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NCBI: 10-JUN-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus COL
- locus tag: SACOL1269 [new locus tag: SACOL_RS06480 ]
- pan locus tag?: SAUPAN003550000
- symbol: xerC
- pan gene symbol?: xerC
- synonym:
- product: tyrosine recombinase XerC
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SACOL1269 [new locus tag: SACOL_RS06480 ]
- symbol: xerC
- product: tyrosine recombinase XerC
- replicon: chromosome
- strand: +
- coordinates: 1280539..1281435
- length: 897
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 3238030 NCBI
- RefSeq: YP_186127 NCBI
- BioCyc: see SACOL_RS06480
- MicrobesOnline: 912733 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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841TTGAATCATATTCAAGATGCGTTTTTAAATACATTGAAAGTTGAACGGAATTTTTCGGAA
CACACATTGAAATCATATCAAGATGACTTAATTCAGTTTAATCAATTTTTAGAACAAGAA
CATTTAGAGTTGAATACTTTTGAATACAGAGATGCTAGAAATTATTTGAGCTATTTATAT
TCAAATCATTTGAAAAGAACATCTGTTTCTCGTAAAATCTCAACGTTAAGAACTTTCTAT
GAATATTGGATGACGCTTGATGAGAACATTATTAATCCATTTGTTCAATTAGTACATCCG
AAAAAAGAAAAATATCTTCCGCAATTCTTTTACGAAGAAGAAATGGAAGCGTTATTCAAA
ACTGTAGAAGAGGACACTTCAAAAAATTTACGGGATCGAGTTATTCTTGAATTGTTGTAT
GCTACAGGCATCCGTGTTTCGGAATTAGTAAATATTAAAAAACAAGATATAGATTTTTAC
GCGAATGGTGTTACCGTATTAGGAAAAGGGAGCAAAGAGCGCTTTGTACCGTTTGGTGCT
TATTGTAGACAAAGCATCGAAAATTATTTAGAACATTTCAAACCAATTCAGTCATGCAAT
CATGATTTTCTTATTGTAAATATGAAGGGTGAAGCAATCACTGAACGCGGTGTACGATAT
GTTTTAAATGATATTGTTAAACGAACAGCAGGCGTAAGTGAGATTCATCCCCACAAGCTC
AGACATACATTTGCAACGCATTTATTGAATCAAGGTGCAGACCTAAGAACAGTACAATCG
TTATTAGGTCATGTTAATTTGTCAACAACTGGTAAATATACACACGTATCTAACCAACAA
TTAAGAAAAGTGTATCTAAATGCACATCCTCGAGCGAAAAAGGAGAATGAAACATGA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SACOL1269 [new locus tag: SACOL_RS06480 ]
- symbol: XerC
- description: tyrosine recombinase XerC
- length: 298
- theoretical pI: 8.5616
- theoretical MW: 35112.6
- GRAVY: -0.563423
⊟Function[edit | edit source]
- TIGRFAM: DNA metabolism DNA replication, recombination, and repair tyrosine recombinase XerC (TIGR02224; HMM-score: 352.2)DNA metabolism DNA replication, recombination, and repair tyrosine recombinase XerD (TIGR02225; HMM-score: 298.8)and 2 moreDNA metabolism DNA replication, recombination, and repair integron integrase (TIGR02249; HMM-score: 120.5)Mobile and extrachromosomal element functions Other integron integrase (TIGR02249; HMM-score: 120.5)
- TheSEED :
- Site-specific tyrosine recombinase
- PFAM: DNA-mend (CL0382) Phage_integrase; Phage integrase family (PF00589; HMM-score: 154.7)and 5 morel-integrase_N (CL0469) Phage_int_SAM_1; Phage integrase, N-terminal SAM-like domain (PF02899; HMM-score: 63)Phage_int_SAM_4; Phage integrase, N-terminal SAM-like domain (PF13495; HMM-score: 34.5)Phage_int_SAM_5; Phage integrase SAM-like domain (PF13102; HMM-score: 21.7)DNA-mend (CL0382) Integrase_1; Integrase (PF12835; HMM-score: 18.6)Phage_integr_3; Archaeal phage integrase (PF16795; HMM-score: 15.4)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- LocateP: Intracellular
- Prediction by SwissProt Classification: Cytoplasmic
- Pathway Prediction: No pathway
- Intracellular possibility: 1
- Signal peptide possibility: -1
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.001925
- TAT(Tat/SPI): 0.000636
- LIPO(Sec/SPII): 0.000337
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MNHIQDAFLNTLKVERNFSEHTLKSYQDDLIQFNQFLEQEHLELNTFEYRDARNYLSYLYSNHLKRTSVSRKISTLRTFYEYWMTLDENIINPFVQLVHPKKEKYLPQFFYEEEMEALFKTVEEDTSKNLRDRVILELLYATGIRVSELVNIKKQDIDFYANGVTVLGKGSKERFVPFGAYCRQSIENYLEHFKPIQSCNHDFLIVNMKGEAITERGVRYVLNDIVKRTAGVSEIHPHKLRHTFATHLLNQGADLRTVQSLLGHVNLSTTGKYTHVSNQQLRKVYLNAHPRAKKENET
⊟Experimental data[edit | edit source]
- experimentally validated: PeptideAtlas
- protein localization: Cytoplasmic [1] [2]
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: xerC > hslV > hslU > codY
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Dörte Becher, Kristina Hempel, Susanne Sievers, Daniela Zühlke, Jan Pané-Farré, Andreas Otto, Stephan Fuchs, Dirk Albrecht, Jörg Bernhardt, Susanne Engelmann, Uwe Völker, Jan Maarten van Dijl, Michael Hecker
A proteomic view of an important human pathogen--towards the quantification of the entire Staphylococcus aureus proteome.
PLoS One: 2009, 4(12);e8176
[PubMed:19997597] [WorldCat.org] [DOI] (I e) - ↑ Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
The Staphylococcus aureus proteome.
Int J Med Microbiol: 2014, 304(2);110-20
[PubMed:24439828] [WorldCat.org] [DOI] (I p)