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FunGene: 08-OCT-2024

Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_002270
  • pan locus tag?: SAUPAN005772000
  • symbol: JSNZ_002270
  • pan gene symbol?:
  • synonym:
  • product: CHAP domain-containing protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_002270
  • symbol: JSNZ_002270
  • product: CHAP domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 2266444..2266953
  • length: 510
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGAAAAAATTAGTAACAGCAACTACGTTAACAGCAGGAATCGGTACAGCATTAGTAGGT
    CAAGCACATCATGCAGATGCTGCTGAAAATTATACAAATTACAACAACTATAACTACAAC
    ACGACTCAAACTAAAACGACTACAACGACTACAACAACTACGACAACTACATCATCAATT
    TCACATTCTGGTAACTTATACACTGCAGGACAATGTACTTGGTATGTATATGATAAAGTA
    GGCGGAGAAATCGGTTCTACTTGGGGAAATGCTAATAATTGGGCTGCTGCTGCACAAGGT
    GCTGGATTCACAGTAAATCATACACCTTCTAAAGGCGCTATCCTACAATCTTCTGAAGGA
    CCATTTGGTCACGTTGCATATATAGAAAGTGTAAACAGTGATGGTTCAGTTACAATTTCA
    GAAATGAATTATAGTGGCGGACCTTTCTCAGTAAGTTCTAGAACTATTTCTGCAAGTGAA
    GCAGGTAACTACAACTACATCCATATTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    510

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: JSNZ_002270
  • symbol: JSNZ_002270
  • description: CHAP domain-containing protein
  • length: 169
  • theoretical pI: 6.50327
  • theoretical MW: 17743.1
  • GRAVY: -0.374556

Function[edit | edit source]

  • TIGRFAM:
    Cell structure Cell envelope Surface structures pilus (MSHA type) biogenesis protein MshL (TIGR02519; HMM-score: 5.1)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    Peptidase_CA (CL0125) CHAP; CHAP domain (PF05257; HMM-score: 77.3)
    and 3 more
    no clan defined DUF4834; Domain of unknown function (DUF4834) (PF16118; HMM-score: 14.1)
    FG_rpt (CL0647) Nucleoporin_FG2; Nucleoporin FG repeated region (PF15967; HMM-score: 9)
    no clan defined Dicty_REP; Dictyostelium (Slime Mold) REP protein (PF05086; HMM-score: 5.9)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.02
    • Extracellular Score: 9.98
    • Internal Helices: 0
  • DeepLocPro: Extracellular
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cell wall & surface Score: 0.001
    • Extracellular Score: 0.999
  • LocateP:
  • SignalP: Signal peptide SP(Sec/SPI) length 27 aa
    • SP(Sec/SPI): 0.995543
    • TAT(Tat/SPI): 0.001657
    • LIPO(Sec/SPII): 0.002213
    • Cleavage Site: CS pos: 27-28. ADA-AE. Pr: 0.9715
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

Protein sequence[edit | edit source]

  • MKKLVTATTLTAGIGTALVGQAHHADAAENYTNYNNYNYNTTQTKTTTTTTTTTTTTSSISHSGNLYTAGQCTWYVYDKVGGEIGSTWGNANNWAAAAQGAGFTVNHTPSKGAILQSSEGPFGHVAYIESVNSDGSVTISEMNYSGGPFSVSSRTISASEAGNYNYIHI

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]