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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS14185 [old locus tag: SACOL2712 ]
  • pan locus tag?: SAUPAN006445000
  • symbol: SACOL_RS14185
  • pan gene symbol?: drp35
  • synonym:
  • product: lactonase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS14185 [old locus tag: SACOL2712 ]
  • symbol: SACOL_RS14185
  • product: lactonase
  • replicon: chromosome
  • strand: -
  • coordinates: 2784346..2785317
  • length: 972
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002951 (2784346..2785317) NCBI
  • BioCyc: SACOL_RS14185 BioCyc
  • MicrobesOnline: see SACOL2712

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGTCACAACAAGATTTACCTACATTATTTTATAGCGGGAAGTCCAATAGTGCTGTTCCA
    ATTATATCTGAAAGTGAATTACAAACAATTACAGCTGAACCATGGCTTGAAATTTCCAAA
    AAAGGATTGCAACTAGAAGGATTGAACTTTGATCGGCAGGGACAACTCTTTTTATTGGAT
    GTATTCGAAGGCAATATTTTCAAAATCAATCCTGAAACGAAGGAAATCAAACGACCTTTT
    GTAAGTCACAAAGCGAATCCTGCAGCAATCAAAATACATAAAGATGGCCGATTATTCGTT
    TGTTATTTAGGAGATTTTAAATCTACAGGAGGCATTTTTGCAGCTACAGAAAATGGTGAC
    AACTTACAAGATATTATTGAAGATCTTTCAACAGCATATTGTATTGATGACATGGTATTT
    GATTCTAAAGGTGGATTTTATTTTACAGATTTTAGAGGATACTCTACCAATCCACTAGGA
    GGCGTTTATTATGTTTCGCCGGACTTTAGAACAGTGACGCCTATCATTCAAAATATTAGC
    GTAGCAAATGGTATTGCTTTAAGTACAGATGAAAAAGTACTATGGGTAACAGAAACAACA
    GCCAATCGATTACATCGCATTGCACTTGAAGATGATGGTGTGACGATACAACCATTTGGA
    GCTACCATACCGTACTATTTTACAGGTCATGAAGGACCAGACTCATGTTGTATTGATAGT
    GACGATAATTTATACGTAGCAATGTATGGTCAAGGTCGAGTGTTAGTTTTTAATAAAAGG
    GGTTATCCAATAGGACAAATATTGATACCAGGCCGAGATGAAGGGCATATGTTACGTTCT
    ACTCATCCGCAATTTATACCTGGAACAAATCAACTCATCATTTGTTCCAATGATATAGAA
    ATGGGCGGAGGGTCTATGCTTTATACAGTTAATGGCTTTGCAAAAGGTCATCAAAGTTTT
    CAGTTTCAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    972

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL_RS14185 [old locus tag: SACOL2712 ]
  • symbol: SACOL_RS14185
  • description: lactonase
  • length: 323
  • theoretical pI: 4.71521
  • theoretical MW: 35832.2
  • GRAVY: -0.19257

⊟Function[edit | edit source]

  • reaction:
    EC 3.1.1.-?  ExPASy
  • TIGRFAM:
  • TheSEED: see SACOL2712
  • PFAM:
    Beta_propeller (CL0186) SGL; SMP-30/Gluconolaconase/LRE-like region (PF08450; HMM-score: 102.2)
    and 3 more
    Arylesterase; Arylesterase (PF01731; HMM-score: 28.9)
    Str_synth; Strictosidine synthase (PF03088; HMM-score: 27.7)
    NHL; NHL repeat (PF01436; HMM-score: 23)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors: Ca2+
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 10
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003495
    • TAT(Tat/SPI): 0.000154
    • LIPO(Sec/SPII): 0.000415
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSQQDLPTLFYSGKSNSAVPIISESELQTITAEPWLEISKKGLQLEGLNFDRQGQLFLLDVFEGNIFKINPETKEIKRPFVSHKANPAAIKIHKDGRLFVCYLGDFKSTGGIFAATENGDNLQDIIEDLSTAYCIDDMVFDSKGGFYFTDFRGYSTNPLGGVYYVSPDFRTVTPIIQNISVANGIALSTDEKVLWVTETTANRLHRIALEDDGVTIQPFGATIPYYFTGHEGPDSCCIDSDDNLYVAMYGQGRVLVFNKRGYPIGQILIPGRDEGHMLRSTHPQFIPGTNQLIICSNDIEMGGGSMLYTVNGFAKGHQSFQFQ

⊟Experimental data[edit | edit source]

  • experimentally validated: see SACOL2712
  • protein localization: see SACOL2712
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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