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Summary[edit | edit source]

  • pan ID?: SAUPAN004814000
  • symbol?: trnaM
  • synonym:
  • description?: tRNA-Met

      descriptions from strain specific annotations:

    • tRNA-Met
    • tRNA-Ile
  • strand?: -
  • coordinates?: 5010842..5010915
  • synteny block?: BlockID0037440
  • occurrence?: in 100% of 34 strains

trnaI : tRNA-IleCAU

Modifications: [1]

• cytidine(34) → lysylcytidine(34)

Transfer RNA coding elements are organized in up to eleven loci in Staphylococcus aureus. This tRNA-IleCAU is from Locus V and, as transcribed, shares an anticodon sequence with tRNA-Met. The unique lysylcytidine(34) posttranslational modification performed by TilS as well as TilS-mediated proper isoleucyl charging of the tRNA allows this modified isoacceptor-anticodon to recognize the isoleucine codon AUA. Please note, this tRNA was not included in the panel used to detect tRNA posttranslational modifications in Staphylococcus aureus ; therefore, we are only including the known lysylcytidine modification. Other modifications are likely but not verified at this time.

Orthologs[edit | edit source]

    Newman:
    USA300_FPR3757:
    04-02981:
    SA2981_tRNA43
    08BA02176:
    C248_1918 (trnaM)
    11819-97:
    MS7_1880
    6850:
    RSAU_001733
    71193:
    ST398NM01_r029
    ECT-R 2:
    ECTR2_1718
    ED133:
    SAOV_1872c
    ED98:
    SAAV_1897
    HO 5096 0412:
    SAEMRSA15_tRNA0041
    JH1:
    SaurJH1_R0052
    JH9:
    SaurJH9_R0052
    JKD6008:
    SAA6008_t40
    JKD6159:
    SAA6159_t39
    JSNZ:
    JSNZ_001873
    LGA251:
    SARLGA251_t40
    M013:
    M013TW_1879
    MRSA252:
    SARt040
    MSHR1132:
    SAMSHR1132_t32
    MSSA476:
    SASt040
    Mu3:
    SAHV_t0041
    Mu50:
    SAVtRNA40
    MW2:
    MWtRNA40
    RF122:
    SAB_t39
    ST398:
    SAPIG1941
    T0131:
    SAT0131_t030
    TCH60:
    HMPREF0772_t10033
    TW20:
    SATW20_t400
    USA300_TCH1516:
    USA300HOU_t0040
    VC40:
    SAVC_t12545

Genome Viewer[edit | edit source]

COL
N315
NCTC8325
Newman
USA300_FPR3757

Alignments[edit | edit source]

  • alignment of orthologues:

  1. Laura Antoine, Philippe Wolff, Eric Westhof, Pascale Romby, Stefano Marzi
    Mapping post-transcriptional modifications in Staphylococcus aureus tRNAs by nanoLC/MSMS.
    Biochimie: 2019, 164;60-69
    [PubMed:31295507] [WorldCat.org] [DOI] (I p)