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⊟Summary[edit | edit source]
- pan ID?: SAUPAN003770000
- symbol?: femB
- synonym:
- description?: aminoacyltransferase FemB
- aminoacyltransferase FemB
- femB protein
- glycine glycyltransferase FemB
- methicillin resistance protein FemB
- methicillin resistance expression factor FemB
- methicillin resistance factor
- putative methicillin resistance expressionfactor
- aminoacyltransferase FemB (Factor essential forexpression of methicillin resistance B)
- femAB family protein
- FemB, factor involved in methicillin resistance / Glycine interpeptide bridge formation
- glycine interpeptide bridge formation protein FemB
- methicillin resistance factor FemB
- methicillin resistance factor protein
- methicillin resistance protein
- UDP-N-acetylmuramoylpentapeptide-triglycine glycyltransferase
descriptions from strain specific annotations:
- strand?: +
- coordinates?: 4067726..4068985
- synteny block?: BlockID0028320
- occurrence?: in 100% of 34 strains
femB : lipid II-tripeptide:glycylglycine aminoacyltransferase [1]
⊟Orthologs[edit | edit source]
04-02981:
SA2981_1329 (femB)
08BA02176:
C248_1413 (femB)
11819-97:
MS7_1332 (femB)
6850:
RSAU_001256 (femB)
71193:
ST398NM01_1376
ECT-R 2:
ECTR2_1232
ED133:
SAOV_1385
ED98:
SAAV_1357
HO 5096 0412:
SAEMRSA15_12230 (femB)
JH1:
SaurJH1_1465
JH9:
SaurJH9_1436
JKD6008:
SAA6008_01340 (femB)
JKD6159:
SAA6159_01242 (femB)
LGA251:
SARLGA251_12840 (femB)
M013:
M013TW_1321
MRSA252:
SAR1388 (femB)
MSHR1132:
SAMSHR1132_12180
MSSA476:
SAS1315
Mu3:
SAHV_1363 (femB)
Mu50:
SAV1375 (femB)
MW2:
MW1262 (femB)
RF122:
SAB1230 (femB)
ST398:
SAPIG1376
T0131:
SAT0131_01447 (bioX)
TCH60:
HMPREF0772_11832 (femB)
TW20:
SATW20_13750 (femB)
USA300_TCH1516:
USA300HOU_1310 (femB)
VC40:
SAVC_06125
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 | |
| JSNZ |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MKFTELTVTEFDNFVQNPSLESHYFQVKENIVTRENDGFEVVLLGIKDDNNKVIAASLFS
N315 MKFTELTVTEFDNFVQNPSLESHYFQVKENIVTRENDGFEVVLLGIKDDNNKVIAASLFS
NCTC8325 MKFTELTVTEFDNFVQNPSLESHYFQVKENIVTRENDGFEVVLLGIKDDNNKVIAASLFS
Newman MKFTELTVTEFDNFVQNPSLESHYFQVKENIVTRENDGFEVVLLGIKDDNNKVIAASLFS
USA300_FPR3757 MKFTELTVTEFDNFVQNPSLESHYFQVKENIVTRENDGFEVVLLGIKDDNNKVIAASLFS
************************************************************
COL KIPTMGSYVYYSNRGPVMDFSDLGLVDYYLKELDKYLQQHQCLYVKLDPYWLYHLYDKDI
N315 KIPTMGSYVYYSNRGPVMDFSDLGLVDYYLKELDKYLQQHQCLYVKLDPYWLYHLYDKDI
NCTC8325 KIPTMGSYVYYSNRGPVMDFSDLGLVDYYLKELDKYLQQHQCLYVKLDPYWLYHLYDKDI
Newman KIPTMGSYVYYSNRGPVMDFSDLGLVDYYLKELDKYLQQHQCLYVKLDPYWLYHLYDKDI
USA300_FPR3757 KIPTMGSYVYYSNRGPVMDFSDLGLVDYYLKELDKYLQQHQCLYVKLDPYWLYHLYDKDI
************************************************************
COL VPFEGREKNDALVNLFKSHGYEHHGFTTEYDTSSQVRWMGVLNLEGKTPETLKKTFDSQR
N315 VPFEGREKNDALVNLFKSHGYEHHGFTTEYDTSSQVRWMGVLNLEGKTPETLKKTFDSQR
NCTC8325 VPFEGREKNDALVNLFKSHGYEHHGFTTEYDTSSQVRWMGVLNLEGKTPETLKKTFDSQR
Newman VPFEGREKNDALVNLFKSHGYEHHGFTTEYDTSSQVRWMGVLNLEGKTPETLKKTFDSQR
USA300_FPR3757 VPFEGREKNDALVNLFKSHGYEHHGFTTEYDTSSQVRWMGVLNLEGKTPETLKKTFDSQR
************************************************************
COL KRNINKAINYGVKVRFLERDEFNLFLDLYRETEERAGFVSKTDDYFYNFIDTYGDKVLVP
N315 KRNINKAINYGVKVRFLERDEFNLFLDLYRETEERAGFVSKTDDYFYNFIDTYGDKVLVP
NCTC8325 KRNINKAINYGVKVRFLERDEFNLFLDLYRETEERAGFVSKTDDYFYNFIDTYGDKVLVP
Newman KRNINKAINYGVKVRFLERDEFNLFLDLYRETEERAGFVSKTDDYFYNFIDTYGDKVLVP
USA300_FPR3757 KRNINKAINYGVKVRFLERDEFNLFLDLYRETEERAGFVSKTDDYFYNFIDTYGDKVLVP
************************************************************
COL LAYIDLDEYVLKLQQELNDKENRRDQMMAKENKSDKQMKKIAELDKQIDHDQHELLNASE
N315 LAYIDLDEYVLKLQQELNDKENRRDQMMAKENKSDKQMKKIAELDKQIDHDQHELLNASE
NCTC8325 LAYIDLDEYVLKLQQELNDKENRRDQMMAKENKSDKQMKKIAELDKQIDHDQHELLNASE
Newman LAYIDLDEYVLKLQQELNDKENRRDQMMAKENKSDKQMKKIAELDKQIDHDQHELLNASE
USA300_FPR3757 LAYIDLDEYVLKLQQELNDKENRRDQMMAKENKSDKQMKKIAELDKQIDHDQHELLNASE
************************************************************
COL LSKTDGPILNLASGVYFANAYEVNYFSGGSSEKYNQFMGPYMMHWFMINYCFDNGYDRYN
N315 LSKTDGPILNLASGVYFANAYEVNYFSGGSSEKYNQFMGPYMMHWFMINYCFDNGYDRYN
NCTC8325 LSKTDGPILNLASGVYFANAYEVNYFSGGSSEKYNQFMGPYMMHWFMINYCFDNGYDRYN
Newman LSKTDGPILNLASGVYFANAYEVNYFSGGSSEKYNQFMGPYMMHWFMINYCFDNGYDRYN
USA300_FPR3757 LSKTDGPILNLASGVYFANAYEVNYFSGGSSEKYNQFMGPYMMHWFMINYCFDNGYDRYN
************************************************************
COL FYGLSGDFTENSEDYGVYRFKRGFNVQIEELIGDFYKPIHKVKYWLFTTLDKLRKKLKK
N315 FYGLSGDFTENSEDYGVYRFKRGFNVQIEELIGDFYKPIHKVKYWLFTTLDKLRKKLKK
NCTC8325 FYGLSGDFTENSEDYGVYRFKRGFNVQIEELIGDFYKPIHKVKYWLFTTLDKLRKKLKK
Newman FYGLSGDFTENSEDYGVYRFKRGFNVQIEELIGDFYKPIHKVKYWLFTTLDKLRKKLKK
USA300_FPR3757 FYGLSGDFTENSEDYGVYRFKRGFNVQIEELIGDFYKPIHKVKYWLFTTLDKLRKKLKK
***********************************************************
- ↑ Stephanie Willing, Emma Dyer, Olaf Schneewind, Dominique Missiakas
FmhA and FmhC of Staphylococcus aureus incorporate serine residues into peptidoglycan cross-bridges.
J Biol Chem: 2020, 295(39);13664-13676
[PubMed:32759309] [WorldCat.org] [DOI] (I p)Anjini Gayatri Akkiraju, Krishnam Raju Atcha, Someswar Rao Sagurthi
Cloning, Purification, and Biophysical Characterization of FemB Protein from Methicillin-Resistant Staphylococcus aureus and Inhibitors Screening.
Appl Biochem Biotechnol: 2024, 196(8);4974-4992
[PubMed:37991634] [WorldCat.org] [DOI] (I p)