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NCBI: 03-AUG-2016

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus NCTC8325
  • locus tag: SAOUHSC_01221
  • pan locus tag?: SAUPAN003545000
  • symbol: SAOUHSC_01221
  • pan gene symbol?: dprA
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SAOUHSC_01221
  • symbol: SAOUHSC_01221
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1171904..1172644
  • length: 741
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    GTGAATAGGGAAGAAAATGTTCATTTATTACGTAAATACTATGCTTTTATAAAACTTGAT
    CATAACGATATTATTAAAGAACTGCAGAAATTAAAAGTAAGTTACATTACATATATGGAT
    TCTGAATACCCAGTGCTATTAAAAGAAATATATCAATTTCCATTACTTCTTTTCTATAAA
    GGGAACATCAAATTAATAAATAATATGCATCATTTGGCAGTAGTAGGTGCAAGAGATTCT
    ACAAGTTATACCCAACAGTCTTTAGAATTTTTATTATCAAATGATAAAAGCAAATATTTA
    ACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAAATAGCTTTAAAA
    TACAATCTCCCTACAATTGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAAAGT
    ACATTAGCATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCTGAATATCCACCA
    CATACACCAATCGCTAAATATAGATTTCCTGAGCGCAATAGAATTATCAGCGGTTTGTCA
    AAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTGGCAGTCACATCACGATAGATTTT
    GCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTTAATCCTATGACA
    AAAGGTAATTTATTACGTATCCAAGAAGGTGCTAAGGTAGTATTAAACGCTAATGATATA
    TTTGAAGACTACTATATTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    741

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SAOUHSC_01221
  • symbol: SAOUHSC_01221
  • description: hypothetical protein
  • length: 246
  • theoretical pI: 9.36378
  • theoretical MW: 28166.4
  • GRAVY: -0.20813

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes DNA transformation DNA protecting protein DprA (TIGR00732; HMM-score: 220.1)
  • TheSEED  :
    • Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake
    RNA Metabolism RNA processing and modification YrdC-YciO-Sua5 and associated protein families  Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake
  • PFAM:
    DprA (CL0349) DNA_processg_A; DNA recombination-mediator protein A (PF02481; HMM-score: 235.6)
    and 2 more
    MoCo_carrier; Putative molybdenum carrier (PF12694; HMM-score: 19.5)
    no clan defined DUF2493; Protein of unknown function (DUF2493) (PF10686; HMM-score: 13.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.32
    • Cytoplasmic Membrane Score: 9.55
    • Cellwall Score: 0.12
    • Extracellular Score: 0.01
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001236
    • TAT(Tat/SPI): 0.000085
    • LIPO(Sec/SPII): 0.000228
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MNREENVHLLRKYYAFIKLDHNDIIKELQKLKVSYITYMDSEYPVLLKEIYQFPLLLFYKGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQIALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHITIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
    Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
    PLoS Genet: 2016, 12(4);e1005962
    [PubMed:27035918] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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