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NCBI: 10-JUN-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus COL
- locus tag: SACOL2271 [new locus tag: SACOL_RS11940 ]
- pan locus tag?: SAUPAN005739000
- symbol: modB
- pan gene symbol?: modB
- synonym:
- product: molybdenum ABC transporter permease ModB
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SACOL2271 [new locus tag: SACOL_RS11940 ]
- symbol: modB
- product: molybdenum ABC transporter permease ModB
- replicon: chromosome
- strand: -
- coordinates: 2332355..2333026
- length: 672
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 3237402 NCBI
- RefSeq: YP_187078 NCBI
- BioCyc: see SACOL_RS11940
- MicrobesOnline: 913753 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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661ATGCCTGACTTAACACCTTTTTGGATATCAATACGAGTTGCTGTAATCAGTACGATTATT
GTAACGGTTTTAGGTATTTTTATATCTAAATGGTTGTATCGTCGTAAGGGTTCGTGGGTT
AAAGTATTGGAAAGTTTATTGATATTACCTATTGTTTTGCCGCCAACGGTATTAGGTTTT
ATTCTATTAATCATCTTCTCGCCAAGAGGACCAATCGGTCAATTCTTTGCGAATGTACTA
CATTTACCTGTAGTGTTCACTTTGACAGGTGCTGTGATAGCATCTGTCATTGTTAGTTTT
CCACTAATGTATCAACATACTGTGCAAGGCTTCAGAGGTATAGACACGAAAATGATTAAT
ACAGCTAGAACGATGGGAGCAAGTGAAACGAAAATTTTCCTCAAATTAATTTTACCATTA
GCTAAACGCTCTATTTTAGCAGGTATAATGATGAGTTTTGCTCGTGCATTAGGTGAGTTT
GGTGCTACATTAATGGTTGCAGGATATATTCCAAATAAAACGAATACACTACCTTTAGAA
ATATACTTCTTAGTGGAACAAGGTAGAGAAAATGAAGCGTGGTTATGGGTATTAGTGCTA
GTCGCATTCTCTATTGTGGTTATATCTACAATTAATTTATTGAATAAAGATAAATATAAG
GAGGTCGACTAG60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SACOL2271 [new locus tag: SACOL_RS11940 ]
- symbol: ModB
- description: molybdenum ABC transporter permease ModB
- length: 223
- theoretical pI: 10.4601
- theoretical MW: 24862.8
- GRAVY: 0.799552
⊟Function[edit | edit source]
- TIGRFAM: Transport and binding proteins Anions molybdate ABC transporter, permease protein (TIGR02141; HMM-score: 260.9)and 11 moreNifC-like ABC-type porter (TIGR01581; HMM-score: 155.4)Transport and binding proteins Anions sulfate ABC transporter, permease protein (TIGR00969; HMM-score: 135.8)Transport and binding proteins Anions sulfate ABC transporter, permease protein CysT (TIGR02139; HMM-score: 123)Transport and binding proteins Anions sulfate ABC transporter, permease protein CysW (TIGR02140; HMM-score: 107.8)Transport and binding proteins Amino acids, peptides and amines putative 2-aminoethylphosphonate ABC transporter, permease protein (TIGR03262; HMM-score: 65.1)2-aminoethylphosphonate ABC transport system, membrane component PhnV (TIGR03255; HMM-score: 59.8)Transport and binding proteins Anions phosphate ABC transporter, permease protein PstC (TIGR02138; HMM-score: 51.7)Transport and binding proteins Anions phosphate ABC transporter, permease protein PstA (TIGR00974; HMM-score: 49.8)2-aminoethylphosphonate ABC transporter, permease protein (TIGR03226; HMM-score: 48.2)Transport and binding proteins Other thiamine/thiamine pyrophosphate ABC transporter, permease protein (TIGR01253; HMM-score: 29.7)choline ABC transporter, permease protein (TIGR03416; HMM-score: 12.3)
- TheSEED :
- Molybdenum ABC transporter (EC 7.3.2.5), permease protein ModB
- PFAM: BPD_transp_1 (CL0404) BPD_transp_1; Binding-protein-dependent transport system inner membrane component (PF00528; HMM-score: 68.4)and 2 moreno clan defined SieB; Super-infection exclusion protein B (PF14163; HMM-score: 9.7)VSA (CL0656) Stevor; Subtelomeric Variable Open Reading frame (PF17410; HMM-score: 9)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 4
- LocateP: Multi-transmembrane
- Prediction by SwissProt Classification: Membrane
- Pathway Prediction: Sec-(SPI)
- Intracellular possibility: 0.17
- Signal peptide possibility: -1
- N-terminally Anchored Score: -1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.001381
- TAT(Tat/SPI): 0.000153
- LIPO(Sec/SPII): 0.004647
- predicted transmembrane helices (TMHMM): 5
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MPDLTPFWISIRVAVISTIIVTVLGIFISKWLYRRKGSWVKVLESLLILPIVLPPTVLGFILLIIFSPRGPIGQFFANVLHLPVVFTLTGAVIASVIVSFPLMYQHTVQGFRGIDTKMINTARTMGASETKIFLKLILPLAKRSILAGIMMSFARALGEFGATLMVAGYIPNKTNTLPLEIYFLVEQGRENEAWLWVLVLVAFSIVVISTINLLNKDKYKEVD
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: modC < modB < modA
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
The Staphylococcus aureus proteome.
Int J Med Microbiol: 2014, 304(2);110-20
[PubMed:24439828] [WorldCat.org] [DOI] (I p)