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⊟RNAIII[edit | edit source]
- synonym: S871
- general role: effector of the Agr quorum sensing system, regulation of virulence factors
- SRD: srn_3910
- target genes:
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⊟Genome View[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Regulation[edit | edit source]
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser (data for NCTC8325)
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ 1.0 1.1 R P Novick, H F Ross, S J Projan, J Kornblum, B Kreiswirth, S Moghazeh
Synthesis of staphylococcal virulence factors is controlled by a regulatory RNA molecule.
EMBO J: 1993, 12(10);3967-75
[PubMed:7691599] [WorldCat.org] (P p) - ↑ Eric Huntzinger, Sandrine Boisset, Cosmin Saveanu, Yvonne Benito, Thomas Geissmann, Abdelkader Namane, Gérard Lina, Jerome Etienne, Bernard Ehresmann, Chantal Ehresmann, Alain Jacquier, François Vandenesch, Pascale Romby
Staphylococcus aureus RNAIII and the endoribonuclease III coordinately regulate spa gene expression.
EMBO J: 2005, 24(4);824-35
[PubMed:15678100] [WorldCat.org] [DOI] (P p) - ↑ C Lebeau, F Vandenesch, T Greenland, R P Novick, J Etienne
Coagulase expression in Staphylococcus aureus is positively and negatively modulated by an agr-dependent mechanism.
J Bacteriol: 1994, 176(17);5534-6
[PubMed:8071233] [WorldCat.org] [DOI] (P p) - ↑ Clément Chevalier, Sandrine Boisset, Cédric Romilly, Benoit Masquida, Pierre Fechter, Thomas Geissmann, François Vandenesch, Pascale Romby
Staphylococcus aureus RNAIII binds to two distant regions of coa mRNA to arrest translation and promote mRNA degradation.
PLoS Pathog: 2010, 6(3);e1000809
[PubMed:20300607] [WorldCat.org] [DOI] (I e) - ↑ Ravi Kr Gupta, Thanh T Luong, Chia Y Lee
RNAIII of the Staphylococcus aureus agr system activates global regulator MgrA by stabilizing mRNA.
Proc Natl Acad Sci U S A: 2015, 112(45);14036-41
[PubMed:26504242] [WorldCat.org] [DOI] (I p) - ↑ 6.0 6.1 6.2 Sandrine Boisset, Thomas Geissmann, Eric Huntzinger, Pierre Fechter, Nadia Bendridi, Maria Possedko, Clément Chevalier, Anne Catherine Helfer, Yvonne Benito, Alain Jacquier, Christine Gaspin, François Vandenesch, Pascale Romby
Staphylococcus aureus RNAIII coordinately represses the synthesis of virulence factors and the transcription regulator Rot by an antisense mechanism.
Genes Dev: 2007, 21(11);1353-66
[PubMed:17545468] [WorldCat.org] [DOI] (P p) - ↑ E Morfeldt, D Taylor, A von Gabain, S Arvidson
Activation of alpha-toxin translation in Staphylococcus aureus by the trans-encoded antisense RNA, RNAIII.
EMBO J: 1995, 14(18);4569-77
[PubMed:7556100] [WorldCat.org] (P p) - ↑ Edward Geisinger, Rajan P Adhikari, Ruzhong Jin, Hope F Ross, Richard P Novick
Inhibition of rot translation by RNAIII, a key feature of agr function.
Mol Microbiol: 2006, 61(4);1038-48
[PubMed:16879652] [WorldCat.org] [DOI] (P p) - ↑ Svetlana Chabelskaya, Valérie Bordeau, Brice Felden
Dual RNA regulatory control of a Staphylococcus aureus virulence factor.
Nucleic Acids Res: 2014, 42(8);4847-58
[PubMed:24510101] [WorldCat.org] [DOI] (I p)
⊟Relevant publications[edit | edit source]
E Morfeldt, D Taylor, A von Gabain, S Arvidson
Activation of alpha-toxin translation in Staphylococcus aureus by the trans-encoded antisense RNA, RNAIII.
EMBO J: 1995, 14(18);4569-77
[PubMed:7556100] [WorldCat.org] (P p)