Jump to navigation
Jump to search
⊟Summary[edit | edit source]
- pan ID?: SAUPAN002893000
- symbol?: —
- synonym:
- description?: DUF368 domain-containing protein
- DUF368 domain-containing protein
- putative DUF368-containing protein
- integral membrane protein
- Membrane protein
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 3338267..3339118
- synteny block?: BlockID0020590
- occurrence?: in 100% of 34 strains
popT : polyprenyl-phosphate translocase [1]
Staphylococci have three systems to recycle undecaprenyl-phosphate from the extracellular leaflet of the membrane to the cytoplasm-facing leaflet. After dephosphorylation from undecaprenyl-pyrophosphate to undecaprenyl-phosphate, either polyprenyl-phosphate translocase or undecaprenyl-phosphate translocase can recycle UndP to the inner leaflet. While the relative roles of each system are not fully elucidated, PopT appears to work under alkaline conditions to provide UndP recycling in the absence of a proton motive force. The third undecaprenyl-phosphate recycling system does contribute to UndP turnover but remains unnamed and is less well-characterized than the other two.
⊟Orthologs[edit | edit source]
04-02981:
SA2981_0796
08BA02176:
C248_0910
11819-97:
MS7_0868
6850:
RSAU_000791
71193:
ST398NM01_0896
ECT-R 2:
ECTR2_768
ED133:
SAOV_0858c
ED98:
SAAV_0812
HO 5096 0412:
SAEMRSA15_07430
JH1:
SaurJH1_0858
JH9:
SaurJH9_0842
JKD6008:
SAA6008_00863
JKD6159:
SAA6159_00772
JSNZ:
JSNZ_000800
LGA251:
SARLGA251_07700
M013:
M013TW_0833
MRSA252:
SAR0875
MSHR1132:
SAMSHR1132_07650
MSSA476:
SAS0783
Mu3:
SAHV_0837
Mu50:
SAV0841
MW2:
MW0794
RF122:
SAB0773c
ST398:
SAPIG0896
T0131:
SAT0131_00940
TCH60:
HMPREF0772_12335
TW20:
SATW20_09130
USA300_TCH1516:
USA300HOU_0869
VC40:
SAVC_03740
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIP
N315 MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIP
NCTC8325 MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIP
Newman MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIP
USA300_FPR3757 MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIP
************************************************************
COL IIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMV
N315 IIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMV
NCTC8325 IIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMV
Newman IIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMV
USA300_FPR3757 IIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMV
************************************************************
COL IAGIAILIVITLMNNGDKHAGETLTLSTSLIIKYFIAGMCASSAMLLPGISGSFMLLVFG
N315 IAGIAILIVITLMNNGDKHAGETLTLSTGLIIKYFIAGMCASSAMLLPGISGSFMLLVFG
NCTC8325 IAGIAILIVITLMNNGDKHAGETLTLSTSLIIKYFIAGMCASSAMLLPGISGSFMLLVFG
Newman IAGIAILIVITLMNNGDKHAGETLTLSTSLIIKYFIAGMCASSAMLLPGISGSFMLLVFG
USA300_FPR3757 IAGIAILIVITLMNNGDKHAGETLTLSTSLIIKYFIAGMCASSAMLLPGISGSFMLLVFG
****************************.*******************************
COL VYGTVMLAISEVVKLNFAGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFV
N315 VYGTVMLAISEVVKLNFTGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFV
NCTC8325 VYGTVMLAISEVVKLNFAGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFV
Newman VYGTVMLAISEVVKLNFAGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFV
USA300_FPR3757 VYGTVMLAISEVVKLNFAGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFV
*****************:******************************************
COL VGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
N315 VGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
NCTC8325 VGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
Newman VGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
USA300_FPR3757 VGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
*******************************************
- ↑ Brandon Sit, Veerasak Srisuknimit, Emilio Bueno, Franz G Zingl, Karthik Hullahalli, Felipe Cava, Matthew K Waldor
Undecaprenyl phosphate translocases confer conditional microbial fitness.
Nature: 2023, 613(7945);721-728
[PubMed:36450355] [WorldCat.org] [DOI] (I p)Ian J Roney, David Z Rudner
Two broadly conserved families of polyprenyl-phosphate transporters.
Nature: 2023, 613(7945);729-734
[PubMed:36450357] [WorldCat.org] [DOI] (I p)Anne Galinier, Clémentine Delan-Forino, Elodie Foulquier, Hakima Lakhal, Frédérique Pompeo
Recent Advances in Peptidoglycan Synthesis and Regulation in Bacteria.
Biomolecules: 2023, 13(5);
[PubMed:37238589] [WorldCat.org] [DOI] (I e)