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⊟Summary[edit | edit source]
- pan ID?: SAUPAN003857000
- symbol?: fakB2
- synonym:
- description?: DegV family protein
- DegV family protein
- fatty acid kinase binding subunit FakB2
- fatty acid kinase FakB2
- DegVA
- degV domain-containing protein
- DegV domain-containing protein MW1315
- fatty acid-binding protein, DegV family
- putative fatty acid-binding protein
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 4138827..4139666
- synteny block?: BlockID0029130
- occurrence?: in 100% of 34 strains
fakB2 : unsaturated fatty acid binding protein [1]
• A crystal structure is available : 4X9X
FakB2 binds to long-chain unsaturated fatty acids such as palmitate and may play roles in substrate solubilization, transport or enzyme recognition.
⊟Orthologs[edit | edit source]
04-02981:
SA2981_1379
08BA02176:
C248_1465
11819-97:
MS7_1381
6850:
RSAU_001304
71193:
ST398NM01_1426
ECT-R 2:
ECTR2_1281
ED133:
SAOV_1434c
ED98:
SAAV_1408
HO 5096 0412:
SAEMRSA15_12880
JH1:
SaurJH1_1514
JH9:
SaurJH9_1485
JKD6008:
SAA6008_01393
JKD6159:
SAA6159_01292
JSNZ:
JSNZ_001410 (fakB2)
LGA251:
SARLGA251_13410
M013:
M013TW_1371
MRSA252:
SAR1438
MSHR1132:
SAMSHR1132_12670
MSSA476:
SAS1368
Mu3:
SAHV_1413
Mu50:
SAV1425
MW2:
MW1315
RF122:
SAB1280c
ST398:
SAPIG1426
T0131:
SAT0131_01505 (pbuX)
TCH60:
HMPREF0772_11781
TW20:
SATW20_14260
USA300_TCH1516:
USA300HOU_1362
VC40:
SAVC_06375
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MTKQIIVTDSTSDLSKEYLEANNIHVIPLSLTIEGASYVDQVDITSEEFINHIENDEDVK
N315 MTKQIIVTDSTSDLSKEYLEANNIHVIPLSLTIEGASYVDQVDITSEEFINHIENDEDVK
NCTC8325 MTKQIIVTDSTSDLSKEYLEANNIHVIPLSLTIEGASYVDQVDITSEEFINHIENDEDVK
Newman MTKQIIVTDSTSDLSKEYLEANNIHVIPLSLTIEGASYVDQVDITSEEFINHIENDEDVK
USA300_FPR3757 MTKQIIVTDSTSDLSKEYLEANNIHVIPLSLTIEGASYVDQVDITSEEFINHIENDEDVK
************************************************************
COL TSQPAIGEFISAYEELGKDGSEIISIHLSSGLSGTYNTAYQASQMVDANVTVIDSKSISF
N315 TSQPAIGEFISAYEELGKDGSEIISIHLSSGLSGTYNTAYQASQMVDANVTVIDSKSISF
NCTC8325 TSQPAIGEFISAYEELGKDGSEIISIHLSSGLSGTYNTAYQASQMVDANVTVIDSKSISF
Newman TSQPAIGEFISAYEELGKDGSEIISIHLSSGLSGTYNTAYQASQMVDANVTVIDSKSISF
USA300_FPR3757 TSQPAIGEFISAYEELGKDGSEIISIHLSSGLSGTYNTAYQASQMVDANVTVIDSKSISF
************************************************************
COL GLGYQIQHLVELVKEGVSTSEIVKKLNHLRENIKLFVVIGQLNQLIKGGRISKTKGLIGN
N315 SLGYQIQHLVELVKEGVSTSEIVKKLNHLRENIKLFVVIGQLNQLIKGGRISKTKGLIGN
NCTC8325 GLGYQIQHLVELVKEGVSTSEIVKKLNHLRENIKLFVVIGQLNQLIKGGRISKTKGLIGN
Newman GLGYQIQHLVELVKEGVSTSEIVKKLNHLRENIKLFVVIGQLNQLIKGGRISKTKGLIGN
USA300_FPR3757 GLGYQIQHLVELVKEGVSTSEIVKKLNHLRENIKLFVVIGQLNQLIKGGRISKTKGLIGN
.***********************************************************
COL LMKIKPIGTLDDGRLELVHNARTQNSSIQYLKKEIAEFIGDHEIKSIGVAHANVIEYVDK
N315 LMKIKPIGTLDDGRLELVHNARTQNSSIQYLKKEIAEFIGDHEIKSIGVAHANVIEYVDK
NCTC8325 LMKIKPIGTLDDGRLELVHNARTQNSSIQYLKKEIAEFIGDHEIKSIGVAHANVIEYVDK
Newman LMKIKPIGTLDDGRLELVHNARTQNSSIQYLKKEIAEFIGDHEIKSIGVAHANVIEYVDK
USA300_FPR3757 LMKIKPIGTLDDGRLELVHNARTQNSSIQYLKKEIAEFIGDHEIKSIGVAHANVIEYVDK
************************************************************
COL LKKVFNEAFHVNNYDINVTTPVISAHTGQGAIGLVVLKK
N315 LKKVFNEAFHVNNYDINVTTPVISAHTGQGAIGLVVLKK
NCTC8325 LKKVFNEAFHVNNYDINVTTPVISAHTGQGAIGLVVLKK
Newman LKKVFNEAFHVNNYDINVTTPVISAHTGQGAIGLVVLKK
USA300_FPR3757 LKKVFNEAFHVNNYDINVTTPVISAHTGQGAIGLVVLKK
***************************************
- ↑ Joshua B Parsons, Tyler C Broussard, Jeffrey L Bose, Jason W Rosch, Pamela Jackson, Chitra Subramanian, Charles O Rock
Identification of a two-component fatty acid kinase responsible for host fatty acid incorporation by Staphylococcus aureus.
Proc Natl Acad Sci U S A: 2014, 111(29);10532-7
[PubMed:25002480] [WorldCat.org] [DOI] (I p)Maxime G Cuypers, Chitra Subramanian, Jessica M Gullett, Matthew W Frank, Stephen W White, Charles O Rock
Acyl-chain selectivity and physiological roles of Staphylococcus aureus fatty acid-binding proteins.
J Biol Chem: 2019, 294(1);38-49
[PubMed:30429218] [WorldCat.org] [DOI] (I p)