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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS14135 [old locus tag: SA2469 ]
  • pan locus tag?: SAUPAN006432000
  • symbol: SA_RS14135
  • pan gene symbol?: —
  • synonym:
  • product: histidinol-phosphate aminotransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS14135 [old locus tag: SA2469 ]
  • symbol: SA_RS14135
  • product: histidinol-phosphate aminotransferase
  • replicon: chromosome
  • strand: -
  • coordinates: 2780585..2781598
  • length: 1014
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (2780585..2781598) NCBI
  • BioCyc: SA_RS14135 BioCyc
  • MicrobesOnline: see SA2469

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGATTTATATTGATAAAAATGAAAGTCCAGTTACGCCGTTGGATGAAAAAACAATGACG
    TCTATTATTAGTGCAACGCCATATAATTTATATCCTGATGCAGCATATGAACAATTCAAG
    GAAGCTTATGCTAAGTTTTACGGATTATCGCCTGAACAAATTATTGCAGGAAATGGATCT
    GATGAATTGATTCAAAAGTTAATGCTGATCATGCCAGAAGGTCCGGCATTAACGCTAAAT
    CCTGATTTTTTTATGTATCAAGCATATGCGGCACAAGTAAATCGTGAAATTGCATTTGTA
    GATGCAGGATCAGATTTAACGTTTGATTTGGAAACCATTTTAACGAAAATCGATGAAGTA
    CAACCATCATTTTTTATTATGAGTAATCCACATAACCCTTCAGGCAAGCAATTTGATACG
    GCATTTTTAACAGCTATTGCAGATAAGATGAAAGCATTAAACGGATACTTTGTCATTGAT
    GAAGCATATTTAGATTATGGTACGGCATATGACGTGGAACTGGCACCACACATCTTAAGA
    ATGCGTACATTATCAAAGGCGTTTGGAATTGCCGGCTTAAGATTAGGTGTCTTAATTAGT
    ACTGCTGGAACGATAAAGCATATTCAAAAAATAGAACATCCATATCCATTAAATGTATTT
    ACGCTAAATATTGCGACTTATATTTTTAGACATAGAGAAGAGACAAGAGTATTTTTAACG
    ATGCAACGACAGTTAGCTGAGCAGTTAAAACAAATATTTGATACACATGTTGCAGATAAA
    ATGTCAGTATTCCCATCAAATGCCAATTTTGTACTTACTAAAGGTTCAGCAGCGCACCAA
    TTAGGACAATACGTATATGAACAAGGATTTAAACCTCGCTTTTATGATGAGCCGGTGATG
    AAGGGCTATGTAAGATACTCAATTGCAACAGCATCGCAGTTAAAGCAATTAGAAGAAATT
    GTTAAAGAATGGAGCGCAAAATATGATTTATCAAAAACAACGAAACACAGCTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
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    960
    1014

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS14135 [old locus tag: SA2469 ]
  • symbol: SA_RS14135
  • description: histidinol-phosphate aminotransferase
  • length: 337
  • theoretical pI: 5.87594
  • theoretical MW: 38220.5
  • GRAVY: -0.177448

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Amino acid biosynthesis Histidine family histidinol-phosphate transaminase (TIGR01141; EC 2.6.1.9; HMM-score: 196.9)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin threonine-phosphate decarboxylase (TIGR01140; EC 4.1.1.81; HMM-score: 162.1)
    and 8 more
    Cellular processes Cellular processes Biosynthesis of natural products capreomycidine synthase (TIGR03947; HMM-score: 45.9)
    tyrosine/nicotianamine family aminotransferase (TIGR01265; HMM-score: 31.8)
    Metabolism Energy metabolism Amino acids and amines tyrosine aminotransferase (TIGR01264; EC 2.6.1.5; HMM-score: 26.7)
    putative C-S lyase (TIGR04350; EC 4.4.-.-; HMM-score: 26.4)
    beta-methylarginine biosynthesis bifunctional aminotransferase (TIGR04544; EC 2.6.-.-; HMM-score: 19.9)
    succinyldiaminopimelate transaminase (TIGR03537; EC 2.6.1.17; HMM-score: 18.2)
    succinyldiaminopimelate transaminase (TIGR03539; EC 2.6.1.17; HMM-score: 17.8)
    LL-diaminopimelate aminotransferase (TIGR03540; EC 2.6.1.83; HMM-score: 15)
  • TheSEED: see SA2469
  • PFAM:
    PLP_aminotran (CL0061) Aminotran_1_2; Aminotransferase class I and II (PF00155; HMM-score: 123.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors: pyridoxal 5'-phosphate
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.0182
    • TAT(Tat/SPI): 0.000757
    • LIPO(Sec/SPII): 0.00112
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MIYIDKNESPVTPLDEKTMTSIISATPYNLYPDAAYEQFKEAYAKFYGLSPEQIIAGNGSDELIQKLMLIMPEGPALTLNPDFFMYQAYAAQVNREIAFVDAGSDLTFDLETILTKIDEVQPSFFIMSNPHNPSGKQFDTAFLTAIADKMKALNGYFVIDEAYLDYGTAYDVELAPHILRMRTLSKAFGIAGLRLGVLISTAGTIKHIQKIEHPYPLNVFTLNIATYIFRHREETRVFLTMQRQLAEQLKQIFDTHVADKMSVFPSNANFVLTKGSAAHQLGQYVYEQGFKPRFYDEPVMKGYVRYSIATASQLKQLEEIVKEWSAKYDLSKTTKHS

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: CodY, HisR* see SA2469

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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