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⊟Summary[edit | edit source]
- pan ID?: SAUPAN002623000
- symbol?: dtpT
- synonym:
- description?: MFS transporter
- MFS transporter
- peptide MFS transporter
- amino acid/peptide transporter (peptide:H+ symporter)
- di-/tripeptide ABC transporter
- dipeptide/tripeptide:H symporter, putative
- proton-dependent oligopeptide transporter family protein
- amino acid/peptide transporter
- Di/tripeptide permease YjdL
- putative proton-dependent oligopeptide transportprotein
- amino acid/peptide transporter (Peptide:H+ symporter) family protein
- di-/tripeptide transporter
- di-tripeptide ABC transporter
- H+ symporter family protein
- POT family proton (H+)-dependent oligopeptide transporter
- proton-dependent oligopeptide transport protein
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 3128836..3130341
- synteny block?: BlockID0018580
- occurrence?: in 100% of 34 strains
dtpT : dipeptide and tripeptide:proton symporter [1] [2]
Staphylococci are able to take up short polymers of two or three amino acids from the environment for nutrition via the DtpT proton motive force-driven transporter. Larger oligopeptides (3-8 residue polymers) require transport by the opp3 oligopeptide permease system. DtpT is also able to contribute to transport of host glutathione and shows preferences for peptides containing aspartate or glutamate residues and against transporting peptides containing glutamine or tyrosine residues.
⊟Orthologs[edit | edit source]
04-02981:
SA2981_0705 (yjdL)
08BA02176:
C248_0814
11819-97:
MS7_0778
6850:
RSAU_000702
71193:
ST398NM01_0804
ECT-R 2:
ECTR2_677
ED133:
SAOV_0762c
ED98:
SAAV_0688
HO 5096 0412:
SAEMRSA15_06530
JH1:
SaurJH1_0767
JH9:
SaurJH9_0750
JKD6008:
SAA6008_00742
JKD6159:
SAA6159_00682
JSNZ:
JSNZ_000696
LGA251:
SARLGA251_06600
M013:
M013TW_0713
MRSA252:
SAR0781
MSHR1132:
SAMSHR1132_06720
MSSA476:
SAS0692
Mu3:
SAHV_0724
Mu50:
SAV0727
MW2:
MW0689
RF122:
SAB0676c
ST398:
SAPIG0804
T0131:
SAT0131_00797
TCH60:
HMPREF0772_12459
TW20:
SATW20_08020
USA300_TCH1516:
USA300HOU_0751
VC40:
SAVC_03270
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MTQQNSHGNQIQDIPQTGFFGHPRGLGVLFFVEFWERFSYYGMRALLIFYMYFAVTDNGL
N315 MTQQNSHGNQIQDIPQTGFFGHPRGLGVLFFVEFWERFSYYGMRALLIFYMYFAVTDNGL
NCTC8325 MTQQNSHGNQIQDIPQTGFFGHPRGLGVLFFVEFWERFSYYGMRALLIFYMYFAVTDNGL
Newman MTQQNSHGNQIQDIPQTGFFGHPRGLGVLFFVEFWERFSYYGMRALLIFYMYFAVTDNGL
USA300_FPR3757 MTQQNSHGNQIQDIPQTGFFGHPRGLGVLFFVEFWERFSYYGMRALLIFYMYFAVTDNGL
************************************************************
COL GIDKTTAMSIMSVYGSLIYMTSIPGGWIADRITGTRGATLLGAVFIIIGHICLSLPFALI
N315 GIDKTTAMSIMSVYGSLIYMTSIPGGWIADRITGTRGATLLGAVFIIIGHICLSLPFALI
NCTC8325 GIDKTTAMSIMSVYGSLIYMTSIPGGWIADRITGTRGATLLGAVFIIIGHICLSLPFALI
Newman GIDKTTAMSIMSVYGSLIYMTSIPGGWIADRITGTRGATLLGAVFIIIGHICLSLPFALI
USA300_FPR3757 GIDKTTAMSIMSVYGSLIYMTSIPGGWIADRITGTRGATLLGAVFIIIGHICLSLPFALI
************************************************************
COL GLFTSMFFIIIGSGLMKPNISNIVGRLYPENDRRMDAGFVIFYMSVNMGALLSPIILQHF
N315 GLFTSMFFIIIGSGLMKPNISNIVGRLYPENDRRMDAGFVIFYMSVNMGALLSPIILQHF
NCTC8325 GLFTSMFFIIIGSGLMKPNISNIVGRLYPENDRRMDAGFVIFYMSVNMGALLSPIILQHF
Newman GLFTSMFFIIIGSGLMKPNISNIVGRLYPENDRRMDAGFVIFYMSVNMGALLSPIILQHF
USA300_FPR3757 GLFTSMFFIIIGSGLMKPNISNIVGRLYPENDRRMDAGFVIFYMSVNMGALLSPIILQHF
************************************************************
COL VNVKNFHGGFLIAAVGMALGLVWYVLFNRKNLGSVGMKPTNPLTPAEKKKYGLIIGSVVL
N315 VNVKNFHGGFLIAAVGMALGLVWYVLFNRKNLGSVGMKPTNPLTPAEKKKYGLIIGSVVL
NCTC8325 VNVKNFHGGFLIAAVGMALGLVWYVLFNRKNLGSVGMKPTNPLTPAEKKKYGLIIGSVVL
Newman VNVKNFHGGFLIAAVGMALGLVWYVLFNRKNLGSVGMKPTNPLTPAEKKKYGLIIGSVVL
USA300_FPR3757 VNVKNFHGGFLIAAVGMALGLVWYVLFNRKNLGSVGMKPTNPLTPAEKKKYGLIIGSVVL
************************************************************
COL AIVLIIVIGALTNSLSFNLVSNTVLVLGIALPIIYFTLIIRSKDVTDTERSRVKAFIPLF
N315 AIVLIIVIGALTNSLSFNLVSNTVLVLGIALPIIYFTLIIRSKDVTDTERSRVKAFIPLF
NCTC8325 AIVLIIVIGALTNSLSFNLVSNTVLVLGIALPIIYFTLIIRSKDVTDTERSRVKAFIPLF
Newman AIVLIIVIGALTNSLSFNLVSNTVLVLGIALPIIYFTLIIRSKDVTDTERSRVKAFIPLF
USA300_FPR3757 AIVLIIVIGALTNSLSFNLVSNTVLVLGIALPIIYFTLIIRSKDVTDTERSRVKAFIPLF
************************************************************
COL ILGMVFWAIQEQGSNVLNIYGIEHSDMKLNLFGWKTNFGEAIFQSINPLFILLLAPIISL
N315 ILGMVFWAIQEQGSNVLNIYGIEHSDMKLNLFGWKTNFGEAIFQSINPLFILLLAPIISL
NCTC8325 ILGMVFWAIQEQGSNVLNIYGIEHSDMKLNLFGWKTNFGEAIFQSINPLFILLLAPIISL
Newman ILGMVFWAIQEQGSNVLNIYGIEHSDMKLNLFGWKTNFGEAIFQSINPLFILLLAPIISL
USA300_FPR3757 ILGMVFWAIQEQGSNVLNIYGIEHSDMKLNLFGWKTNFGEAIFQSINPLFILLLAPIISL
************************************************************
COL LWQKLGTKQPSLPVKFAIGTFLAGASYILIGIVGYASGSSNFSVNWVILSYIICVIGELC
N315 LWQKLGTKQPSLPVKFAIGTFLAGASYILIGIVGYASGSSNFSVNWVILSYIICVIGELC
NCTC8325 LWQKLGTKQPSLPVKFAIGTFLAGASYILIGIVGYASGSSNFSVNWVILSYIICVIGELC
Newman LWQKLGTKQPSLPVKFAIGTFLAGASYILIGIVGYASGSSNFSVNWVILSYIICVIGELC
USA300_FPR3757 LWQKLGTKQPSLPVKFAIGTFLAGASYILIGIVGYASGSSNFSVNWVILSYIICVIGELC
************************************************************
COL LSPTGNSAAVKLAPKAFNAQMMSIWYLTNASAQAINGTLVKLIEPLGQTNYFIFLGVVAI
N315 LSPTGNSAAVKLAPKAFNAQMMSIWYLTNASAQAINGTLVKLIEPLGQTNYFIFLGVVAI
NCTC8325 LSPTGNSAAVKLAPKAFNAQMMSIWYLTNASAQAINGTLVKLIEPLGQTNYFIFLGVVAI
Newman LSPTGNSAAVKLAPKAFNAQMMSIWYLTNASAQAINGTLVKLIEPLGQTNYFIFLGVVAI
USA300_FPR3757 LSPTGNSAAVKLAPKAFNAQMMSIWYLTNASAQAINGTLVKLIEPLGQTNYFIFLGVVAI
************************************************************
COL IVTTIVLAFSPLIIKAMKGIR
N315 IVTTIVLAFSPLIIKAMKGIR
NCTC8325 IVTTIVLAFSPLIIKAMKGIR
Newman IVTTIVLAFSPLIIKAMKGIR
USA300_FPR3757 IVTTIVLAISPLIIKAMKGIR
********:************
- ↑ Aurelia Hiron, Elise Borezée-Durant, Jean-Christophe Piard, Vincent Juillard
Only one of four oligopeptide transport systems mediates nitrogen nutrition in Staphylococcus aureus.
J Bacteriol: 2007, 189(14);5119-29
[PubMed:17496096] [WorldCat.org] [DOI] (P p)