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NCBI: 26-AUG-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA2006 [new locus tag: SA_RS11550 ]
  • pan locus tag?: SAUPAN005623000
  • symbol: SA2006
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA2006 [new locus tag: SA_RS11550 ]
  • symbol: SA2006
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 2278257..2278682
  • length: 426
  • essential: no DEG other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGAAACTAAAATCATTTGTTACTGCCACTTTAGCATTGGGATTATTATCAACAGTAGGT
    GCAGCTTTACCGAGTCATGAAGCATCTGCAGATAGTAATAACGGTTATAAGGAATTGACA
    ATGGATGGAAAACACACTGTGCCTTACACGATCTCAGTAGATGGTATTACTGCATTACAT
    CGAACTTACTTTGTTTTTCCAGAAAATAAAAAGGTACTTTATCAAGAAATTGACAGTAAA
    GTAAAAAATGAATTAGCTTCACAACGTGGTGTTACAACAGAAAAAATTAATAATGCACAA
    ACAGCAACGTATACACTTACTTTGAATGATGGTAATAAAAAAGTAGTGAATCTAAAGAAA
    AATGACGACGCTAAAAATTCAATTGATCCAAGTACAATCAAACAAATACAAATTGTAGTT
    AAATAA
    60
    120
    180
    240
    300
    360
    420
    426

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA2006 [new locus tag: SA_RS11550 ]
  • symbol: SA2006
  • description: hypothetical protein
  • length: 141
  • theoretical pI: 9.78823
  • theoretical MW: 15426.5
  • GRAVY: -0.371631

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • MAP domain protein
    Regulation and Cell signaling Programmed Cell Death and Toxin-antitoxin Systems Murein hydrolase regulation and cell death  Truncated cell surface protein map-w
  • PFAM:
    no clan defined MAP; MAP domain (PF03642; HMM-score: 120)
    and 2 more
    Ubiquitin (CL0072) Stap_Strp_tox_C; Staphylococcal/Streptococcal toxin, beta-grasp domain (PF02876; HMM-score: 21.9)
    no clan defined YHR052C-B; YHR052C-B (PF23530; HMM-score: 14.1)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 9.68
    • Cellwall Score: 0.17
    • Extracellular Score: 0.16
    • Internal Helix: 1
  • DeepLocPro: Extracellular
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.0035
    • Cell wall & surface Score: 0.0209
    • Extracellular Score: 0.9755
  • LocateP: N-terminally anchored (with CS)
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: -0.17
    • Signal peptide possibility: 1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: HEASADSN
  • SignalP: Signal peptide SP(Sec/SPI) length 30 aa
    • SP(Sec/SPI): 0.992495
    • TAT(Tat/SPI): 0.005388
    • LIPO(Sec/SPII): 0.001824
    • Cleavage Site: CS pos: 30-31. ASA-DS. Pr: 0.9265
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MKLKSFVTATLALGLLSTVGAALPSHEASADSNNGYKELTMDGKHTVPYTISVDGITALHRTYFVFPENKKVLYQEIDSKVKNELASQRGVTTEKINNAQTATYTLTLNDGNKKVVNLKKNDDAKNSIDPSTIKQIQIVVK

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]