From AureoWiki
Revision as of 10:46, 11 March 2016 by AureoSysAdmin (talk | contribs) (Text replacement - "gene Genbank" to "gene RefSeq")
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search

NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_0135 [new locus tag: SAUSA300_RS00705 ]
  • pan locus tag?: SAUPAN000942000
  • symbol: SAUSA300_0135
  • pan gene symbol?: sodM
  • synonym:
  • product: Fe/Mn family superoxide dismutase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_0135 [new locus tag: SAUSA300_RS00705 ]
  • symbol: SAUSA300_0135
  • product: Fe/Mn family superoxide dismutase
  • replicon: chromosome
  • strand: +
  • coordinates: 154202..154801
  • length: 600
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGGCATTTAAATTACCAAATTTACCATATGCATATGATGCATTGGAACCATATATAGAT
    CAAAGAACAATGGAGTTTCATCACGACAAACATCACAATACGTACGTGACGAAATTAAAC
    GCAACAGTTGAAGGAACAGAGTTAGAGCATCAATCACTAGCGGATATGATTGCTAACTTA
    GACAAGGTACCGGAAGCGATGAGGATGTCAGTCCGTAATAATGGCGGTGGTCATTTTAAC
    CATTCATTATTCTGGGAAATACTATCACCTAATTCTGAAGAAAAAGGTGGCGTAATAGAT
    GACATCAAAGCGCAGTGGGGCACTTTAGATGAATTTAAAAATGAATTTGCAAATAAAGCA
    ACAACATTATTTGGATCAGGTTGGACTTGGTTAGTTGTTAATGATGGCAAATTAGAAATT
    GTGACAACGCCAAACCAAGATAATCCATTAACAGAAGGCAAAACACCAATCTTACTATTT
    GATGTTTGGGAGCATGCCTACTATCTGAAATATCAAAATAAACGTCCAGACTATATGACT
    GCATTTTGGAACATTGTTAACTGGAAAAAAGTTGATGAATTATACCAAGCAGCAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SAUSA300_0135 [new locus tag: SAUSA300_RS00705 ]
  • symbol: SAUSA300_0135
  • description: Fe/Mn family superoxide dismutase
  • length: 199
  • theoretical pI: 5.28358
  • theoretical MW: 23040.8
  • GRAVY: -0.583417

⊟Function[edit | edit source]

  • ⊞reaction:
    EC 1.15.1.1?  ExPASy
    Superoxide dismutase 2 superoxide + 2 H+ = O2 + H2O2
  • TIGRFAM:
  • ⊞TheSEED  :
    • Superoxide dismutase [Fe] (EC 1.15.1.1)
    • Superoxide dismutase [Mn] (EC 1.15.1.1)
    Nitrogen Metabolism Nitrogen Metabolism - no subcategory Nitric oxide synthase  Manganese superoxide dismutase (EC 1.15.1.1)
    and 5 more
    Stress Response Oxidative stress Oxidative stress  Manganese superoxide dismutase (EC 1.15.1.1)
    Stress Response Oxidative stress Oxidative stress  Superoxide dismutase [Fe] (EC 1.15.1.1)
    Stress Response Oxidative stress Oxidative stress  Superoxide dismutase [Mn] (EC 1.15.1.1)
    Stress Response Oxidative stress Protection from Reactive Oxygen Species  Manganese superoxide dismutase (EC 1.15.1.1)
    Stress Response Oxidative stress Protection from Reactive Oxygen Species  Superoxide dismutase [Fe] (EC 1.15.1.1)
  • ⊞PFAM:
    no clan defined Sod_Fe_C; Iron/manganese superoxide dismutases, C-terminal domain (PF02777; HMM-score: 141)
    and 1 more
    Sod_Fe_N; Iron/manganese superoxide dismutases, alpha-hairpin domain (PF00081; HMM-score: 111.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors: Fe2+, Mn2+
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Extracellular
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 0.09
    • Cellwall Score: 0.18
    • Extracellular Score: 9.72
    • Internal Helices: 0
  • ⊞DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9277
    • Cytoplasmic Membrane Score: 0.0004
    • Cell wall & surface Score: 0.0002
    • Extracellular Score: 0.0718
  • ⊞LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002595
    • TAT(Tat/SPI): 0.000228
    • LIPO(Sec/SPII): 0.00037
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MAFKLPNLPYAYDALEPYIDQRTMEFHHDKHHNTYVTKLNATVEGTELEHQSLADMIANLDKVPEAMRMSVRNNGGGHFNHSLFWEILSPNSEEKGGVIDDIKAQWGTLDEFKNEFANKATTLFGSGWTWLVVNDGKLEIVTTPNQDNPLTEGKTPILLFDVWEHAYYLKYQNKRPDYMTAFWNIVNWKKVDELYQAAK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • ⊞regulator: CodY (repression) regulon

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://fungenwikiserver.biologie.uni-greifswald.de/aureowiki/index.php?title=SAUSA300_0135&oldid=95872"