein copy number per cell: data available for COL
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: data available for COL

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications