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Summary[edit | edit source]

  • pan ID?: SAUPAN004132000
  • symbol?: rpmG
  • synonym:
  • description?: 50S ribosomal protein L33

      descriptions from strain specific annotations:

    • 50S ribosomal protein L33
    • 50S ribosomal protein L33p
    • 50S ribosomal protein L33 type 1
  • strand?: -
  • coordinates?: 4400347..4400496
  • synteny block?: BlockID0031620
  • occurrence?: in 100% of 33 strains

rpmG1 : 50S ribosomal protein L33 [1]

• Two crystal structures are available : 6YEF , 5ND8

Staphylococci have two copies of rpmG. rpmG1 is next to the gene encoding penicillin binding protein 3 while rpmG2 is next to the gene encoding catalase. Although 90% identical / 94% similar, the two paralogues often differ at positions 30, 35, 37, 39 and 42. Although both forms appear to be functional in ribosomes and found in crystal structures, it appears that only rpmG1 is essential.

Orthologs[edit | edit source]

    COL:
    SACOL1608 (rpmG)
    N315:
    SAS047 (rpmG)
    NCTC8325:
    Newman:
    NWMN_1454 (rpmG)
    USA300_FPR3757:
    04-02981:
    SA2981_1509 (rpmG)
    08BA02176:
    C248_1594 (rpmG1)
    11819-97:
    MS7_1568
    6850:
    RSAU_001416 (rpmG3)
    71193:
    ST398NM01_1616
    ECT-R 2:
    ECTR2_1401 (rpmG)
    ED133:
    SAOV_1551 (rpmG_2)
    ED98:
    SAAV_1543 (rpmG_1)
    HO 5096 0412:
    SAEMRSA15_14710 (rpmG1)
    JH1:
    SaurJH1_1643 (rpmG)
    JH9:
    SaurJH9_1609 (rpmG)
    JKD6008:
    SAA6008_01520 (rpmG)
    JKD6159:
    SAA6159_01486 (rpmG)
    LGA251:
    SARLGA251_14570 (rpmG1)
    M013:
    M013TW_1566
    MRSA252:
    SAR1628 (rpmG)
    MSHR1132:
    SAMSHR1132_13910
    MSSA476:
    SAS1489 (rpmG)
    Mu3:
    SAHV_1538 (rpmG)
    Mu50:
    SAV1551 (rpmG)
    MW2:
    MW1503 (rpmG)
    RF122:
    SAB1423c (rpmG)
    ST398:
    SAPIG1616 (rpmG)
    T0131:
    SAT0131_01645
    TCH60:
    HMPREF0772_11589 (rpmG)
    TW20:
    SATW20_15470 (rpmG1)
    USA300_TCH1516:
    USA300HOU_1553 (rpmG)
    VC40:
    SAVC_07005 (rpmG)

Genome Viewer[edit | edit source]

COL
N315
NCTC8325
Newman
USA300_FPR3757

Alignments[edit | edit source]

  • alignment of orthologues:
    CLUSTAL format alignment by MAFFT L-INS-i (v7.307)


    COL             MRVNVTLACTECGDRNYITTKNKRNNPERVEMKKFCSRENKQTLHRETK
    N315            MRVNVTLACTECGDRNYITTKNKRNNPERVEMKKFCSRENKQTLHRETK
    NCTC8325        MRVNVTLACTECGDRNYITTKNKRNNPERVEMKKFCSRENKQTLHRETK
    Newman          MRVNVTLACTECGDRNYITTKNKRNNPERVEMKKFCSRENKQTLHRETK
    USA300_FPR3757  MRVNVTLACTECGDRNYITTKNKRNNPERVEMKKFCSRENKQTLHRETK
                    *************************************************

  1. José Francisco Sanchez-Herrero, Manuel Bernabeu, Alejandro Prieto, Mário Hüttener, Antonio Juárez
    Gene Duplications in the Genomes of Staphylococci and Enterococci.
    Front Mol Biosci: 2020, 7;160
    [PubMed:32850954] [WorldCat.org] [DOI] (P e)
    Alexander Golubev, Bulat Fatkhullin, Iskander Khusainov, Lasse Jenner, Azat Gabdulkhakov, Shamil Validov, Gulnara Yusupova, Marat Yusupov, Konstantin Usachev
    Cryo-EM structure of the ribosome functional complex of the human pathogen Staphylococcus aureus at 3.2 Å resolution.
    FEBS Lett: 2020, 594(21);3551-3567
    [PubMed:32852796] [WorldCat.org] [DOI] (I p)