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⊟Summary[edit | edit source]
- pan ID?: SAUPAN003072000
- symbol?: —
- synonym:
- description?: TVP38/TMEM64 family protein
- TVP38/TMEM64 family protein
- alkaline phosphatase
- probable membrane protein
descriptions from strain specific annotations:
- strand?: +
- coordinates?: 3459082..3459657
- synteny block?: BlockID0021800
- occurrence?: in 100% of 34 strains
unnamed undecaprenyl-phosphate translocase [1]
Staphylococci have three systems to recycle undecaprenyl-phosphate from the extracellular leaflet of the membrane to the cytoplasm-facing leaflet. After dephosphorylation from undecaprenyl-pyrophosphate to undecaprenyl-phosphate, either polyprenyl-phosphate translocase or undecaprenyl-phosphate translocase can recycle UndP to the inner leaflet. This DedA-like translocase represents a third undecaprenyl-phosphate recycling system - it does contribute to UndP turnover but remains unnamed and is less well-characterized than the other two.
⊟Orthologs[edit | edit source]
04-02981:
SA2981_0918
08BA02176:
C248_0964
11819-97:
MS7_0918
6850:
RSAU_000840
71193:
ST398NM01_0946
ECT-R 2:
ECTR2_819
ED133:
SAOV_0910
ED98:
SAAV_0924
HO 5096 0412:
SAEMRSA15_07930
JH1:
SaurJH1_0982
JH9:
SaurJH9_0963
JKD6008:
SAA6008_00916
JKD6159:
SAA6159_00822
JSNZ:
JSNZ_000926
LGA251:
SARLGA251_08810
M013:
M013TW_0882
MRSA252:
SAR0925
MSHR1132:
SAMSHR1132_08150
MSSA476:
SAS0833
Mu3:
SAHV_0958
Mu50:
SAV0963
MW2:
MW0845
RF122:
SAB0832
ST398:
SAPIG0946
T0131:
SAT0131_00996 (thiD)
TCH60:
HMPREF0772_12283
TW20:
SATW20_09630
USA300_TCH1516:
USA300HOU_0922
VC40:
SAVC_03990
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGL
N315 MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGL
NCTC8325 MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGL
Newman MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGL
USA300_FPR3757 MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGL
************************************************************
COL ISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINF
N315 ISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINF
NCTC8325 ISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINF
Newman ISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINF
USA300_FPR3757 ISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINF
************************************************************
COL VASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLVVFWIVGKK
N315 VASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLVVFWIVGKK
NCTC8325 VASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLVVFWIVGKK
Newman VASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLVVFWIVGKK
USA300_FPR3757 VASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLVVFWIVGKK
************************************************************
COL LEQHFMGSKKE
N315 LEQHFMGSKKE
NCTC8325 LEQHFMGSKKE
Newman LEQHFMGSKKE
USA300_FPR3757 LEQHFMGSKKE
***********
- ↑ Brandon Sit, Veerasak Srisuknimit, Emilio Bueno, Franz G Zingl, Karthik Hullahalli, Felipe Cava, Matthew K Waldor
Undecaprenyl phosphate translocases confer conditional microbial fitness.
Nature: 2023, 613(7945);721-728
[PubMed:36450355] [WorldCat.org] [DOI] (I p)Ian J Roney, David Z Rudner
Two broadly conserved families of polyprenyl-phosphate transporters.
Nature: 2023, 613(7945);729-734
[PubMed:36450357] [WorldCat.org] [DOI] (I p)Anne Galinier, Clémentine Delan-Forino, Elodie Foulquier, Hakima Lakhal, Frédérique Pompeo
Recent Advances in Peptidoglycan Synthesis and Regulation in Bacteria.
Biomolecules: 2023, 13(5);
[PubMed:37238589] [WorldCat.org] [DOI] (I e)