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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

organism: Staphylococcus aureus JSNZ
locus tag: JSNZ_002246
pan locus tag^?: SAUPAN005740000
symbol: modA
pan gene symbol^?: modA
synonym:
product: molybdate ABC transporter substrate-binding protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

type: CDS
locus tag: JSNZ_002246
symbol: modA
product: molybdate ABC transporter substrate-binding protein
replicon: chromosome
strand: -
coordinates: 2243421..2244203
length: 783
essential: unknown other strains

⊟Accession numbers[edit | edit source]

Gene ID:
RefSeq:
BioCyc:
MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGAAAATGAAACGTTTTATAGCTATTGTAATGGCATTATTTTTAGTATTAGCTGGTTGC
TCTAATTCTAACGATAATAATGAAAGTAAAAAAGATGACGCAGACAATGGTAAGAAACAA
GAGATTCAAGTTGCAGCGGCAGCAAGTTTAACAGATGTAACCAAGAAATTAGCTTCAGAA
TTTAAAAAAGAGCATAAAAATGCTGATATTAAATTTAACTATGGTGGATCAGGGGCATTA
AGAAAACAAATTGAATCAGGCGCACCTGTTGACGTATTTATGTCTGCAAATACTAAAGAT
GTAGATGCATTAAAAGACAAGAATAAAGCGCATGATACATATAAATATGCGAAAAATAGT
CTAGTATTAATTGGTGATAAAGATTCAAATTACACTTCAGTAAAAGACTTAAAAGACAAT
GATAAATTAGCATTAGGTGAAGTGAAAACTGTACCAGCAGGAAAATATGCGAAACAGTAT
TTAGATAACAATAACTTATTTAAAGAAGTCGAAAGTAAAATCGTTTATGCTAAAGATGTA
AAACAAGTATTAAATTATGTTGAAAAGGGTAATGCGAAACAAGGTTTTGTGTATAAAACT
GACTTATATAAACAAAACAAAAAAATTGATACTGTAAAAGTAATTAAAGAAGTAGAACTT
AAGAAACCAATCACATACGAAGCTGGTGCTACATCAGATAGTAAATTAGCAAAAGAGTGG
ATGGAATTCTTAAAATCAGATAAAGCTAAAGAAATATTAAAAGAATACCACTTTGCAGCA
TAA
60
120
180
240
300
360
420
480
540
600
660
720
780
783

⊟Protein[edit | edit source]

⊟General[edit | edit source]

locus tag: JSNZ_002246
symbol: ModA
description: molybdate ABC transporter substrate-binding protein
length: 260
theoretical pI: 9.79443
theoretical MW: 29117.1
GRAVY: -0.647308

⊟Function[edit | edit source]

TIGRFAM:
Metabolism Transport and binding proteins Anions molybdate ABC transporter, periplasmic molybdate-binding protein (TIGR01256; HMM-score: 184.5)
and 3 more
Metabolism Transport and binding proteins Anions phosphate binding protein (TIGR02136; HMM-score: 37.2)
tungstate ABC transporter binding protein WtpA (TIGR03730; HMM-score: 34.9)
Cellular processes Cellular processes Sporulation and germination sporulation lipoprotein, YhcN/YlaJ family (TIGR02898; HMM-score: 15.5)
TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
PFAM:
PBP (CL0177) SBP_bac_11; Bacterial extracellular solute-binding protein (PF13531; HMM-score: 174.3)
and 8 more
SBP_bac_1; Bacterial extracellular solute-binding protein (PF01547; HMM-score: 73.5)
Phosphonate-bd; ABC transporter, phosphonate, periplasmic substrate-binding protein (PF12974; HMM-score: 28.1)
PBP_like_2; PBP superfamily domain (PF12849; HMM-score: 21.8)
no clan defined DUF6491; Family of unknown function (DUF6491) (PF20101; HMM-score: 16.2)
Pilus_CpaD; Pilus biogenesis CpaD protein (pilus_cpaD) (PF09476; HMM-score: 14.7)
DUF7537; Family of unknown function (DUF7537) (PF24381; HMM-score: 14)
DUF1310; Protein of unknown function (DUF1310) (PF07006; HMM-score: 10.7)
HOATZ-like; Cilia- and flagella-associated protein HOATZ-like (PF17664; HMM-score: 10.5)

⊟Structure, modifications & cofactors[edit | edit source]

domains:
modifications:
cofactors:
effectors:

⊟Localization[edit | edit source]

PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 3.33
- Cellwall Score: 3.33
- Extracellular Score: 3.33
- Internal Helices: 0
DeepLocPro: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 0.8048
- Cell wall & surface Score: 0.0098
- Extracellular Score: 0.1854
LocateP:
SignalP: Signal peptide LIPO(Sec/SPII) length 19 aa
- SP(Sec/SPI): 0.000275
- TAT(Tat/SPI): 0.000041
- LIPO(Sec/SPII): 0.999559
- Cleavage Site: CS pos: 19-20. LAG-CS. Pr: 1.0000
predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

GI:
RefSeq:
UniProt:

⊟Protein sequence[edit | edit source]

MKMKRFIAIVMALFLVLAGCSNSNDNNESKKDDADNGKKQEIQVAAAASLTDVTKKLASEFKKEHKNADIKFNYGGSGALRKQIESGAPVDVFMSANTKDVDALKDKNKAHDTYKYAKNSLVLIGDKDSNYTSVKDLKDNDKLALGEVKTVPAGKYAKQYLDNNNLFKEVESKIVYAKDVKQVLNYVEKGNAKQGFVYKTDLYKQNKKIDTVKVIKEVELKKPITYEAGATSDSKLAKEWMEFLKSDKAKEILKEYHFAA

⊟Experimental data[edit | edit source]

experimentally validated: data available for COL, NCTC8325
protein localization: data available for COL
quantitative data / protein copy number per cell:
interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

Operon-mapper ^[1] : JSNZ_002244 < modB < modA

⊟Regulation[edit | edit source]

regulator:

⊟Transcription pattern[edit | edit source]

S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

Aureolib: no data available

⊟Protein stability[edit | edit source]

half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
Bioinformatics: 2018, 34(23);4118-4120
[PubMed:29931111] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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