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⊟Summary[edit | edit source]
- pan ID?: SAUPAN003904000
- symbol?: gpsB
- synonym:
- description?: cell cycle protein GpsB
- cell cycle protein GpsB
- cell division regulator GpsB
- cell division initiation protein DivIVA
- cell division protein diviva
- cell division protein GpsB
- Cell division protein GpsB, coordinates the switch between cylindrical and septal cell wall synthesis by re-localization of PBP1
- divIVA family protein
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 4224882..4225226
- synteny block?: BlockID0029500
- occurrence?: in 100% of 33 strains
gpsB: transpeptidase septal sequestration protein [1]
⊟Orthologs[edit | edit source]
04-02981:
SA2981_1401 (gpsB)
08BA02176:
C248_1485
11819-97:
MS7_1402 (gpsB)
6850:
RSAU_001318 (gpsB)
71193:
ST398NM01_1445
ECT-R 2:
ECTR2_1300
ED133:
SAOV_1454
ED98:
SAAV_1431
HO 5096 0412:
SAEMRSA15_13070
JH1:
SaurJH1_1534
JH9:
SaurJH9_1505
JKD6008:
SAA6008_01414 (gpsB)
JKD6159:
SAA6159_01311 (gpsB)
LGA251:
SARLGA251_13600
M013:
M013TW_1393
MRSA252:
SAR1457
MSHR1132:
SAMSHR1132_12860
MSSA476:
SAS1388
Mu3:
SAHV_1434
Mu50:
SAV1446
MW2:
MW1335
RF122:
SAB1310c
ST398:
SAPIG1445
T0131:
SAT0131_01534
TCH60:
HMPREF0772_11759 (divIVA)
TW20:
SATW20_14450
USA300_TCH1516:
USA300HOU_1383
VC40:
SAVC_06485
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MSDVSLKLSAKDIYEKDFEKTMARGYRREEVDAFLDDIIADYQKMADMNNEVVKLSEENH
N315 MSDVSLKLSAKDIYEKDFEKTMARGYRREEVDAFLDDIIADYQKMADMNNEVVKLSEENH
NCTC8325 MSDVSLKLSAKDIYEKDFEKTMARGYRREEVDAFLDDIIADYQKMADMNNEVVKLSEENH
Newman MSDVSLKLSAKDIYEKDFEKTMARGYRREEVDAFLDDIIADYQKMADMNNEVVKLSEENH
USA300_FPR3757 MSDVSLKLSAKDIYEKDFEKTMARGYRREEVDAFLDDIIADYQKMADMNNEVVKLSEENH
************************************************************
COL KLKKELEELRLRVATSRPQDNKSFSSNNTTTNTSSNNVDILKRISNLEKAVFGK
N315 KLKKELEELRLRVATSRPQDNKSFSSNNTTTNTSSNNVDILKRISNLEKAVFGK
NCTC8325 KLKKELEELRLRVATSRPQDNKSFSSNNTTTNTSSNNVDILKRISNLEKAVFGK
Newman KLKKELEELRLRVATSRPQDNKSFSSNNTTTNTSSNNVDILKRISNLEKAVFGK
USA300_FPR3757 KLKKELEELRLRVATSRPQDNKSFSSNNTTTNTSSNNVDILKRISNLEKAVFGK
******************************************************
- ↑ Prahathees J Eswara, Robert S Brzozowski, Marissa G Viola, Gianni Graham, Catherine Spanoudis, Catherine Trebino, Jyoti Jha, Joseph I Aubee, Karl M Thompson, Jodi L Camberg, Kumaran S Ramamurthi
An essential Staphylococcus aureus cell division protein directly regulates FtsZ dynamics.
Elife: 2018, 7;
[PubMed:30277210] [WorldCat.org] [DOI] (I e)Lauren R Hammond, Michael D Sacco, Sebastian J Khan, Catherine Spanoudis, Abigail Hough-Neidig, Yu Chen, Prahathees J Eswara
GpsB Coordinates Cell Division and Cell Surface Decoration by Wall Teichoic Acids in Staphylococcus aureus.
Microbiol Spectr: 2022, 10(3);e0141322
[PubMed:35647874] [WorldCat.org] [DOI] (I p)Sara F Costa, Bruno M Saraiva, Helena Veiga, Leonor B Marques, Simon Schäper, Marta Sporniak, Daniel E Vega, Ana M Jorge, Andreia M Duarte, António D Brito, Andreia C Tavares, Patricia Reed, Mariana G Pinho
The role of GpsB in Staphylococcus aureus cell morphogenesis.
mBio: 2024, 15(3);e0323523
[PubMed:38319093] [WorldCat.org] [DOI] (I p)Michael D Sacco, Lauren R Hammond, Radwan E Noor, Dipanwita Bhattacharya, Lily J McKnight, Jesper J Madsen, Xiujun Zhang, Shane G Butler, M Trent Kemp, Aiden C Jaskolka-Brown, Sebastian J Khan, Ioannis Gelis, Prahathees Eswara, Yu Chen
Staphylococcus aureus FtsZ and PBP4 bind to the conformationally dynamic N-terminal domain of GpsB.
Elife: 2024, 13;
[PubMed:38639993] [WorldCat.org] [DOI] (I e)