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NCBI: 26-AUG-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus N315
- locus tag: SA1323 [new locus tag: SA_RS07505 ]
- pan locus tag?: SAUPAN004025000
- symbol: srrA
- pan gene symbol?: srrA
- synonym:
- product: respiratory response protein SrrA
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SA1323 [new locus tag: SA_RS07505 ]
- symbol: srrA
- product: respiratory response protein SrrA
- replicon: chromosome
- strand: -
- coordinates: 1532571..1533296
- length: 726
- essential: no DEG other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 1124163 NCBI
- RefSeq: NP_374606 NCBI
- BioCyc: see SA_RS07505
- MicrobesOnline: 103632 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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721ATGTCGAACGAAATACTTATCGTAGATGATGAGGATAGAATCAGAAGATTACTTAAAATG
TATTTAGAAAGAGAATCTTTTGAAATCCATGAAGCAAGTAATGGCCAAGAGGCTTATGAA
CTTGCAATGGAGAATAATTATGCTTGCATACTACTAGATTTAATGTTGCCTGAAATGGAT
GGTATCCAGGTGGCAACTAAATTGCGTGAACATAAACAAACACCGATTATTATGTTGACT
GCTAAAGGTGAAGAAACAAACCGTGTTGAAGGTTTTGAATCTGGTGCAGATGATTATATC
GTCAAACCATTTTCACCAAGAGAAGTAGTCTTAAGAGTTAAAGCACTTCTAAGAAGAACG
CAATCTACAACTGTAGAACAAAGCGAACCTCACGCACGTGATGTGATTGAATTTAAACAT
TTAGAAATAGATAATGATGCACATCGCGTACTTGCTGATAATCAAGAAGTTAATTTGACT
CCTAAAGAGTACGAATTATTAATATATTTAGCTAAAACACCAAATAAAGTATTTGACCGT
GAACAATTATTAAAAGAAGTTTGGCATTATGAATTCTATGGTGATTTAAGAACAGTTGAT
ACTCATGTTAAACGACTTAGAGAAAAGTTAAATCGTGTGTCTAGCGAAGCTGCGCATATG
ATTCAAACAGTCTGGGGCGTTGGGTATAAATTTGAGGTTAAATCTAATGATGAGCCGGCT
AAATAG60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SA1323 [new locus tag: SA_RS07505 ]
- symbol: SrrA
- description: respiratory response protein SrrA
- length: 241
- theoretical pI: 5.02595
- theoretical MW: 28160.8
- GRAVY: -0.575519
⊟Function[edit | edit source]
- TIGRFAM: Regulatory functions DNA interactions phosphate regulon transcriptional regulatory protein PhoB (TIGR02154; HMM-score: 245.3)Signal transduction Two-component systems phosphate regulon transcriptional regulatory protein PhoB (TIGR02154; HMM-score: 245.3)and 8 moreRegulatory functions DNA interactions heavy metal response regulator (TIGR01387; HMM-score: 182.9)proteobacterial dedicated sortase system response regulator (TIGR03787; HMM-score: 115.6)Cellular processes Sporulation and germination sporulation transcription factor Spo0A (TIGR02875; HMM-score: 69.2)Central intermediary metabolism Nitrogen metabolism nitrogen regulation protein NR(I) (TIGR01818; HMM-score: 59)Regulatory functions DNA interactions nitrogen regulation protein NR(I) (TIGR01818; HMM-score: 59)Signal transduction Two-component systems nitrogen regulation protein NR(I) (TIGR01818; HMM-score: 59)Signal transduction Two-component systems TMAO reductase sytem sensor TorS (TIGR02956; EC 2.7.13.3; HMM-score: 34.9)Regulatory functions DNA interactions PEP-CTERM-box response regulator transcription factor (TIGR02915; HMM-score: 31.6)
- TheSEED :
- DNA-binding response regulator ResD
- PFAM: CheY (CL0304) Response_reg; Response regulator receiver domain (PF00072; HMM-score: 111.7)HTH (CL0123) Trans_reg_C; Transcriptional regulatory protein, C terminal (PF00486; HMM-score: 97.9)and 1 moreGerE; Bacterial regulatory proteins, luxR family (PF00196; HMM-score: 12.6)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 10
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 0
- LocateP: Intracellular
- Prediction by SwissProt Classification: Cytoplasmic
- Pathway Prediction: No pathway
- Intracellular possibility: 1
- Signal peptide possibility: -1
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.001191
- TAT(Tat/SPI): 0.000151
- LIPO(Sec/SPII): 0.000213
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MSNEILIVDDEDRIRRLLKMYLERESFEIHEASNGQEAYELAMENNYACILLDLMLPEMDGIQVATKLREHKQTPIIMLTAKGEETNRVEGFESGADDYIVKPFSPREVVLRVKALLRRTQSTTVEQSEPHARDVIEFKHLEIDNDAHRVLADNQEVNLTPKEYELLIYLAKTPNKVFDREQLLKEVWHYEFYGDLRTVDTHVKRLREKLNRVSSEAAHMIQTVWGVGYKFEVKSNDEPAK
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator: Rex* (repression) regulon
Rex* (TF) important in Energy metabolism; RegPrecise
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
⊟Relevant publications[edit | edit source]
Alexander Scherl, Patrice François, Manuela Bento, Jacques M Deshusses, Yvan Charbonnier, Véronique Converset, Antoine Huyghe, Nadia Walter, Christine Hoogland, Ron D Appel, Jean-Charles Sanchez, Catherine G Zimmermann-Ivol, Garry L Corthals, Denis F Hochstrasser, Jacques Schrenzel
Correlation of proteomic and transcriptomic profiles of Staphylococcus aureus during the post-exponential phase of growth.
J Microbiol Methods: 2005, 60(2);247-57
[PubMed:15590099] [WorldCat.org] [DOI] (P p)