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NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus COL
- locus tag: SACOL_RS12040 [old locus tag: SACOL2290 ]
- pan locus tag?: SAUPAN005764000
- symbol: SACOL_RS12040
- pan gene symbol?: —
- synonym:
- product: AraC family transcriptional regulator
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SACOL_RS12040 [old locus tag: SACOL2290 ]
- symbol: SACOL_RS12040
- product: AraC family transcriptional regulator
- replicon: chromosome
- strand: -
- coordinates: 2348767..2350722
- length: 1956
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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1921ATGACAGATAATTATTCACTACATATTTATAAAAGTATGAAAATGAGTAGTGTGAAGGAA
GCGAACTTAAAAATTATATATTGGCTACAAGGTACAGGTGTAGTTTCAATCAATCTACAA
CAATATGATGTAAAAAGAAATGATGTCACCATTATTATGTTGAATGATTTGTATCAAATT
GATGGTAATGATGATAGTGTATGTTGTGTTGTTGAAGTAAGTGCAAAGACATTTTTGAAG
TTTATGAATGCAAACTATATGATGCGTGGCAAGATATTAACAAATGAGGTTGCTAGCACT
TTTAGAATCTTGATTAAGTATTTAATCTACAGCAAAATTAAACAACAGTCTTATAATGCT
AATGATAAGATTATTAATTACATGTGTGTTGAATTAATGTCATTAAATACATACGATGGT
AGTCGTCATTTAGTAGCCGAAGAAGTGCACGATTATTTAACAAACAACCACCATAAAAAG
ATAAATAGGAAAGATGTCATTAATCAAGTTAGTATTACAAACAAAGCTTTAAGTGACATG
TTTAAAGCGACACCTTATAGTAATTTTATTCAATATTTAAATCATATTAGACTGGAGCAT
TGCTTAATTGATATTTTAACTTCTAAGAAGCCTATTGAAGAAATCGCAAGTAGTCATGGT
TTTAATCATTATTCTCGTTTTATACACCTCTTTAAAGAAACGTATGGTAACACTCCTAAA
TTAATTAGAAAAAGATATAGTCCAACATCTCATTCAATTAACCATTCCCAATTAGTTGAA
ATTGATAAAAATATAATTGAATTATTTGATGATACTAATCAAAGTTCTTCAAGTATGCGC
GAGATTGATATACCTTTTGAGCCTACAAAAAGGAGTCAAATGTATCAACCTAAAAACATT
TATATTAAAGGAAGTAATTTTTATTGGATGGATTATTATACTATTAAACAAATCATTCAA
AGATTAGGTGTTAATCCTGAAAACTTGCATATAATTGTTACAATCGACACAAGCAATGAG
CTATCGATTGAACAAATCACTTTATTACTTCAAAAGATAGTGAATTACAATGTAAATGTA
GTGTTTCGTATTAAACATGAATATAAGGAATTGTTAACGAGTGCTGAAAGAGGCAAGATA
GAAAAGCTAGTAGCTACAATTTTTAATATGACTTTTGAGAGTAATAGATGTAAGATTGCA
TTTTTAATTAACGACTTAAATACTACTGCAATTCAAAAACTGAAACGTTTAATAGATAAT
TATATAGGAGTATTTGAATTAATATATCATCTGGAACCAAAAGAGTTGAATACGCGCTAT
GATAAAGAAATTGATCATCTAATAGACTATTTTATCTTACCGCTAAGACAAATAGAACAG
GTGTCTATTGCACGTTCTAAAATTATATGTGATGTAGATTTGATTAATGAGAATAATGAC
TTAAAAGAAAAAATCACAATGTCTGATATTAATAAGGTTTCTGAACTTTTGACAAATTAT
ACAAAATTTCGAGGACTTATTATGCACATGTCAATTATAAGTGAATCGAGCAAAGAAATA
AATTTAACTAGATTATCAATATTCATTTTTATCATAAATATACTTAATCAATTACGAGGG
ATTGTTATTTATCAAAATGACACGATGATTGTAACGAAGTTCAAACATGAAGTACAATGT
GTCATTTGTTTGCCAGCCGCATTGTTAAATGAGAATTCAGACGCTATACGTTTATCGTGT
AAGGGTCTTCAACAATTTAGCCATGCTAAAACTAAACAAATTGTTTTAAGTATAGATAAA
GATAATCATACTTCCGAAAATGGTGTACTTGTGAATGATATTATGCAACAACACAGTTAT
TGGAAAGCTAATTTTATAGAAAGAAATATTTATGATCATTCATTAATGGTCTCAAGCAAT
AGTATTGTTCATTTGAAATATCATCTTGAGATATAG60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SACOL_RS12040 [old locus tag: SACOL2290 ]
- symbol: SACOL_RS12040
- description: AraC family transcriptional regulator
- length: 651
- theoretical pI: 8.28527
- theoretical MW: 76005.3
- GRAVY: -0.224578
⊟Function[edit | edit source]
- TIGRFAM: YSIRK-targeted surface antigen transcriptional regulator (TIGR04094; HMM-score: 38.1)
- TheSEED: see SACOL2290
- PFAM: HTH (CL0123) HTH_18; Helix-turn-helix domain (PF12833; HMM-score: 54.6)and 1 moreHTH_AraC; Bacterial regulatory helix-turn-helix proteins, AraC family (PF00165; HMM-score: 30.3)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 2.5
- Cytoplasmic Membrane Score: 2.5
- Cellwall Score: 2.5
- Extracellular Score: 2.5
- Internal Helices: 0
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.019049
- TAT(Tat/SPI): 0.00021
- LIPO(Sec/SPII): 0.000901
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MTDNYSLHIYKSMKMSSVKEANLKIIYWLQGTGVVSINLQQYDVKRNDVTIIMLNDLYQIDGNDDSVCCVVEVSAKTFLKFMNANYMMRGKILTNEVASTFRILIKYLIYSKIKQQSYNANDKIINYMCVELMSLNTYDGSRHLVAEEVHDYLTNNHHKKINRKDVINQVSITNKALSDMFKATPYSNFIQYLNHIRLEHCLIDILTSKKPIEEIASSHGFNHYSRFIHLFKETYGNTPKLIRKRYSPTSHSINHSQLVEIDKNIIELFDDTNQSSSSMREIDIPFEPTKRSQMYQPKNIYIKGSNFYWMDYYTIKQIIQRLGVNPENLHIIVTIDTSNELSIEQITLLLQKIVNYNVNVVFRIKHEYKELLTSAERGKIEKLVATIFNMTFESNRCKIAFLINDLNTTAIQKLKRLIDNYIGVFELIYHLEPKELNTRYDKEIDHLIDYFILPLRQIEQVSIARSKIICDVDLINENNDLKEKITMSDINKVSELLTNYTKFRGLIMHMSIISESSKEINLTRLSIFIFIINILNQLRGIVIYQNDTMIVTKFKHEVQCVICLPAALLNENSDAIRLSCKGLQQFSHAKTKQIVLSIDKDNHTSENGVLVNDIMQQHSYWKANFIERNIYDHSLMVSSNSIVHLKYHLEI
⊟Experimental data[edit | edit source]
- experimentally validated:
- protein localization: see SACOL2290
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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