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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL1266 [new locus tag: SACOL_RS06465 ]
  • pan locus tag?: SAUPAN003545000
  • symbol: SACOL1266
  • pan gene symbol?: dprA
  • synonym:
  • product: DNA processing protein DprA

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL1266 [new locus tag: SACOL_RS06465 ]
  • symbol: SACOL1266
  • product: DNA processing protein DprA
  • replicon: chromosome
  • strand: +
  • coordinates: 1275538..1276410
  • length: 873
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    TTGATTAAACTATTTTTGCTTAAGTTATACTGGGCACACTTTTCGACTAAACAAATTCAT
    CAATTTTTAATGGCATATCCTAATGTAATTAAAGAGGAGGGAAGAAAAAAAGATAGTTAT
    TTATGTGAATGGGTGAATAGGGAAGAAAATGTTCATTTATTACGTAAATACTATGCTTTT
    ATAAAACTTGATCATAACGATATTATTAAAGAACTGCAGAAATTAAAAGTAAGTTACATT
    ACATATATGGATTCTGAATACCCAGTGCTATTAAAAGAAATATATCAATTTCCATTACTT
    CTTTTCTATAAAGGGAACATCAAATTAATAAATAATATGCATCATTTGGCAGTAGTAGGT
    GCAAGAGATTCTACAAGTTATACCCAACAGTCTTTAGAATTTTTATTATCAAATGATAAA
    AGCAAATATTTAACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
    ATAGCTTTAAAATACAATCTCCCTACAATTGCAGTTTTAGCCTTTGGCCATCAAACACAT
    TATCCCAAAAGTACATTAGCATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCT
    GAATATCCACCACATACACCAATCGCTAAATATAGATTTCCTGAGCGCAATAGAATTATC
    AGCGGTTTGTCAAAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTGGCAGTCACATC
    ACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTT
    AATCCTATGACAAAAGGTAATTTATTACGTATCCAAGAAGGTGCTAAGGTAGTATTAAAC
    GCTAATGATATATTTGAAGACTACTATATTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    873

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL1266 [new locus tag: SACOL_RS06465 ]
  • symbol: SACOL1266
  • description: DNA processing protein DprA
  • length: 290
  • theoretical pI: 9.51915
  • theoretical MW: 33564.7
  • GRAVY: -0.203103

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes DNA transformation DNA protecting protein DprA (TIGR00732; HMM-score: 219.3)
  • TheSEED  :
    • Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake
    RNA Metabolism RNA processing and modification YrdC-YciO-Sua5 and associated protein families  Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake
  • PFAM:
    DprA (CL0349) DNA_processg_A; DNA recombination-mediator protein A (PF02481; HMM-score: 234.9)
    and 2 more
    MoCo_carrier; Putative molybdenum carrier (PF12694; HMM-score: 19.2)
    no clan defined DUF2493; Protein of unknown function (DUF2493) (PF10686; HMM-score: 12.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.32
    • Cytoplasmic Membrane Score: 9.55
    • Cellwall Score: 0.12
    • Extracellular Score: 0.01
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.021886
    • TAT(Tat/SPI): 0.000925
    • LIPO(Sec/SPII): 0.007845
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MIKLFLLKLYWAHFSTKQIHQFLMAYPNVIKEEGRKKDSYLCEWVNREENVHLLRKYYAFIKLDHNDIIKELQKLKVSYITYMDSEYPVLLKEIYQFPLLLFYKGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQIALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHITIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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