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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL1538 [new locus tag: SACOL_RS07840 ]
  • pan locus tag?: SAUPAN004028000
  • symbol: scpA
  • pan gene symbol?: scpA
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL1538 [new locus tag: SACOL_RS07840 ]
  • symbol: scpA
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1576208..1576939
  • length: 732
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGTATGAAGTTAAATTAGATGCTTTCAATGGACCATTAGATTTATTGCTGCATCTTATC
    CAAAAATTTGAAATAGATATTTATGATATTCCTATGCAAGCATTAACAGAGCAGTATATG
    CAGTACGTTCATGCAATGAAACAGCTTGAAATTAATATTGCAAGTGAATACCTAGTATTA
    GCGTCAGAACTCTTAATGATTAAAAGTAAGATGCTATTACCACAATCAACATCAGATATG
    GATGTTGATGATGACCCACGGGAAGATTTAGTTGGGCGTTTAATAGAATATCAAAATTAT
    AAAGAATATACTGCTATTTTAAATGACATGAAAGAAGAAAGAGATTTTTATTTTACAAAA
    AGACCGACAGATTTATCTCATTTGGAAACAGATGAATCTTGGGATCCAAATCATACGATT
    GATTTAACTGAATTAATTGTAGCTTATCAAAGAGTTAAAAATAGAGTTGAGTTAAATACA
    CCTAAATCTGTTGAAATCCGAAAAGAGACATTTACCATTCAACAAGCTACAGAACAAGTG
    ACATCGAGATTGAAAGATAAAGATCATTTTAACTTCTTTAGTCTGTTTACGTTTTCTGAG
    CCAATTGAACAAGTAGTCACTCACTTTTTAGCTATTTTAGAGATGTCAAAAGCAGGAATA
    ATTAATATTGAGCAACAACGTAATTTTGAAGATATTAACATTATTAGAGGAGTGAACTAC
    CATTTTGGATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    732

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL1538 [new locus tag: SACOL_RS07840 ]
  • symbol: ScpA
  • description: hypothetical protein
  • length: 243
  • theoretical pI: 4.4679
  • theoretical MW: 28670.4
  • GRAVY: -0.373251

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • Segregation and condensation protein A
    Cell Division and Cell Cycle Cell Division and Cell Cycle - no subcategory Two cell division clusters relating to chromosome partitioning  Segregation and condensation protein A
  • PFAM:
    Kleisin (CL0157) SMC_ScpA; Segregation and condensation protein ScpA (PF02616; HMM-score: 121.9)
    and 2 more
    Rad21_Rec8; Conserved region of Rad21 / Rec8 like protein (PF04824; HMM-score: 14.9)
    no clan defined EB1; EB1-like C-terminal motif (PF03271; HMM-score: 12.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00226
    • TAT(Tat/SPI): 0.000067
    • LIPO(Sec/SPII): 0.000245
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MYEVKLDAFNGPLDLLLHLIQKFEIDIYDIPMQALTEQYMQYVHAMKQLEINIASEYLVLASELLMIKSKMLLPQSTSDMDVDDDPREDLVGRLIEYQNYKEYTAILNDMKEERDFYFTKRPTDLSHLETDESWDPNHTIDLTELIVAYQRVKNRVELNTPKSVEIRKETFTIQQATEQVTSRLKDKDHFNFFSLFTFSEPIEQVVTHFLAILEMSKAGIINIEQQRNFEDINIIRGVNYHFG

⊟Experimental data[edit | edit source]

  • experimentally validated: PeptideAtlas
  • protein localization: Cytoplasmic [1] [2]
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Dörte Becher, Kristina Hempel, Susanne Sievers, Daniela Zühlke, Jan Pané-Farré, Andreas Otto, Stephan Fuchs, Dirk Albrecht, Jörg Bernhardt, Susanne Engelmann, Uwe Völker, Jan Maarten van Dijl, Michael Hecker
    A proteomic view of an important human pathogen--towards the quantification of the entire Staphylococcus aureus proteome.
    PLoS One: 2009, 4(12);e8176
    [PubMed:19997597] [WorldCat.org] [DOI] (I e)
  2. ↑ Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
    The Staphylococcus aureus proteome.
    Int J Med Microbiol: 2014, 304(2);110-20
    [PubMed:24439828] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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