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⊟Summary[edit | edit source]
- pan ID?: SAUPAN004025000
- symbol?: srrA
- synonym:
- description?: DNA-binding response regulator
- DNA-binding response regulator
- DNA-binding response regulator SrrA
- respiratory response protein, SrrA
- respiratory response protein SrrA
- response regulator transcription factor
- two-component system response regulator SrrA
- transcriptional regulatory protein SrrA
- transcriptional regulatory protein resD
- DNA-binding response regulator ResD
- pseudogene
- respiratory response protein
- response regulator protein
- response regulator receiver
- Staphylococcal respiratory response protein SrrA
- two component transcriptional regulator
- winged helix family two component transcriptional regulator
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 4316437..4317162
- synteny block?: BlockID0030620
- occurrence?: in 100% of 34 strains
srrA : staphylococcal respiratory response response regulator [1]
⊟Orthologs[edit | edit source]
04-02981:
SA2981_1449 (srrA)
08BA02176:
C248_1532 (srrA)
11819-97:
MS7_1509 (srrA)
6850:
RSAU_001360 (srrA)
71193:
ST398NM01_1558
ECT-R 2:
ECTR2_1343
ED133:
SAOV_1494
ED98:
SAAV_1482 (srrA)
HO 5096 0412:
SAEMRSA15_14140 (srrA)
JH1:
SaurJH1_1580
JH9:
SaurJH9_1549
JKD6008:
SAA6008_01462 (srrA)
JKD6159:
SAA6159_01421 (srrA)
JSNZ:
JSNZ_001480 (srrA)
LGA251:
SARLGA251_14000 (srrA)
M013:
M013TW_1506
MRSA252:
SAR1568 (srrA)
MSHR1132:
SAMSHR1132_13310
MSSA476:
SAS1432
Mu3:
SAHV_1480 (srrA)
Mu50:
SAV1492 (srrA)
MW2:
MW1446 (srrA)
RF122:
SAB1353c (srrA)
ST398:
SAPIG1558
T0131:
SAT0131_01585
TCH60:
HMPREF0772_11649 (srrA)
TW20:
SATW20_14900 (srrA)
USA300_TCH1516:
USA300HOU_1494 (srrA)
VC40:
SAVC_06710
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MSNEILIVDDEDRIRRLLKMYLERESFEIHEASNGQEAYELAMENNYACILLDLMLPEMD
N315 MSNEILIVDDEDRIRRLLKMYLERESFEIHEASNGQEAYELAMENNYACILLDLMLPEMD
NCTC8325 MSNEILIVDDEDRIRRLLKMYLERESFEIHEASNGQEAYELAMENNYACILLDLMLPEMD
Newman MSNEILIVDDEDRIRRLLKMYLERESFEIHEASNGQEAYELAMENNYACILLDLMLPEMD
USA300_FPR3757 MSNEILIVDDEDRIRRLLKMYLERESFEIHEASNGQEAYELAMENNYACILLDLMLPEMD
************************************************************
COL GIQVATKLREHKQTPIIMLTAKGEETNRVEGFESGADDYIVKPFSPREVVLRVKALLRRT
N315 GIQVATKLREHKQTPIIMLTAKGEETNRVEGFESGADDYIVKPFSPREVVLRVKALLRRT
NCTC8325 GIQVATKLREHKQTPIIMLTAKGEETNRVEGFESGADDYIVKPFSPREVVLRVKALLRRT
Newman GIQVATKLREHKQTPIIMLTAKGEETNRVEGFESGADDYIVKPFSPREVVLRVKALLRRT
USA300_FPR3757 GIQVATKLREHKQTPIIMLTAKGEETNRVEGFESGADDYIVKPFSPREVVLRVKALLRRT
************************************************************
COL QSTTVEQSEPHARDVIEFKHLEIDNDAHRVLADNQEVNLTPKEYELLIYLAKTPNKVFDR
N315 QSTTVEQSEPHARDVIEFKHLEIDNDAHRVLADNQEVNLTPKEYELLIYLAKTPNKVFDR
NCTC8325 QSTTVEQSEPHARDVIEFKHLEIDNDAHRVLADNQEVNLTPKEYELLIYLAKTPNKVFDR
Newman QSTTVEQSEPHARDVIEFKHLEIDNDAHRVLADNQEVNLTPKEYELLIYLAKTPNKVFDR
USA300_FPR3757 QSTTVEQSEPHARDVIEFKHLEIDNDAHRVLADNQEVNLTPKEYELLIYLAKTPNKVFDR
************************************************************
COL EQLLKEVWHYEFYGDLRTVDTHVKRLREKLNRVSSEAAHMIQTVWGVGYKFEVKSNDEPA
N315 EQLLKEVWHYEFYGDLRTVDTHVKRLREKLNRVSSEAAHMIQTVWGVGYKFEVKSNDEPA
NCTC8325 EQLLKEVWHYEFYGDLRTVDTHVKRLREKLNRVSSEAAHMIQTVWGVGYKFEVKSNDEPA
Newman EQLLKEVWHYEFYGDLRTVDTHVKRLREKLNRVSSEAAHMIQTVWGVGYKFEVKSNDEPA
USA300_FPR3757 EQLLKEVWHYEFYGDLRTVDTHVKRLREKLNRVSSEAAHMIQTVWGVGYKFEVKSNDEPA
************************************************************
COL K
N315 K
NCTC8325 K
Newman K
USA300_FPR3757 K
*
- ↑ Alexa A Pragman, Jeremy M Yarwood, Timothy J Tripp, Patrick M Schlievert
Characterization of virulence factor regulation by SrrAB, a two-component system in Staphylococcus aureus.
J Bacteriol: 2004, 186(8);2430-8
[PubMed:15060046] [WorldCat.org] [DOI] (P p)Nitija Tiwari, Marisa López-Redondo, Laura Miguel-Romero, Katarina Kulhankova, Michael P Cahill, Phuong M Tran, Kyle J Kinney, Samuel H Kilgore, Hassan Al-Tameemi, Christine A Herfst, Stephen W Tuffs, John R Kirby, Jeffery M Boyd, John K McCormick, Wilmara Salgado-Pabón, Alberto Marina, Patrick M Schlievert, Ernesto J Fuentes
The SrrAB two-component system regulates Staphylococcus aureus pathogenicity through redox sensitive cysteines.
Proc Natl Acad Sci U S A: 2020, 117(20);10989-10999
[PubMed:32354997] [WorldCat.org] [DOI] (I p)Lisa Bleul, Patrice Francois, Christiane Wolz
Two-Component Systems of S. aureus: Signaling and Sensing Mechanisms.
Genes (Basel): 2021, 13(1);
[PubMed:35052374] [WorldCat.org] [DOI] (I e)