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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 03-AUG-2016

Summary[edit | edit source]

  • organism: Staphylococcus aureus NCTC8325
  • locus tag: SAOUHSC_02224
  • pan locus tag?: SAUPAN005109000
  • symbol: SAOUHSC_02224
  • pan gene symbol?:
  • synonym:
  • product: phi PVL orf 38-like protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAOUHSC_02224
  • symbol: SAOUHSC_02224
  • product: phi PVL orf 38-like protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2067887..2068048
  • length: 162
  • essential: no DEG other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    ATGAGCAACATTTATAAAAGCTACCTAGTAGCAGTACTGTGCTTTACAGTCTTAGCAATT
    GTACTTATGCCGTTTCTATACTTCACTACTGCATGGTCGATTGCGGGATTCGCAAGTATC
    GCAACATTCATATTTTATAAGGAATACTTTTATGAAGAATAA
    60
    120
    162

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SAOUHSC_02224
  • symbol: SAOUHSC_02224
  • description: phi PVL orf 38-like protein
  • length: 53
  • theoretical pI: 4.47936
  • theoretical MW: 6198.3
  • GRAVY: 1.06604

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • Phage phi 11 orf10a protein homolog
  • PFAM:
    no clan defined DUF1270; Protein of unknown function (DUF1270) (PF06900; HMM-score: 131.8)
    and 2 more
    EcsB; Bacterial ABC transporter protein EcsB (PF05975; HMM-score: 14.1)
    DUF2244; Integral membrane protein (DUF2244) (PF10003; HMM-score: 11.4)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.32
    • Cytoplasmic Membrane Score: 9.55
    • Cellwall Score: 0.12
    • Extracellular Score: 0.01
    • Internal Helix: 1
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: 0.5
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.038527
    • TAT(Tat/SPI): 0.007372
    • LIPO(Sec/SPII): 0.053786
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MSNIYKSYLVAVLCFTVLAIVLMPFLYFTTAWSIAGFASIATFIFYKEYFYEE

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

  1. 1.0 1.1 Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
    Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
    PLoS Genet: 2016, 12(4);e1005962
    [PubMed:27035918] [WorldCat.org] [DOI] (I e)

Relevant publications[edit | edit source]