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⊟Summary[edit | edit source]
- pan ID?: SAUPAN004306000
- symbol?: dnaI
- synonym:
- description?: primosomal protein DnaI
- primosomal protein DnaI
- Helicase loader DnaI
- putative primosomal protein
- Replicative DNA helicase loader DnaI
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 4545090..4546010
- synteny block?: BlockID0033300
- occurrence?: in 100% of 34 strains
dnaI : primosomal helicase loader protein DnaI [1]
• A crystal structure is available : 5HE8
In staphylococci, the replicative primosomal helicase loader is called "DnaI". It is analogous to "DnaC" in E. coli and other organisms.
⊟Orthologs[edit | edit source]
04-02981:
SA2981_1643 (dnaI)
08BA02176:
C248_1726 (dnaI)
11819-97:
MS7_1691 (dnaI)
6850:
RSAU_001542 (dnaI)
71193:
ST398NM01_1738
ECT-R 2:
ECTR2_1524
ED133:
SAOV_1672 (dnaI)
ED98:
SAAV_1674 (dnaI)
HO 5096 0412:
SAEMRSA15_15940 (dnaI)
JH1:
SaurJH1_1775
JH9:
SaurJH9_1741
JKD6008:
SAA6008_01651 (dnaI)
JKD6159:
SAA6159_01608 (dnaI)
LGA251:
SARLGA251_15760 (dnaI)
M013:
M013TW_1697
MRSA252:
SAR1763 (dnaI)
MSHR1132:
SAMSHR1132_15110
MSSA476:
SAS1612
Mu3:
SAHV_1670 (dnaI)
Mu50:
SAV1684 (dnaI)
MW2:
MW1627 (dnaI)
RF122:
SAB1543c (dnaI)
ST398:
SAPIG1738
T0131:
SAT0131_01786
TCH60:
HMPREF0772_11467 (dnaI)
TW20:
SATW20_16740 (dnaI)
USA300_TCH1516:
USA300HOU_1671 (dnaI)
VC40:
SAVC_07625
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 | |
| JSNZ |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MKQFKSIINTSQDFEKRIEKIKKEVINDPDVKQFLEAHRAELTNAMIDEDLNVLQEYKDQ
N315 MKQFKSIINTSQDFEKRIEKIKKEVINDPDVKQFLEAHRAELTNAMIDEDLNVLQEYKDQ
NCTC8325 MKQFKSIINTSQDFEKRIEKIKKEVINDPDVKQFLEAHRAELTNAMIDEDLNVLQEYKDQ
Newman MKQFKSIINTSQDFEKRIEKIKKEVINDPDVKQFLEAHRAELTNAMIDEDLNVLQEYKDQ
USA300_FPR3757 MKQFKSIINTSQDFEKRIEKIKKEVINDPDVKQFLEAHRAELTNAMIDEDLNVLQEYKDQ
************************************************************
COL QKHYDGHKFADCPNFVKGHVPELYVDNNRIKIRYLQCPCKIKYDEERFEAELITSHHMQR
N315 QKHYDGHKFADCPNFVKGHVPELYVDNNRIKIRYLQCPCKIKYDEERFEAELITSHHMQR
NCTC8325 QKHYDGHKFADCPNFVKGHVPELYVDNNRIKIRYLQCPCKIKYDEERFEAELITSHHMQR
Newman QKHYDGHKFADCPNFVKGHVPELYVDNNRIKIRYLQCPCKIKYDEERFEAELITSHHMQR
USA300_FPR3757 QKHYDGHKFADCPNFVKGHVPELYVDNNRIKIRYLQCPCKIKYDEERFEAELITSHHMQR
************************************************************
COL DTLNAKLKDIYMNHRDRLDVAMAADDICTAITNGEQVKGLYLYGPFGTGKSFILGAIANQ
N315 DTLNAKLKDIYMNHRDRLDVAMAADDICTAITNGEQVKGLYLYGPFGTGKSFILGAIANQ
NCTC8325 DTLNAKLKDIYMNHRDRLDVAMAADDICTAITNGEQVKGLYLYGPFGTGKSFILGAIANQ
Newman DTLNAKLKDIYMNHRDRLDVAMAADDICTAITNGEQVKGLYLYGPFGTGKSFILGAIANQ
USA300_FPR3757 DTLNAKLKDIYMNHRDRLDVAMAADDICTAITNGEQVKGLYLYGPFGTGKSFILGAIANQ
************************************************************
COL LKSKKVRSTIIYLPEFIRTLKGGFKDGSFEKKLHRVREANILMLDDIGAEEVTPWVRDEV
N315 LKSKKVRSTIIYLPEFIRTLKGGFKDGSFEKKLHRVREANILMLDDIGAEEVTPWVRDEV
NCTC8325 LKSKKVRSTIIYLPEFIRTLKGGFKDGSFEKKLHRVREANILMLDDIGAEEVTPWVRDEV
Newman LKSKKVRSTIIYLPEFIRTLKGGFKDGSFEKKLHRVREANILMLDDIGAEEVTPWVRDEV
USA300_FPR3757 LKSKKVRSTIIYLPEFIRTLKGGFKDGSFEKKLHRVREANILMLDDIGAEEVTPWVRDEV
************************************************************
COL IGPLLHYRMVHELPTFFSSNFDYSELEHHLAMTRDGEEKTKAARIIERVKSLSTPYFLSG
N315 IGPLLHYRMVHELPTFFSSNFDYSELEHHLAMTRDGEEKTKAARIIERVKSLSTPYFLSG
NCTC8325 IGPLLHYRMVHELPTFFSSNFDYSELEHHLAMTRDGEEKTKAARIIERVKSLSTPYFLSG
Newman IGPLLHYRMVHELPTFFSSNFDYSELEHHLAMTRDGEEKTKAARIIERVKSLSTPYFLSG
USA300_FPR3757 IGPLLHYRMVHELPTFFSSNFDYSELEHHLAMTRDGEEKTKAARIIERVKSLSTPYFLSG
************************************************************
COL ENFRNN
N315 ENFRNN
NCTC8325 ENFRNN
Newman ENFRNN
USA300_FPR3757 ENFRNN
******
- ↑ Yan Li, Kenji Kurokawa, Luzia Reutimann, Hikaru Mizumura, Miki Matsuo, Kazuhisa Sekimizu
DnaB and DnaI temperature-sensitive mutants of Staphylococcus aureus: evidence for involvement of DnaB and DnaI in synchrony regulation of chromosome replication.
Microbiology (Reading): 2007, 153(Pt 10);3370-3379
[PubMed:17906136] [WorldCat.org] [DOI] (P p)Iris V Hood, James M Berger
Viral hijacking of a replicative helicase loader and its implications for helicase loading control and phage replication.
Elife: 2016, 5;
[PubMed:27244442] [WorldCat.org] [DOI] (I e)