PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA_RS11425 [old locus tag: SA1983 ]
• pan locus tag^?: SAUPAN005572000
• symbol: SA_RS11425
• pan gene symbol^?: sfnaD
• synonym:
• product: IucA/IucC family siderophore biosynthesis protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA_RS11425 [old locus tag: SA1983 ]
• symbol: SA_RS11425
• product: IucA/IucC family siderophore biosynthesis protein
• replicon: chromosome
• strand: +
• coordinates: 2253459..2255435
• length: 1977
• essential: no DEG other strains

⊟Accession numbers

• Location: NC_002745 (2253459..2255435) NCBI
• BioCyc: SA_RS11425 BioCyc
• MicrobesOnline: see SA1983

⊟Phenotype

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⊟DNA sequence

• 1
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  841
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  1021
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  1141
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  1621
  1681
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  1801
  1861
  1921
  
  ATGAACTTGAACTTAATTTTTAAAGAACAGACATTAAAATTTAACAAAGAAGAACAAGAA
  ACATATTTATTTTTACAACAACATAATAGCGATTGGGCTAATATTTTTAAAGAGATGATT
  TTACAAGGAAGAGATAAAGTCACTCAGAGATTAGTCACATCAATGCATCGCGAAAACTTA
  GTTAAAGCGCGCACTCAAAGTAAGAAAATATTGAGTCGTGATTTGATTATGTTAGATATC
  TCAACGACTCATATACTAGAAATCCAGTTCCCACAAGCTAAGCAAACATTATATGCTCCT
  ATCACTGGAGAACACGCCTTTGATCGAATTGATGTTGAAGGCCCTTTCTACATTAAAGAT
  GACATTACAAATACGATTACACGAGTACACCATCCAAATGAAATTCTTGAGTGTATTTTA
  ATTGAAGCACCAGATTTAAAAAATGCTGCTAGTGATCAATTTCAGCAAGATTTAATAAAC
  AGTGCAACTAATATGACATTTGCAATTAGCTATCAAGCACTGTCAATGCAACATGATTCT
  GCACCTTTATTTAATATTATCGAAAATAGCGAAGATAGTTACTTGCGTTCAGAGCAAGCC
  GTTATTGAAGGTCATCCGCTACATCCTGGGGCTAAATTACGTAAAGGTTTAAATGCATTA
  CAAACATTCCTATATTCTTCAGAATTTAATCAACCTATTAAGTTGAAAATAGTACTGATT
  CACAGTAAATTAAGTCGTACTATGTCACTGTCTAAAGATTATGATACAACTGTTCATCAG
  CTATTTCCGGACTTAATTAAACAATTAGAAAATGAATTTACGCCAAACTTTAACTTTAAT
  GATTATCACATTATGATTGTACATCCATGGCAATTAGATGACGTATTACATTCTGATTAT
  CAAGCAGAAGTAGATAAAGAATTAATCATTGAAGCAAAACATACGTTGGATTATTATGCC
  GGTTTATCTTTCAGAACATTAGTTCCTAAATACCCAGCTATGTCGCCACACATCAAATTG
  TCGACAAACGTTCATATTACAGGTGAAATTCGTACATTATCAGAACAAACGACGCACAAT
  GGTCCACTAATGACACGTATTTTAAATGATATTTTGGAGAAAGATGTCATATTTAAGTCC
  TATGCATCAACAATTATTGATGAAGTTGCTGGTATTCATTTTTATAATGAGCAAGACGAA
  GTAGACTATCAAACTGAACGAAGTGAACAATTAGGTACATTATTTAGAAAAAACATATAC
  CAAATGATTCCACAAGAAGTCACACCAATGATTCCTTCAAGCTTAGTTGCAACCTACCCA
  TTTAACAATGAATCACCTATCGTGACATTGATTAAACGTTATCAATCAGCTGCATCATTG
  TCTGATTTTGAATCATCGGCGAAATCGTGGATTGAAACTTATAGTAAAGCATTGCTTGGT
  CTCGTAATCCCACTAGTTACTAAATATGGCATTGCATTAGAGGCTCACTTGCAAAATGCT
  ATTGCAACATTTCGGAAAGATGGTCTATTGGACACGATGTATATTAGAGACTTTGAAGGT
  TTAAGAATTGATAAAGCACAACTAAATGAAATGGGATACAGTACATCTCATTTCCATGAA
  AAATCAAGAATTCTTACTGATTCAAAAACGTCTGTGTTTAACAAAGCCTTTTATTCTACC
  GTTCAAAACCATTTAGGCGAATTAATTCTTACAATCTCTAAAGCATCAAATGATTCAAAC
  TTAGAAAGACATATGTGGTATATCGTTCGTGATGTACTAGATAACATTTTTGATCAACTT
  GTACTTTCGACACACAAATCTAATCAAGTAAATGAGAATCGCATAAATGAAATTAAAGAT
  ACCATGTTCGCGCCATTTATAGATTATAAGTGTGTTACAACAATGCGTCTTGAAGATGAG
  GCACATCATTATACTTATATTAAAGTTAATAATCCTTTGTATCGAGAAAATAATTAA
  60
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  1977
  

⊟Protein

⊟General

• locus tag: SA_RS11425 [old locus tag: SA1983 ]
• symbol: SA_RS11425
• description: IucA/IucC family siderophore biosynthesis protein
• length: 658
• theoretical pI: 6.02814
• theoretical MW: 76090.9
• GRAVY: -0.367781

⊟Function

• TIGRFAM:
• TheSEED: see SA1983
• PFAM:
  PKinase (CL0016) IucA_IucC; IucA / IucC family (PF04183; HMM-score: 195.3)
  and 1 more
  no clan defined FhuF; Ferric iron reductase FhuF-like transporter (PF06276; HMM-score: 106.8)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.001636
  • TAT(Tat/SPI): 0.000276
  • LIPO(Sec/SPII): 0.000233
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 446975315 NCBI
• RefSeq: WP_001052571 NCBI
• UniProt: see SA1983

⊟Protein sequence

• MNLNLIFKEQTLKFNKEEQETYLFLQQHNSDWANIFKEMILQGRDKVTQRLVTSMHRENLVKARTQSKKILSRDLIMLDISTTHILEIQFPQAKQTLYAPITGEHAFDRIDVEGPFYIKDDITNTITRVHHPNEILECILIEAPDLKNAASDQFQQDLINSATNMTFAISYQALSMQHDSAPLFNIIENSEDSYLRSEQAVIEGHPLHPGAKLRKGLNALQTFLYSSEFNQPIKLKIVLIHSKLSRTMSLSKDYDTTVHQLFPDLIKQLENEFTPNFNFNDYHIMIVHPWQLDDVLHSDYQAEVDKELIIEAKHTLDYYAGLSFRTLVPKYPAMSPHIKLSTNVHITGEIRTLSEQTTHNGPLMTRILNDILEKDVIFKSYASTIIDEVAGIHFYNEQDEVDYQTERSEQLGTLFRKNIYQMIPQEVTPMIPSSLVATYPFNNESPIVTLIKRYQSAASLSDFESSAKSWIETYSKALLGLVIPLVTKYGIALEAHLQNAIATFRKDGLLDTMYIRDFEGLRIDKAQLNEMGYSTSHFHEKSRILTDSKTSVFNKAFYSTVQNHLGELILTISKASNDSNLERHMWYIVRDVLDNIFDQLVLSTHKSNQVNENRINEIKDTMFAPFIDYKCVTTMRLEDEAHHYTYIKVNNPLYRENN

⊟Experimental data

• experimentally validated: data available for COL, NCTC8325
• protein localization: data available for COL
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator: Fur* see SA1983

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: data available for COL

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications